(Q35080447)

6 August 2017

1 reference

title

PPAR-alpha effects on the heart and other vascular tissues (English)

1 reference

6 August 2017

author

Jean-Sébastien Annicotte

series ordinal

2

object named as

Jean-Sébastien Annicotte

0 references

Johan Auwerx

series ordinal

3

object named as

Johan Auwerx

0 references

author name string

Gordon A Francis

series ordinal

1

1 reference

6 August 2017

publication date

6 March 2003

1 reference

American Journal of Physiology Heart and Circulatory Physiology

6 August 2017

published in

1 reference

6 August 2017

volume

285

1 reference

6 August 2017

issue

1

1 reference

6 August 2017

page(s)

H1-9

1 reference

Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

PPAR signaling in the control of cardiac energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome proliferator-activated receptors in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Induction of the phospholipid transfer protein gene accounts for the high density lipoprotein enlargement in mice treated with fenofibrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wi

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome proliferator-activated receptor-alpha ligands inhibit cardiac lipoprotein lipase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

A novel mouse model of lipotoxic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Induction of IκBα Expression as a Mechanism Contributing to the Anti-inflammatory Activities of Peroxisome Proliferator-activated Receptor-α Activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Nuclear receptors and the control of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Mechanism of action of the nongenotoxic peroxisome proliferators: role of the peroxisome proliferator-activator receptor alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor alpha in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Expression of peroxisome proliferator-activated receptor alpha (PPAR alpha) in primary cultures of human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Tangier disease: a structural defect in apolipoprotein A-I (apoA-I Tangier)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Autoregulation of the human liver X receptor alpha promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor ex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Expression of the Peroxisome Proliferator-activated Receptor Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

A 16-week fenofibrate treatment increases LDL particle size in type IIA dyslipidemic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Sequence and expression of Tangier apoA-I gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

The RXR heterodimers and orphan receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Direct regulatory effect of fatty acids on macrophage lipoprotein lipase: potential role of PPARs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

PPARalpha agonists inhibit tissue factor expression in human monocytes and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Hypoxia in vivo decreases peroxisome proliferator-activated receptor alpha-regulated gene expression in rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

How many nuclear hormone receptors are there in the human genome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Myocardial substrate metabolism: implications for diabetic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome proliterator-activated receptors, orphans with ligands and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Apolipoproteins C-I and C-III as important modulators of lipoprotein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Mechanism of action of fibrates on lipid and lipoprotein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Down-regulation of hepatic lipase gene expression and activity by fenofibrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Regulation of energy substrate metabolism in the diabetic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Activation of the peroxisome proliferator-activated receptor alpha protects against myocardial ischaemic injury and improves endothelial vasodilatation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Modification of metabolism and distribution of lipids by ethyl chlorophenoxyisobutyrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Retinoids increase human apolipoprotein A-11 expression through activation of the retinoid X receptor but not the retinoic acid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Beneficial effect of gemfibrozil on the chemical composition and oxidative susceptibility of low density lipoprotein: a randomized, double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

Lipotoxic heart disease in obese rats: implications for human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

CLA-1/SR-BI Is Expressed in Atherosclerotic Lesion Macrophages and Regulated by Activators of Peroxisome Proliferator-Activated Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

NATURE OF THE HEPATOMEGALIC EFFECT PRODUCED BY ETHYL-CHLOROPHENOXY-ISOBUTYRATE IN THE RAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01118.2002

10.1152/AJPHEART.01118.2002

21 January 2018

Identifiers

DOI

1 reference

6 August 2017

1 reference