(Q36482190)

English

Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1 reference

based on heuristic

inferred from title

Alport syndrome

1 reference

based on heuristic

inferred from title

author name string

Dominic Cosgrove

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Daniel T Meehan

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Duane Delimont

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Ambra Pozzi

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Xiwu Chen

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Kathyrn D Rodgers

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Richard M Tempero

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Marisa Zallocchi

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Velidi H Rao

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

7 February 2008

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

172

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

761-773

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Role for macrophage metalloelastase in glomerular basement membrane damage associated with alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

p38 MAP kinase inhibitors: many are made, but few are chosen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: implications for capillary basement membrane pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

PDGF-BB enhances alpha1beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Collagen-binding integrin alpha1beta1 regulates intestinal inflammation in experimental colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Autocrine activation of the IGF-I signaling pathway in mesangial cells isolated from diabetic NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Alterations of vitronectin and its receptor alpha(v) integrin in the rat renal glomerular wall during diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Development of matrix metalloproteinase inhibitors in cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Alport syndrome. An inherited disorder of renal, ocular, and cochlear basement membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Regulation of matrix metalloproteinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

Glomerular epithelial and mesangial cells differentially modulate the binding specificities of VLA-1 and VLA-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

D-valine as a selective agent for normal human and rodent epithelial cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

30 September 2017

A new method for large scale isolation of kidney glomeruli from mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

28 June 2018

Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

28 June 2018

Overexpression of alpha1beta1 integrin directly affects rat mesangial cell behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

28 June 2018

Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

28 June 2018

Improved methods for culturing rat glomerular cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

28 June 2018

The alpha 1-alpha 6 subunits of integrins are characteristically expressed in distinct segments of developing and adult human nephron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

28 June 2018

Glomerular injury is exacerbated in diabetic integrin alpha1-null mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Reactive site mutations in tissue inhibitor of metalloproteinase-3 disrupt inhibition of matrix metalloproteinases but not tumor necrosis factor-alpha-converting enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Blocking of alpha 5 integrin stimulates production of TGF-beta and PAI-1 by human mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Treatment with an antibody to VLA-1 integrin reduces glomerular and tubulointerstitial scarring in a rat model of crescentic glomerulonephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Effects of anti-alpha1 integrin subunit antibody on anti-Thy-1 glomerulonephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Requirement for tyrosine kinase-ERK1/2 signaling in alpha 1 beta 1 integrin-mediated collagen matrix remodeling by rat mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Global gene expression analysis reveals a role for the alpha 1 integrin in renal pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Cross-talk between alpha(4)beta(1)/alpha(5)beta(1) and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Amplification of IL-1 beta-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-kappa B and activating protein-1 and involves activation of the mitogen-activated prot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Regulation of survival and death of mesangial cells by extracellular matrix.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258247

21 September 2018

Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha1beta1 integrin-mediated collagen matrix remodeling by rat mesangial cells is differentially regulated by transforming growth factor-beta and platelet-derived growth factor-BB

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesangial cells and their adhesive properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BAY 12-9566, a novel inhibitor of matrix metalloproteinases with antiangiogenic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An MMP-9 mutant without gelatinolytic activity as a novel TIMP-1-antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesangial cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glomerular distribution and gelatinolytic activity of matrix metalloproteinases in human glomerulonephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of Alport syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocytes may promote myofibroblast accumulation and apoptosis in Alport renal fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of rat glomerular epithelial cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta (TGF-beta) stimulates the expression of beta1 integrins and adhesion by rat mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18258846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2008.070473

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

0 references

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