(Q36498272)

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Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors (English)

1 reference

Europe PubMed Central

14 August 2017

Stefan G. Sarafianos

3

1 reference

Europe PubMed Central

14 August 2017

object named as

Eiichi N Kodama

2

0 references

object named as

Masao Matsuoka

6

0 references

Yasuko Sakagami

5

object named as

Yasuko Sakagami

1 reference

Europe PubMed Central

14 August 2017

1

object named as

Atsuko Hachiya

1 reference

Europe PubMed Central

14 August 2017

Hiroyuki Gatanaga

8

object named as

Hiroyuki Gatanaga

1 reference

Europe PubMed Central

14 August 2017

Masafumi Takiguchi

7

object named as

Masafumi Takiguchi

1 reference

Europe PubMed Central

14 August 2017

author name string

Matthew M Schuckmann

4

1 reference

Europe PubMed Central

14 August 2017

Shinichi Oka

9

1 reference

Europe PubMed Central

14 August 2017

language of work or name

0 references

publication date

23 January 2008

1 reference

Europe PubMed Central

14 August 2017

Journal of Virology

1 reference

Europe PubMed Central

14 August 2017

82

1 reference

Europe PubMed Central

14 August 2017

7

1 reference

Europe PubMed Central

14 August 2017

3261-3270

1 reference

Europe PubMed Central

14 August 2017

N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance

1 reference

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30 September 2017

Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3'-azido-3'-dideoxythymidine.

1 reference

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30 September 2017

Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3'-azido-3'-deoxythymidine resistance

1 reference

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30 September 2017

HIV-1 protease and reverse transcriptase mutations for drug resistance surveillance

1 reference

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30 September 2017

Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance

1 reference

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30 September 2017

Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors

1 reference

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Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097.

1 reference

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30 September 2017

In vitro selection and analysis of human immunodeficiency virus type 1 resistant to derivatives of beta-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine

1 reference

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HIV-1 Protease and reverse-transcriptase mutations: correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance

1 reference

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30 September 2017

Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision

1 reference

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Mutations conferring resistance to human immunodeficiency virus type 1 fusion inhibitors are restricted by gp41 and Rev-responsive element functions

1 reference

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30 September 2017

Gln145Met/Leu changes in human immunodeficiency virus type 1 reverse transcriptase confer resistance to nucleoside and nonnucleoside analogs and impair virus replication.

1 reference

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30 September 2017

Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency

1 reference

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30 September 2017

Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors.

1 reference

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30 September 2017

Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.

1 reference

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30 September 2017

A mutation in the 3' region of the human immunodeficiency virus type 1 reverse transcriptase (Y318F) associated with nonnucleoside reverse transcriptase inhibitor resistance

1 reference

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4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro

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30 September 2017

Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA

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Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4(+) cell clone 1-10 (MAGIC-5)

1 reference

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30 September 2017

Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites

1 reference

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30 September 2017

Mutational analysis of Tyr-318 within the non-nucleoside reverse transcriptase inhibitor binding pocket of human immunodeficiency virus type I reverse transcriptase

1 reference

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30 September 2017

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

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30 September 2017

A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors

1 reference

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A novel polymorphism at codon 333 of human immunodeficiency virus type 1 reverse transcriptase can facilitate dual resistance to zidovudine and L-2',3'-dideoxy-3'-thiacytidine

1 reference

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Novel mutation (K70E) in human immunodeficiency virus type 1 reverse transcriptase confers decreased susceptibility to 9-[2-(phosphonomethoxy)ethyl]adenine in vitro

1 reference

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Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1.

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Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy

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Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

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Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.

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Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel.

1 reference

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Novel patterns of nevirapine resistance-associated mutations of human immunodeficiency virus type 1 in treatment-naïve patients

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Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir

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Nevirapine-selected mutations Y181I/C of HIV-1 reverse transcriptase confer cross-resistance to stavudine

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Detection of a new HIV-1 reverse transcriptase mutation (Q145M) conferring resistance to nucleoside and non-nucleoside inhibitors in a patient failing highly active antiretroviral therapy.

1 reference

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A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to non-nucleoside reverse transcriptase inhibitors

1 reference

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Cross-resistance among nonnucleoside reverse transcriptase inhibitors limits recycling efavirenz after nevirapine failure

1 reference

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Drug-resistant reverse transcriptase genotyping and phenotyping of B and non-B subtypes (F and A) of human immunodeficiency virus type I found in Brazilian patients failing HAART.

1 reference

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Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs

1 reference

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Active HIV-1 redistribution and replication in the brain with HIV encephalitis.

1 reference

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1 reference

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21 September 2018

Identifiers

10.1128/JVI.01154-07

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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