(Q36492687)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735154%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

review article

1 reference

title

Biological activity and biotechnological aspects of peptide nucleic acid (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735154%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

0 references

1 reference

5

1 reference

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28 January 2020

author name string

Karin E Lundin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735154%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Liam Good

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735154%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Roger Strömberg

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735154%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Astrid Gräslund

4

1 reference

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28 January 2020

publication date

1 January 2006

1 reference

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28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735154%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735154%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

1-51

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Down-regulation of amyloid precursor protein by peptide nucleic acid oligomer in cultured rat primary neurons and astrocytes

28 January 2020

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7 January 2021

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7 January 2021

Sequence selective double strand DNA cleavage by peptide nucleic acid (PNA) targeting using nuclease S1

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7 January 2021

Stability of peptide nucleic acids in human serum and cellular extracts

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

The translation start codon region is sensitive to antisense PNA inhibition in Escherichia coli

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7 January 2021

Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA.

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7 January 2021

Solution structure of a peptide nucleic acid-DNA duplex

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

(1S,2R/1R,2S)-ainocyclohexyl glycyl thymine PNA: synthesis, monomer crystal structures, and DNA/RNA hybridization studies

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7 January 2021

Backbone-extended pyrrolidine peptide nucleic acids (bepPNA): design, synthesis and DNA/RNA binding studies

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7 January 2021

(1S,2R/1R,2S)-cis-cyclopentyl PNAs (cpPNAs) as constrained PNA analogues: synthesis and evaluation of aeg-cpPNA chimera and stereopreferences in hybridization with DNA/RNA.

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7 January 2021

cis-Cyclopentyl PNA (cpPNA) as constrained chiral PNA analogues: stereochemical dependence of DNA/RNA hybridization

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7 January 2021

Synthesis and evaluation of (1S,2R/1R,2S)-aminocyclohexylglycyl PNAs as conformationally preorganized PNA analogues for DNA/RNA recognition

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7 January 2021

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7 January 2021

Functional dissection of RNA polymerase III termination using a peptide nucleic acid as a transcriptional roadblock

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7 January 2021

Identification of determinants for inhibitor binding within the RNA active site of human telomerase using PNA scanning

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7 January 2021

Cellular delivery of peptide nucleic acids and inhibition of human telomerase

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7 January 2021

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7 January 2021

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7 January 2021

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The alpha-helical peptide nucleic acid concept: merger of peptide secondary structure and codified nucleic acid recognition

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7 January 2021

Sequence-specific protection of duplex DNA against restriction and methylation enzymes by pseudocomplementary PNAs

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7 January 2021

Translating the Histone Code

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7 January 2021

Peptide nucleic acid antisense prolongs skin allograft survival by means of blockade of CXCR3 expression directing T cells into graft.

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7 January 2021

Transduction peptides: from technology to physiology

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7 January 2021

Intracellular Uptake and Inhibition of Gene Expression by PNAs and PNA−Peptide Conjugates†

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7 January 2021

Extending recognition by peptide nucleic acids (PNAs): binding to duplex DNA and inhibition of transcription by tail-clamp PNA-peptide conjugates

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7 January 2021

Cationic TAT peptide transduction domain enters cells by macropinocytosis.

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7 January 2021

Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain

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7 January 2021

Deletion of individual exons and induction of soluble murine interleukin-5 receptor-alpha chain expression through antisense oligonucleotide-mediated redirection of pre-mRNA splicing.

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7 January 2021

Anti-TAR polyamide nucleotide analog conjugated with a membrane-permeating peptide inhibits human immunodeficiency virus type 1 production

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7 January 2021

Oxy-peptide nucleic acid with a pyrrolidine ring that is configurationally optimized for hybridization with DNA.

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7 January 2021

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Forced intercalation probes (FIT Probes): thiazole orange as a fluorescent base in peptide nucleic acids for homogeneous single-nucleotide-polymorphism detection

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7 January 2021

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7 January 2021

PNA for one-base differentiating protection of DNA from nuclease and its use for SNPs detection

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7 January 2021

Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates

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7 January 2021

Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA.

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7 January 2021

Hybridization of DNA and PNA molecular beacons to single-stranded and double-stranded DNA targets.

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7 January 2021

Kinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA.

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7 January 2021

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HIV Rev peptides conjugated with peptide nucleic acids and their efficient binding to RRE RNA.

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Conformationally constrained PNA analogues: structural evolution toward DNA/RNA binding selectivity

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Transcription-mediated binding of peptide nucleic acid (PNA) to double-stranded DNA: sequence-specific suicide transcription

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7 January 2021

Structural Characterization of PNA-DNA Duplexes by NMR. Evidence for DNA in a B-like Conformation

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7 January 2021

Targeted delivery of plasmid DNA to myogenic cells via transferrin-conjugated peptide nucleic acid

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7 January 2021

Transcription Activation by a PNA-Peptide Chimera in a Mammalian Cell Extract

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7 January 2021

Efficient and isoform-selective inhibition of cellular gene expression by peptide nucleic acids

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7 January 2021

Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA.

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7 January 2021

Is VP22 nuclear homing an artifact?

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7 January 2021

Cooperative strand invasion of supercoiled plasmid DNA by mixed linear PNA and PNA-peptide chimeras.

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7 January 2021

Recent advances in the development of peptide nucleic acid as a gene-targeted drug

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7 January 2021

Inhibition of Tat-mediated transactivation of HIV-1 LTR transcription by polyamide nucleic acid targeted to TAR hairpin element

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7 January 2021

Peptide Nucleic Acids Targeted to the Amyloid Precursor Protein

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7 January 2021

Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration

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7 January 2021

Peptide nucleic acids specifically cause antigene effects in vivo by systemic injection

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7 January 2021

Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex

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7 January 2021

Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter.

