(Q34341868)

1 August 2017

1 reference

title

Antisense therapy in oncology: new hope for an old idea? (English)

1 reference

1 August 2017

G Hartmann

3

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author name string

I Tamm

series ordinal

1

1 reference

PubMed ID

11513935

1 August 2017

B Dörken

series ordinal

2

1 reference

PubMed ID

11513935

1 August 2017

language of work or name

English

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publication date

1 August 2001

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1 August 2017

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1 August 2017

358

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1 August 2017

489-497

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1 August 2017

9280

1 reference

Antisense therapeutics in chronic myeloid leukaemia: the promise, the progress and the problems

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Elucidating cell signaling mechanisms using antisense technology

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Molecular mechanisms of action of antisense drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Novel mechanisms for antisense-mediated regulation of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A).

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Phase I evaluation of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C-alpha, in patients with advanced cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Translational control of IS10 transposition

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Oligonucleotide therapeutics: a step forward

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

In Vivo Modulation of N-myc Expression by Continuous Perfusion with an Antisense Oligonucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Bcl-xl antisense treatment induces apoptosis in breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Antisense oligonucleotides demonstrate a dominant role of c-Ki-RAS proteins in regulating the proliferation of diploid human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Evaluation of biological role of c-Jun N-terminal kinase using an antisense approach

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Novel anticancer drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Fomivirsen - a phosphorothioate oligonucleotide for the treatment of CMV retinitis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

bcl-2 protein expression in cutaneous malignant melanoma and benign melanocytic nevi.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Chemosensitisation of malignant melanoma by BCL2 antisense therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Regulators and Effectors of ras Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Phase I and pharmacologic study of the tyrosine kinase inhibitor SU101 in patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Oligonucleotide therapeutics for hematologic disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Antitumor activity and pharmacokinetics of a mixed-backbone antisense oligonucleotide targeted to the RIalpha subunit of protein kinase A after oral administration

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Mechanism and function of a newly identified CpG DNA motif in human primary B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Oligodeoxynucleotides enhance lipopolysaccharide-stimulated synthesis of tumor necrosis factor: dependence on phosphorothioate modification and reversal by heparin.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

A Toll-like receptor recognizes bacterial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Causing a commotion in the blood: immunotherapy progresses from bacteria to bacterial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Bias in nucleotide composition of antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

X-linked IAP is a direct inhibitor of cell-death proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

A single BIR domain of XIAP sufficient for inhibiting caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Tumor Content of the Antiapoptosis Molecule Survivin and Recurrence of Bladder Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Livin, a novel inhibitor of apoptosis protein family member

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Control of apoptosis and mitotic spindle checkpoint by survivin

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Survivin initiates cell cycle entry by the competitive interaction with Cdk4/p16(INK4a) and Cdk2/cyclin E complex activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Survivin' cell-separation anxiety

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Escaping cell death: survival proteins in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding gene

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Overexpression of resistance-related proteins (metallothioneins, glutathione-S-transferase pi, heat shock protein 27, and lung resistance-related protein) in osteosarcoma. Relationship with poor prognosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Telomerase as a potential molecular target to study G-quartet phosphorothioates

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

Morpholino antisense oligomers: the case for an RNase H-independent structural type

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2801%2905629-X

7 January 2021

10.1016/S0140-6736(01)05629-X

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11513935