(Q36508050)

English

Prevention of oxidative stress-mediated neuropathology and improved clinical outcome by adjunctive use of a combination of antioxidants and omega-3 fatty acids in schizophrenia

scientific article published on April 2006

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 August 2017

1 reference

Europe PubMed Central

Prevention of oxidative stress-mediated neuropathology and improved clinical outcome by adjunctive use of a combination of antioxidants and omega-3 fatty acids in schizophrenia (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

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author name string

Sahebarao P Mahadik

1

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Anilkumar Pillai

2

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Sadhana Joshi

3

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Adriana Foster

4

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

publication date

1 April 2006

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

International Review of Psychiatry

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

119-131

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Vitamin E treatment for tardive dyskinesia. Veterans Affairs Cooperative Study #394 Study Group.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Oxidative influence on development and differentiation: an overview of a free radical theory of development

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Absence of neurodegeneration and neural injury in the cerebral cortex in a sample of elderly patients with schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Supplementation with a combination of omega-3 fatty acids and antioxidants (vitamins E and C) improves the outcome of schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Essential polyunsaturated fatty acid and lipid peroxide levels in never-medicated and medicated schizophrenia patients

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Increased number of nitric oxide synthase immunoreactive Purkinje cells and dentate nucleus neurons in schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Chronic treatment with prolixin causes oxidative stress in rat brain.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Obstetric complications and schizophrenia: historical and meta-analytic review

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Apoptosis and schizophrenia: is the tumour suppressor gene, p53, a candidate susceptibility gene?

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Fat consumption and schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Oxidative damage to DNA: do we have a reliable biomarker?

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Outcome in schizophrenia and related disorders compared between developing and developed countries. A recursive partitioning re-analysis of the WHO DOSMD data.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Role of oxidative stress in neurodegeneration: recent developments in assay methods for oxidative stress and nutraceutical antioxidants

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

A novel neuronal messenger molecule in brain: the free radical, nitric oxide

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Volumes of Ventricular System Subdivisions Measured From Magnetic Resonance Images in First-Episode Schizophrenic Patients

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Schizophrenia as a chronic active brain process: a study of progressive brain structural change subsequent to the onset of schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Left ventricular enlargement associated with diagnostic outcome of schizophreniform disorder.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Red blood cell membrane essential fatty acid metabolism in early psychotic patients following antipsychotic drug treatment

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Mental illness in adults with fetal alcohol syndrome or fetal alcohol effects.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Nitric oxide and the cerebral circulation

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Essential fatty acids, lipid membrane abnormalities, and the diagnosis and treatment of schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Infants at risk for schizophrenia: sequelae of a genetic neurointegrative defect. A review and replication analysis of pandysmaturation in the Jerusalem Infant Development Study

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Ascorbate is an outstanding antioxidant in human blood plasma

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Increased platelet phospholipase A2 activity in schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

A red cell membrane abnormality in a subgroup of schizophrenic patients: evidence for two diseases

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Neurological soft signs in neuroleptic-naive and neuroleptic-treated schizophrenic patients and in normal comparison subjects.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

A follow-up magnetic resonance imaging study of schizophrenia. Relationship of neuroanatomical changes to clinical and neurobehavioral measures.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

The antioxidants of human extracellular fluids

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Neuropathology of schizophrenia: cortex, thalamus, basal ganglia, and neurotransmitter-specific projection systems

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Evidence that the activities of erythrocyte free radical scavenging enzymes and the products of lipid peroxidation are increased in different forms of schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Is the main problem in free radical damage caused by radiation, oxygen and other toxins the loss of membrane essential fatty acids rather than the accumulation of toxic materials?

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Schizophrenia as a membrane lipid disorder which is expressed throughout the body

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Fatty acid levels in the brains of schizophrenics and normal controls.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Role of gangliosides in behavioral and biochemical actions of alcohol: cell membrane structure and function

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Dietary n-3 fatty acid deficiency decreases nerve growth factor content in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Apoptotic mechanisms in the pathophysiology of schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Nitric oxide synthase (NOS) in schizophrenia: increases in cerebellar vermis.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

No differences in phospholipase-A2 activity between acute psychiatric patients and controls.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Progressive loss of cerebellar volume in childhood-onset schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Erythrocyte membrane phospholipids in psychotic patients

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Reduced erythrocyte membrane essential fatty acids and increased lipid peroxides in schizophrenia at the never-medicated first-episode of psychosis and after years of treatment with antipsychotics

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Oxidative stress during treatment with first- and second-generation antipsychotics

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

The anthropometric assessment of dysmorphic features in schizophrenia as an index of its developmental origins.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Brain abnormality in schizophrenia. A systematic and quantitative review of volumetric magnetic resonance imaging studies

