(Q36511134)

English

Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene.

scientific article published on 9 October 2012

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scholarly article

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Europe PubMed Central

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10 March 2020

Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene (English)

1 reference

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10 March 2020

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Eva M Garrido-Martin

1

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10 March 2020

Francisco-Javier Blanco

2

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10 March 2020

5

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10 March 2020

Carmelo Bernabeu

10

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10 March 2020

author name string

Mercé Roquè

3

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10 March 2020

Laura Novensà

4

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10 March 2020

Ursula E Lang

6

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10 March 2020

Toru Suzuki

7

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10 March 2020

Scott L Friedman

8

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10 March 2020

Luisa M Botella

9

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10 March 2020

publication date

9 October 2012

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10 March 2020

Circulation Research

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10 March 2020

112

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10 March 2020

1

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10 March 2020

113-127

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10 March 2020

BMP9 and BMP10 are critical for postnatal retinal vascular remodeling.

1 reference

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30 September 2017

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1 reference

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30 September 2017

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions.

1 reference

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30 September 2017

Hereditary haemorrhagic telangiectasia: pathophysiology, diagnosis and treatment

1 reference

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30 September 2017

Influence of specific blocking of the delta-like ligand 4/notch signal transduction pathway on the biological behavior of human umbilical vein endothelial cells

1 reference

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30 September 2017

The physiological role of endoglin in the cardiovascular system.

1 reference

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30 September 2017

Signaling by members of the TGF-beta family in vascular morphogenesis and disease

1 reference

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30 September 2017

Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1

1 reference

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30 September 2017

BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo

1 reference

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30 September 2017

Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.

1 reference

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30 September 2017

TGF-beta signaling in alcohol induced hepatic injury

1 reference

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30 September 2017

Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Regulation of vascular integrity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

TGF-beta signaling in vascular biology and dysfunction

1 reference

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30 September 2017

TGF-beta regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3-Sp1-KLF6 interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Bone morphogenetic protein-9 is a circulating vascular quiescence factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Role of Krüppel-like transcription factors in endothelial biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Understanding the role of transforming growth factor-beta1 in intimal thickening after vascular injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

The role of Smad3-dependent TGF-beta signal in vascular response to injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Transcriptional activation of endoglin and transforming growth factor-beta signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Microvascular endothelial injury and dysfunction during ischemic acute renal failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

The endothelium in sepsis: source of and a target for inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Krüppel-like factors: three fingers in many pies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer

1 reference

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30 September 2017

Arteriovenous malformations in mice lacking activin receptor-like kinase-1

1 reference

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30 September 2017

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

1 reference

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30 September 2017

Transcriptional activation of urokinase by the Krüppel-like factor Zf9/COPEB activates latent TGF-beta1 in vascular endothelial cells.

1 reference

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30 September 2017

Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis

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30 September 2017

Early genes induced in hepatic stellate cells during wound healing

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30 September 2017

Type I receptor serine-threonine kinase preferentially expressed in pulmonary blood vessels

1 reference

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30 September 2017

The intima: development and monoclonal responses to injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation

1 reference

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30 September 2017

Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

30 September 2017

Transforming growth factor beta in tissue fibrosis

1 reference

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30 September 2017

Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

1 reference

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30 September 2017

Functional analysis of the BMP9 response of ALK1 mutants from HHT2 patients: a diagnostic tool for novel ACVRL1 mutations

1 reference

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28 June 2018

Expression of ALK-1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

28 June 2018

Endothelial injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

28 June 2018

Radiation-induced activation of TGF-beta signaling pathways in relation to vascular damage in mouse kidneys.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537907

21 September 2018

Remodeling retinal neovascularization by ALK1 gene transfection in vitro

1 reference

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21 September 2018

Genotype-phenotype relationship in hereditary haemorrhagic telangiectasia.

1 reference

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21 September 2018

Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling

1 reference

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21 September 2018

Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells

1 reference

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21 September 2018

Transcriptional activation of transforming growth factor beta1 and its receptors by the Kruppel-like factor Zf9/core promoter-binding protein and Sp1. Potential mechanisms for autocrine fibrogenesis in response to injury.

1 reference

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21 September 2018

Increased p53 gene dosage reduces neointimal thickening induced by mechanical injury but has no effect on native atherosclerosis

1 reference

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4 December 2018

Migration of arterial wall cells. Expression of plasminogen activators and inhibitors in injured rat arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factors beta1, beta2, and beta3 and their receptors are differentially regulated during normal and impaired wound healing

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation by protein kinase C of transforming growth factor-beta 1 action on the proliferation of vascular smooth muscle cells from spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of transforming growth factor-beta1 (TGF-beta1) and urokinase-type plasminogen activator (u-PA) genes during arterial repair in the pig

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta 1 expression and myofibroblast formation during arterial repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous Endothelial Cell Activation Increases Angiogenesis: Evidence for the Direct Role of Endothelium Linking Angiogenesis and Inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse model of femoral artery denudation injury associated with the rapid accumulation of adhesion molecules on the luminal surface and recruitment of neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial cell dysfunction and nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048070

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCRESAHA.112.275586

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23048070%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23048070%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23048070%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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