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Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition.
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Europe PubMed Central
PMC publication ID
4718409
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1 March 2020
title
Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition
(English)
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PMC publication ID
4718409
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1 March 2020
main subject
protein ubiquitination
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author
Dae-Sik Lim
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5
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4718409
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1 March 2020
author name string
Miju Kim
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1
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4718409
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1 March 2020
Minchul Kim
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2
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4718409
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1 March 2020
Seong-Jun Park
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3
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4718409
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1 March 2020
Cheolju Lee
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4
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4718409
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598551%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
publication date
23 November 2015
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4718409
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1 March 2020
published in
EMBO Reports
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4718409
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1 March 2020
volume
17
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4718409
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1 March 2020
issue
1
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PMC publication ID
4718409
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598551%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
page(s)
64-78
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4718409
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retrieved
1 March 2020
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11 June 2022
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cites work
Transcriptional co-repressor function of the hippo pathway transducers YAP and TAZ.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
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PubMed Central
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30 September 2017
AMPK modulates Hippo pathway activity to regulate energy homeostasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
The emerging roles of YAP and TAZ in cancer
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30 September 2017
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
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30 September 2017
Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
The biology of YAP/TAZ: hippo signaling and beyond
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30 September 2017
YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response
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The Hippo signaling pathway in stem cell biology and cancer
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Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer
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30 September 2017
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility
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PubMed Central
reference URL
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30 September 2017
Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions
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30 September 2017
Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation
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PubMed Central
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30 September 2017
USP9X expression correlates with tumor progression and poor prognosis in esophageal squamous cell carcinoma
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30 September 2017
Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
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30 September 2017
The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis
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30 September 2017
Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos.
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30 September 2017
cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.
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PubMed Central
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30 September 2017
LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
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PubMed Central
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30 September 2017
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma
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30 September 2017
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
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30 September 2017
Coordinating developmental signaling: novel roles for the Hippo pathway.
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30 September 2017
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
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30 September 2017
Systematic and quantitative assessment of the ubiquitin-modified proteome
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30 September 2017
Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor
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PubMed Central
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30 September 2017
Role of YAP/TAZ in mechanotransduction
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30 September 2017
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions
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PubMed Central
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30 September 2017
An atlas of altered expression of deubiquitinating enzymes in human cancer
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30 September 2017
Hippo pathway-independent restriction of TAZ and YAP by angiomotin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Angiomotin-like proteins associate with and negatively regulate YAP1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
USP9X enhances the polarity and self-renewal of embryonic stem cell-derived neural progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
A crucial role of WW45 in developing epithelial tissues in the mouse
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
retrieved
30 September 2017
Elucidation of a universal size-control mechanism in Drosophila and mammals
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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30 September 2017
Hippo pathway regulation by cell morphology and stress fibers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
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28 June 2018
Modulating F-actin organization induces organ growth by affecting the Hippo pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
retrieved
28 June 2018
Metabolic control of YAP and TAZ by the mevalonate pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
retrieved
21 September 2018
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4718409
retrieved
21 September 2018
Identifiers
DOI
10.15252/EMBR.201540809
1 reference
stated in
Europe PubMed Central
PMC publication ID
4718409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598551%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PMC publication ID
4718409
1 reference
stated in
Europe PubMed Central
PMC publication ID
4718409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598551%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed publication ID
26598551
1 reference
stated in
Europe PubMed Central
PMC publication ID
4718409
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598551%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
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