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7 January 2021

Zn2+-dependent peptide nucleic acids probes.

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7 January 2021

Synthesis and DNA binding properties of dioxime-peptide nucleic acids

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7 January 2021

Peptide nucleic acid-metal complex conjugates: facile modulation of PNA-DNA duplex stability.

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7 January 2021

Synthesis and DNA binding properties of terminally modified peptide nucleic acids.

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7 January 2021

Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters

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7 January 2021

Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides

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7 January 2021

The population genetics and evolutionary epidemiology of RNA viruses

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7 January 2021

Emerging significance of plasmid DNA nuclear import in gene therapy

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7 January 2021

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

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https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

A cyclopentane conformational restraint for a peptide nucleic acid: design, asymmetric synthesis, and improved binding affinity to DNA and RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Inhibition of Staphylococcus aureus gene expression and growth using antisense peptide nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Sequence specific inhibition of DNA restriction enzyme cleavage by PNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Extended target sequence specificity of PNA-minor-groove binder conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Molecular basis of bacterial outer membrane permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Recognition of RNA by amide modified backbone nucleic acids: molecular dynamics simulations of DNA-RNA hybrids in aqueous solution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

PNA molecular beacons for rapid detection of PCR amplicons

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

NF-kappaB in human disease: current inhibitors and prospects for de novo structure based design of inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Vector-mediated delivery of a polyamide ("peptide") nucleic acid analogue through the blood-brain barrier in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

The peptide nucleic acids as probes for chromosomal analysis: application to human oocytes, polar bodies and preimplantation embryos.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

The chromosomal analysis of human oocytes. An overview of established procedures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Anti-gene peptide nucleic acid targeted to proviral HIV-1 DNA inhibits in vitro HIV-1 replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Short PNA molecular beacons for real-time PCR allelic discrimination of single nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Synthesis and in vitro evaluation of PNA-peptide-DETA conjugates as potential cell penetrating artificial ribonucleases.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Crystal Structure of a Partly Self-Complementary Peptide Nucleic Acid (PNA) Oligomer Showing a Duplex−Triplex Network†

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

(S,S)-trans-cyclopentane-constrained peptide nucleic acids. a general backbone modification that improves binding affinity and sequence specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Metal incorporation in modified PNA duplexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Gene delivery by a steroid-peptide nucleic acid conjugate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

A peptide nucleic acid-neamine conjugate that targets and cleaves HIV-1 TAR RNA inhibits viral replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Sequence-specific inhibition of duck hepatitis B virus reverse transcription by peptide nucleic acids (PNA).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Site-directed recombination via bifunctional PNA-DNA conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Synthesis of trifunctional PNA-benzophenone derivatives for mitochondrial targeting, selective DNA binding, and photo-cross-linking

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Synthesis and properties of RNA analogues having amides as interuridine linkages at selected positions.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Predicting the efficacy of short oligonucleotides in antisense and RNAi experiments with boosted genetic programming.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Approaches for the sequence-specific knockdown of mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Identification of a key target sequence to block human immunodeficiency virus type 1 replication within the gag-pol transframe domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Solid-Phase Synthesis of Doubly Labeled Peptide Nucleic Acids as Probes for the Real-Time Detection of Hybridization This work was supported by the Fonds der Chemischen Industrie

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

The discovery of split genes and RNA splicing.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Synthesis and hybridization of novel chiral pyrrolidine based PNA analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

PNA FISH: an intelligent stain for rapid diagnosis of infectious diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Adding functional entities to plasmids.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Protease-induced release of functional peptides from bioplexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Free-probe fluorescence of light-up probes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Light-up probes: thiazole orange-conjugated peptide nucleic acid for detection of target nucleic acid in homogeneous solution.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Peptide nucleic acid antisense oligomer as a therapeutic strategy against bacterial infection: proof of principle using mouse intraperitoneal infection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Ionic Effects on the Stability and Conformation of Peptide Nucleic Acid Complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Anti-HIV-1 activity of anti-TAR polyamide nucleic acid conjugated with various membrane transducing peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Molecular beacons: probes that fluoresce upon hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Specific gene blockade shows that peptide nucleic acids readily enter neuronal cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Efficient Hydrolysis of RNA by a PNA - Diethylenetriamine Adduct

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Peptide nucleic acid (PNA) amphiphiles: synthesis, self-assembly, and duplex stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

PNA as a rare genome-cutter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

A novel pyrrolidinyl PNA showing high sequence specificity and preferential binding to DNA over RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Defining the peptide nucleic acids (PNA) length requirement for PNA binding-induced transcription and gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Genetic screening using the colour change of a PNA-DNA hybrid-binding cyanine dye.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Phospholipid membrane permeability of peptide nucleic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

PNA-based light-up probes for real-time detection of sequence-specific PCR products

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5' flanking region

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Site-selective and hydrolytic two-strand scission of double-stranded DNA using Ce(IV)/EDTA and pseudo-complementary PNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Sequence selective hydrolysis of linear DNA using conjugates of Zr(IV) complexes and peptide nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

PNA-dependent gene chemistry: stable coupling of peptides and oligonucleotides to plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Liver cell specific targeting of peptide nucleic acid oligomers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2806%2956001-8

7 January 2021

10.1016/S0065-2660(06)56001-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735154%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference