(Q36464051)

English

Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice.

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scholarly article

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19 February 2020

Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice (English)

1 reference

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19 February 2020

ascending cholangitis

0 references

0 references

multiple drug resistance

1 reference

based on heuristic

inferred from title

sclerosing cholangitis

1 reference

based on heuristic

inferred from title

5

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19 February 2020

9

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19 February 2020

author name string

Alexander G Miethke

1

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19 February 2020

Wujuan Zhang

2

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19 February 2020

Julia Simmons

3

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19 February 2020

Amy E Taylor

4

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19 February 2020

Shiva Kumar Shanmukhappa

6

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19 February 2020

Rebekah Karns

7

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19 February 2020

Shana White

8

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19 February 2020

Celine S Lages

10

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19 February 2020

Stephenson Nkinin

11

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19 February 2020

Bradley T Keller

12

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19 February 2020

Kenneth D R Setchell

13

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19 February 2020

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publication date

21 August 2015

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19 February 2020

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19 February 2020

63

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19 February 2020

2

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19 February 2020

512-523

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19 February 2020

New paradigms in the treatment of hepatic cholestasis: from UDCA to FXR, PXR and beyond

1 reference

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30 September 2017

Fibrates and cholestasis

1 reference

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30 September 2017

Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.

1 reference

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30 September 2017

Proteomic profiling in Lipocalin 2 deficient mice under normal and inflammatory conditions

1 reference

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30 September 2017

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

1 reference

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30 September 2017

Immunophenotypic alterations in resident immune cells and myocardial fibrosis in the aging rhesus macaque (Macaca mulatta) heart

1 reference

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30 September 2017

Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Pathogenesis of cholestatic liver disease and therapeutic approaches

1 reference

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30 September 2017

The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies

1 reference

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30 September 2017

New insights into autoimmune cholangitis through animal models

1 reference

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30 September 2017

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

1 reference

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30 September 2017

Genome-wide association analysis in primary sclerosing cholangitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

1 reference

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30 September 2017

TopHat: discovering splice junctions with RNA-Seq

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Liver diseases related to MDR3 (ABCB4) gene deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Cholangiocyte anion exchange and biliary bicarbonate excretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Apoptosis and hepatobiliary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Detergent Properties of Bile Salts: Correlation with Physiological Function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

Bile acid secretion, bile flow and biliary lipid secretion in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

30 September 2017

G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonists reduce the production of proinflammatory cytokines and stabilize the alternative macrophage phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

28 June 2018

Regulatory T cells control the CD8 adaptive immune response at the time of ductal obstruction in experimental biliary atresia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

28 June 2018

The role of bile salt composition in liver pathology of mdr2 (-/-) mice: differences between males and females.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

28 June 2018

Effects of bile salts on the plasma membranes of isolated rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

28 June 2018

Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

Expression of nestin in remodelling of α-naphthylisothiocyanate-induced acute bile duct injury in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

Improved analysis of bile acids in tissues and intestinal contents of rats using LC/ESI-MS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

SC-435, an ileal apical sodium co-dependent bile acid transporter (ASBT) inhibitor lowers plasma cholesterol and reduces atherosclerosis in guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4713368

21 September 2018

Monitoring hepatic cholesterol 7alpha-hydroxylase activity by assay of the stable bile acid intermediate 7alpha-hydroxy-4-cholesten-3-one in peripheral blood

1 reference

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21 September 2018

1-[4-[4[(4R,5R)-3,3-Dibutyl-7-(dimethylamino)-2,3,4,5-tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl]phenoxy]butyl]-4-aza-1-azoniabicyclo[2.2.2]octane methanesulfonate (SC-435), an ileal apical sodium-codependent bile acid transporter inhibito

1 reference

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21 September 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/26172874

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/HEP.27973

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19 February 2020

1 reference

Europe PubMed Central

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19 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26172874%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

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