(Q36484646)

14 August 2017

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title

Metabonomics techniques and applications to pharmaceutical research & development (English)

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14 August 2017

Jeremy K Nicholson

3

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Elaine Holmes

series ordinal

2

object named as

Elaine Holmes

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14 August 2017

John C Lindon

1

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14 August 2017

publication date

25 May 2006

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14 August 2017

published in

Pharmaceutical Research

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14 August 2017

volume

23

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14 August 2017

issue

6

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14 August 2017

page(s)

1075-1088

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NMR Spectroscopy of Biofluids

14 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-0025-Z

Metabolomic applications of electrochemistry/mass spectrometry

21 January 2018

1 reference

12 December 2020

Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry

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12 December 2020

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets

1 reference

12 December 2020

Tissue targeted metabonomics: metabolic profiling by microdialysis sampling and microcoil NMR.

1 reference

12 December 2020

A Pilot Study to Investigate Effects of Inulin on Caco-2 Cells through In Vitro Metabolic Fingerprinting

1 reference

12 December 2020

Metabonomics: a platform for studying drug toxicity and gene function

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12 December 2020

Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

1 reference

12 December 2020

Cryogenic Probe13C NMR Spectroscopy of Urine for Metabonomic Studies

1 reference

12 December 2020

Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis

1 reference

12 December 2020

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

1 reference

12 December 2020

Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks

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12 December 2020

Metabolomics – the link between genotypes and phenotypes

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12 December 2020

Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis

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12 December 2020

Metabolomics and machine learning: explanatory analysis of complex metabolome data using genetic programming to produce simple, robust rules

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12 December 2020

A Functional Analysis of Mouse Models of Cardiac Disease through Metabolic Profiling

1 reference

12 December 2020

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

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12 December 2020

Pattern recognition analysis of high resolution 1H NMR spectra of urine. A nonlinear mapping approach to the classification of toxicological data

1 reference

12 December 2020

Summary recommendations for standardization and reporting of metabolic analyses

1 reference

12 December 2020

Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition 1H NMR study

1 reference

12 December 2020

Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies

1 reference

12 December 2020

Metabonomic identification of two distinct phenotypes in Sprague-Dawley (Crl:CD(SD)) rats

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12 December 2020

NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats

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12 December 2020

A proposed framework for the description of plant metabolomics experiments and their results

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12 December 2020

Focused metabolomic profiling in the drug development process: advances from lipid profiling

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12 December 2020

An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy

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12 December 2020

An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver

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12 December 2020

Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism

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12 December 2020

Global metabolite analysis of yeast: evaluation of sample preparation methods

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12 December 2020

Pharmaco-metabonomic phenotyping and personalized drug treatment

1 reference

12 December 2020

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

1 reference

12 December 2020

Proton nuclear magnetic resonance-based metabonomics for rapid diagnosis of meningitis and ventriculitis

1 reference

12 December 2020

High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies.

1 reference

12 December 2020

Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

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12 December 2020

Metabolomics Standards Workshop and the development of international standards for reporting metabolomics experimental results

1 reference

12 December 2020

Functional genomics via metabolic footprinting: monitoring metabolite secretion by Escherichia coli tryptophan metabolism mutants using FT-IR and direct injection electrospray mass spectrometry

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12 December 2020

Metabolic profiling of the effects of D-galactosamine in liver spheroids using (1)H NMR and MAS-NMR spectroscopy

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12 December 2020

Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification

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12 December 2020

NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition

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12 December 2020

High-resolution magic angle spinning MRS of breast cancer tissue

1 reference

12 December 2020

Application of pattern recognition methods to the analysis and classification of toxicological data derived from proton nuclear magnetic resonance spectroscopy of urine

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12 December 2020

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

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12 December 2020

Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

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12 December 2020

Metabonomics with 1H-NMR spectroscopy and liquid chromatography-mass spectrometry applied to the investigation of metabolic changes caused by gentamicin-induced nephrotoxicity in the rat.

1 reference

12 December 2020

An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers.

1 reference

12 December 2020

Detection of epithelial ovarian cancer using 1H-NMR-based metabonomics

1 reference

12 December 2020

High-resolution magic angle spinning 1H NMR spectroscopic studies on intact rat renal cortex and medulla

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12 December 2020

Proton HR‐MAS spectroscopy and quantitative pathologic analysis of MRI/3D‐MRSI‐targeted postsurgical prostate tissues

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12 December 2020

Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development

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12 December 2020

750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma

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12 December 2020

NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach

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12 December 2020

Genomics and metabolomics as markers for the interaction of diet and health: lessons from lipids

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12 December 2020

Comparative metabonomics of differential hydrazine toxicity in the rat and mouse

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12 December 2020

The challenges of modeling mammalian biocomplexity

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12 December 2020

Comparison of in vivo 1H MRS of human brain tumours with 1H HR-MAS spectroscopy of intact biopsy samples in vitro

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12 December 2020

A rapid screening approach to metabonomics using UPLC and oa-TOF mass spectrometry: application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice

1 reference

12 December 2020

Proton nuclear magnetic resonance spectroscopy of body fluids in the field of inborn errors of metabolism.

1 reference

12 December 2020

Correlation of high-resolution magic angle spinning proton magnetic resonance spectroscopy with histopathology of intact human brain tumor specimens.

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12 December 2020

Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

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12 December 2020

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project

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12 December 2020

High-resolution diffusion and relaxation edited one- and two-dimensional 1H NMR spectroscopy of biological fluids

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12 December 2020

Biochemical classification of kidney carcinoma biopsy samples using magic-angle-spinning 1H nuclear magnetic resonance spectroscopy

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12 December 2020

10.1007/S11095-006-0025-Z

Identifiers

DOI

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14 August 2017

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