(Q44212614)

30 November 2017

title

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues (English)

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30 November 2017

Peter Sazani

1

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30 November 2017

Federica Gemignani

2

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30 November 2017

Shin-Hong Kang

3

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30 November 2017

Martin A Maier

4

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30 November 2017

Muthiah Manoharan

5

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30 November 2017

Magnus Persmark

6

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30 November 2017

Donna Bortner

7

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30 November 2017

Ryszard Kole

8

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30 November 2017

publication date

11 November 2002

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30 November 2017

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30 November 2017

volume

20

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30 November 2017

issue

12

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30 November 2017

page(s)

1228-1233

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https://scigraph.springernature.com/pub.10.1038/nbt759

30 November 2017

exact match

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cites work

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Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides.

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Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17.

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Deletion of individual exons and induction of soluble murine interleukin-5 receptor-alpha chain expression through antisense oligonucleotide-mediated redirection of pre-mRNA splicing.

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7 January 2021

Restoration of human beta-globin gene expression in murine and human IVS2-654 thalassemic erythroid cells by free uptake of antisense oligonucleotides.

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7 January 2021

Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients

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7 January 2021

Antisense therapy in oncology: new hope for an old idea?

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7 January 2021

Antisense pharmacodynamics: critical issues in the transport and delivery of antisense oligonucleotides

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7 January 2021

Preclinical and clinical pharmacology of antisense oligonucleotides

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7 January 2021

Antisense oligonucleotides: promise and reality.

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7 January 2021

Modification of alternative splicing by antisense oligonucleotides as a potential chemotherapy for cancer and other diseases

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7 January 2021

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs

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7 January 2021

'Green mice' as a source of ubiquitous green cells.

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7 January 2021

Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration

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7 January 2021

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

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7 January 2021

Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats

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7 January 2021

Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis

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7 January 2021

Intercellular adhesion molecule-1 suppression in skin by topical delivery of anti-sense oligonucleotides

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7 January 2021

Transdermal delivery of antisense compounds

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7 January 2021

Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioate, phosphorodithioate, and methylphosphonate oligonucleotides in nude mice

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7 January 2021

Pharmacokinetics of antisense oligonucleotides

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7 January 2021

In vivo evaluation of a morpholino antisense oligomer directed against tumor necrosis factor-alpha

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7 January 2021

Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides

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7 January 2021

Identifiers

DOI

10.1038/NBT759

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30 November 2017

1 reference