(Q36489948)

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Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

amyotrophic lateral sclerosis

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1 reference

based on heuristic

inferred from title

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26795035%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

13

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11 June 2020

author name string

Su Min Lim

1

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11 June 2020

Won Jun Choi

2

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11 June 2020

Yuanchao Xue

4

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11 June 2020

Ji Young Choi

5

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11 June 2020

Sung Hoon Kim

6

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11 June 2020

Minyeop Nahm

7

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11 June 2020

Young-Eun Kim

8

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11 June 2020

Jinhyuk Lee

9

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11 June 2020

Min-Young Noh

10

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11 June 2020

Seungbok Lee

11

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11 June 2020

Sejin Hwang

12

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11 June 2020

Xiang-Dong Fu

14

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11 June 2020

Seung Hyun Kim

15

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11 June 2020

publication date

22 January 2016

1 reference

Europe PubMed Central

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14 August 2017

Molecular Neurodegeneration

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26795035%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

11

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26795035%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26795035%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Direct reprogramming of Huntington's disease patient fibroblasts into neuron-like cells leads to abnormal neurite outgrowth, increased cell death, and aggregate formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

State of play in amyotrophic lateral sclerosis genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Compromised paraspeckle formation as a pathogenic factor in FUSopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

The genetics and neuropathology of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

CHARMM: the biomolecular simulation program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

30 September 2017

Identification of mutations in Korean patients with amyotrophic lateral sclerosis using multigene panel testing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

28 June 2018

ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

28 June 2018

De novo FUS mutations in 2 Korean patients with sporadic amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

21 September 2018

Mutations in the 3' untranslated region of FUS causing FUS overexpression are associated with amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

21 September 2018

Rodent models of amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

21 September 2018

De novo FUS gene mutations are associated with juvenile-onset sporadic amyotrophic lateral sclerosis in China.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

21 September 2018

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

21 September 2018

Screening of the SOD1, FUS, TARDBP, ANG, and OPTN mutations in Korean patients with familial and sporadic ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4722778

21 September 2018

Novel missense and truncating mutations in FUS/TLS in familial ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/26795035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

De novo FUS mutations are the most frequent genetic cause in early-onset German ALS patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26795035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13024-016-0075-6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26795035%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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Europe PubMed Central

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11 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

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11 June 2020

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