(Q36478394)

14 August 2017

1 reference

title

The Functions of PPARs in Aging and Longevity (English)

1 reference

14 August 2017

Adnan Erol

1

1 reference

14 August 2017

1 January 2007

1 reference

14 August 2017

1 reference

14 August 2017

2007

1 reference

14 August 2017

39654

1 reference

Creative Commons Attribution 3.0 Unported

14 August 2017

start time

1 January 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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30 September 2017

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30 September 2017

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30 September 2017

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Targeting components of the stress system as potential therapies for the metabolic syndrome: the peroxisome-proliferator-activated receptors.

30 September 2017

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30 September 2017

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The mitochondrial energy transduction system and the aging process

30 September 2017

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Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial

30 September 2017

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An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations

30 September 2017

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SIRT1 and endocrine signaling

30 September 2017

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Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction

30 September 2017

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30 September 2017

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The molecular inflammatory process in aging

30 September 2017

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Peroxisome proliferator-activated receptor gamma coactivator 1 in caloric restriction and other models of longevity

30 September 2017

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Oxidative stress profiling: part I. Its potential importance in the optimization of human health

30 September 2017

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Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

30 September 2017

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Extended longevity and insulin signaling in adipose tissue

30 September 2017

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Atorvastatin reverses age-related reduction in rat hepatic PPARalpha and HNF-4

30 September 2017

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Overview of caloric restriction and ageing

30 September 2017

1 reference

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Decline in skeletal muscle mitochondrial function with aging in humans

30 September 2017

1 reference

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Calorie restriction--the SIR2 connection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Peroxisome proliferator-activated receptor gamma: the more the merrier?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Aging and enhanced hepatocarcinogenicity by peroxisome proliferator-activated receptor alpha agonists

30 September 2017

1 reference

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30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Pleiotropic actions of PPAR gamma activators thiazolidinediones in cardiovascular diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

30 September 2017

1 reference

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Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

30 September 2017

1 reference

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Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Bone is a target for the antidiabetic compound rosiglitazone.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Aging: a theory based on free radical and radiation chemistry

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Peroxisome proliferator-activated receptors (PPARS): regulators of gene expression in heart and skeletal muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

From the stress theory of aging to energetic and evolutionary expectations for longevity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

PPAR-alpha effects on the heart and other vascular tissues

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

The inflammation hypothesis of aging: molecular modulation by calorie restriction.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Diabetes and other coronary heart disease risk equivalents

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Lipid metabolism in the elderly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

The biochemistry of aging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Role of redox-regulated transcription factors in inflammation, aging and age-related diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

A selective peroxisome proliferator-activated receptor-gamma (PPARgamma) modulator blocks adipocyte differentiation but stimulates glucose uptake in 3T3-L1 adipocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Peroxisome proliferator-activated receptor gamma ligands inhibit estrogen biosynthesis in human breast adipose tissue: possible implications for breast cancer therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Biology of senescent liver peroxisomes: role in hepatocellular aging and disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Aging and oxidative stress: modulation by dietary restriction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Age, anatomic site, and the replication and differentiation of adipocyte precursors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Expression and function of PPARgamma in rat and human vascular smooth muscle cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Lipid oxidation by heart mitochondria from young adult and senescent rats

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Oxidative Stress, Redox Imbalance, and the Aging Process

28 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Caloric restriction results in decreased expression of peroxisome proliferator-activated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding protein knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Age-associated changes in fat metabolism in the rat and its relation to sympathetic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Modulation of PPAR in aging, inflammation, and calorie restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Decreased longevity and enhancement of age-dependent lesions in mice lacking the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Different response of senescent female Sprague-Dawley rats to gemfibrozil and rosiglitazone administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Amelioration of age-related inflammation and oxidative stress by PPARgamma activator: suppression of NF-kappaB by 2,4-thiazolidinedione.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Constitutive expression of peroxisome proliferator-activated receptor alpha-regulated genes in dwarf mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Divergent effects of caloric restriction on gene expression in normal and long-lived mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

PPARalpha activators may be good candidates as antiaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

The Role of PPARs in the Transcriptional Control of Cellular Processes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

21 September 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Expression of the Peroxisome Proliferator-activated Receptor Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2007%2F39654

Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2254525

Peroxisome Proliferator-activated Receptor α Activation Modulates Cellular Redox Status, Represses Nuclear Factor-κB Signaling, and Reduces Inflammatory Cytokine Production in Aging

21 October 2018

1 reference

12 December 2020

Dietary restriction at old age lowers mitochondrial oxygen radical production and leak at complex I and oxidative DNA damage in rat brain

1 reference

12 December 2020

Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity

1 reference

12 December 2020

Potent inhibitory effect of troglitazone on carotid arterial wall thickness in type 2 diabetes

1 reference

12 December 2020

Regulation of Fatty Acid Utilization in Isolated Perfused Rat Hearts

1 reference

12 December 2020

Control of mitochondrial gene expression in the aging rat myocardium

1 reference

12 December 2020

Regulation of mitochondrial respiration in senescence

1 reference

12 December 2020

Aging-induced decrease in the PPAR-alpha level in hearts is improved by exercise training

1 reference

12 December 2020

Interleukin-6 (IL-6) is still the leading biomarker of the metabolic and aging related disorders

1 reference

12 December 2020

Identifiers

DOI

10.1155/2007/39654

1 reference

14 August 2017

1 reference

14 August 2017

1 reference

PMCID

2254525