(Q36474508)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22175236%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Membrane and nuclear permeabilization by polymeric pDNA vehicles: efficient method for gene delivery or mechanism of cytotoxicity? (English)

1 reference

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18 January 2020

0 references

2

1 reference

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18 January 2020

3

Theresa M Reineke

1 reference

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18 January 2020

author name string

Giovanna Grandinetti

series ordinal

1

1 reference

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18 January 2020

language of work or name

English

0 references

publication date

1 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22175236%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

published in

Molecular Pharmaceutics

1 reference

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18 January 2020

volume

9

1 reference

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18 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22175236%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

523-538

1 reference

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describes a project that uses

18 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3524998/fullTextXML

inferred from PubMed Central ID database lookup

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Biodegradable poly(2-dimethylamino ethylamino)phosphazene for in vivo gene delivery to tumor cells. Effect of polymer molecular weight

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability

30 September 2017

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Role of calcium in gene delivery

30 September 2017

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Toxic potential of materials at the nanolevel

30 September 2017

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Poly(glycoamidoamine)s for gene delivery: stability of polyplexes and efficacy with cardiomyoblast cells

30 September 2017

1 reference

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Design and development of polymers for gene delivery

30 September 2017

1 reference

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Pharmacological aspects of cytotoxic polyamine analogs and derivatives for cancer therapy

30 September 2017

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An emergency response team for membrane repair

30 September 2017

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A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

30 September 2017

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Nuclear entry of nonviral vectors

30 September 2017

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30 September 2017

Catabolism of polyamines

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Basic calcium phosphate crystals stimulate the endocytotic activity of cells--inhibition by anti-calcification agents

30 September 2017

1 reference

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A perspective of polyamine metabolism

30 September 2017

1 reference

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Improvement of exogenous DNA nuclear importation by nuclear localization signal-bearing vectors: a promising way for non-viral gene therapy?

30 September 2017

1 reference

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30 September 2017

1 reference

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DNA nanoparticles and development of DNA delivery vehicles for gene therapy

30 September 2017

1 reference

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30 September 2017

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Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes

30 September 2017

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Poly(ethylenimine)-mediated gene delivery affects endothelial cell function and viability

30 September 2017

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30 September 2017

1 reference

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Calcium enhances the transfection potency of plasmid DNA-cationic liposome complexes

30 September 2017

1 reference

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Sequence requirements for plasmid nuclear import

30 September 2017

1 reference

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Biological effects of aminoguanidine: an update

30 September 2017

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Cell-specific nuclear import of plasmid DNA.

30 September 2017

1 reference

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Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Import of plasmid DNA into the nucleus is sequence specific

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Interaction of wheat germ agglutinin with sialic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Polyethylenimine-mediated gene delivery to the lung and therapeutic applications.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Interplay of polyethyleneimine molecular weight and oligonucleotide backbone chemistry in the dynamics of antisense activity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Interaction of poly(glycoamidoamine) DNA delivery vehicles with cell-surface glycosaminoglycans leads to polyplex internalization in a manner not solely dependent on charge

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Poly(glycoamidoamine) vehicles promote pDNA uptake through multiple routes and efficient gene expression via caveolae-mediated endocytosis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Degradation of poly(glycoamidoamine) DNA delivery vehicles: polyamide hydrolysis at physiological conditions promotes DNA release

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

General structure-activity relationship for poly(glycoamidoamine)s: the effect of amine density on cytotoxicity and DNA delivery efficiency

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Lipid bilayer disruption by polycationic polymers: the roles of size and chemical functional group

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Low and high molecular weight poly(L-lysine)s/poly(L-lysine)-DNA complexes initiate mitochondrial-mediated apoptosis differently.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Oxidative metabolites are involved in polyamine-induced microglial cell death

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Low molecular weight polyethylenimine for efficient transfection of human hematopoietic and umbilical cord blood-derived CD34+ cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Extracellular calcium is required for the maintenance of plasma membrane integrity in nucleated cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Transient production of recombinant proteins by Chinese hamster ovary cells using polyethyleneimine/DNA complexes in combination with microtubule disrupting anti-mitotic agents

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Overcoming the nuclear barrier: cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524998

Mechanism of spermidine cytotoxicity at 37 degrees C and 43 degrees C in Chinese hamster ovary cells

21 September 2018

1 reference

12 December 2020

Intracellular route and transcriptional competence of polyethylenimine-DNA complexes

1 reference

12 December 2020

Deciphering the role of hydrogen bonding in enhancing pDNA-polycation interactions

1 reference

12 December 2020

Comparison of binding sites for wheat germ agglutinin on Raji lymphoblastoid cells and their isolated nuclei and plasma membranes

1 reference

12 December 2020

Gene expression profiles in mouse lung tissue after administration of two cationic polymers used for nonviral gene delivery

1 reference

12 December 2020

Identifiers

DOI

10.1021/MP200368P

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22175236%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22175236%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

22175236

1 reference