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Magnetic resonance imaging of brain in people at high risk of developing schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Increased indices of free radical activity in the cerebrospinal fluid of patients with tardive dyskinesia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Increased manganese-superoxide dismutase activity in postmortem brain from neuroleptic-treated psychotic patients.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Oxidative stress and role of antioxidant and omega-3 essential fatty acid supplementation in schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Free radical pathology and antioxidant defense in schizophrenia: a review

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Oxidative injury and potential use of antioxidants in schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Programmed cell death: implications for neuropsychiatric disorders

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Progressive brain volume changes and the clinical course of schizophrenia in men: a longitudinal magnetic resonance imaging study

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Impaired antioxidant defense at the onset of psychosis.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Elevated PLA2 activity in schizophrenics and other psychiatric patients

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

A radical hypothesis for neurodegeneration

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Evidence of enhanced lipid peroxidation in the cerebrospinal fluid of patients taking phenothiazines

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Nerve growth factor in never-medicated first-episode psychotic and medicated chronic schizophrenic patients: possible implications for treatment outcome

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

A dose-ranging exploratory study of the effects of ethyl-eicosapentaenoate in patients with persistent schizophrenic symptoms

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Essential fatty acid deficiency in erythrocyte membranes from chronic schizophrenic patients, and the clinical effects of dietary supplementation

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Omega-3 fatty acids in the treatment of psychiatric disorders

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Predictors of antipsychotic treatment response in patients with first-episode schizophrenia, schizoaffective and schizophreniform disorders

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Deterioration of spatial and nonspatial reference and working memory in aged rats: protective effect of life-long calorie restriction.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

DNA damage and repair efficiency in lymphocytes from schizophrenic patients

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Reduced plasma antioxidants in first-episode patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Free radical pathology in schizophrenia: a review

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Current status of antioxidant therapy

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Increased phospholipid breakdown in schizophrenia. Evidence for the involvement of a calcium-independent phospholipase A2.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Effects of chlorpromazine on the activities of antioxidant enzymes and lipid peroxidation in the various regions of aging rat brain

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Regulation of gamma-aminobutyric acid/barbiturate receptor-gated chloride ion flux in brain vesicles by phospholipase A2: possible role of oxygen radicals

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Nutritional assessment of patients with schizophrenia: a preliminary study

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Vitamin C status in chronic schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid, and fetal brain.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Conformational changes in oxidized phospholipids and their preferential hydrolysis by phospholipase A2: a monolayer study

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Implications of normal brain development for the pathogenesis of schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Increased nitric oxide radicals in postmortem brain from patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Effects of haloperidol on antioxidant defense system enzymes in schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Abnormal age-related changes of plasma antioxidant proteins in schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Reduced level of plasma antioxidant uric acid in schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Oxidative damage and schizophrenia: an overview of the evidence and its therapeutic implications

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Red blood cell membrane dynamics in schizophrenia. II. Fatty acid composition

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Elevated blood superoxide dismutase in neuroleptic-free schizophrenia: association with positive symptoms.

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Qualitative assessment of brain morphology in acute and chronic schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Early and late environmental risk factors for schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Low concentration of nitrite and nitrate in the cerebrospinal fluid from schizophrenic patients: a pilot study

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Vitamin E treatment of tardive dyskinesia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

The unhealthy lifestyle of people with schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Alcohol dependence and hospitalization in schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Red blood cell nitric oxide levels in patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Characterization of the potential antioxidant and pro-oxidant actions of some neuroleptic drugs

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Differential effects of olanzapine on the gene expression of superoxide dismutase and the low affinity nerve growth factor receptor

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Elevated plasma lipid peroxides at the onset of nonaffective psychosis

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

The Nithsdale Schizophrenia Surveys. XIV: Plasma lipid peroxide and serum vitamin E levels in patients with and without tardive dyskinesia, and in normal subjects

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Schizophrenic symptoms and dietary intake of n-3 fatty acids

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Cu, Zn- and Mn-superoxide dismutase levels in brains of patients with schizophrenic psychosis

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Tardive dyskinesia, lipid peroxidation, and sustained amelioration with vitamin E treatment

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Peroxidation induced changes in synaptosomal transport of dopamine and gamma-aminobutyric acid

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Enzymes of the antioxidant defense system in chronic schizophrenic patients

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Vitamin E in the treatment of tardive dyskinesia: a double-blind placebo-controlled study

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Serum nitric oxide metabolite levels and the effect of antipsychotic therapy in schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Early intervention for schizophrenia: can the course of the illness be altered?

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Membrane phospholipid abnormalities in postmortem brains from schizophrenic patients

1 reference

https://api.crossref.org/works/10.1080%2F09540260600581993

21 January 2018

Identifiers

10.1080/09540260600581993

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

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