(Q36511520)

English

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

scientific article published on 7 November 2012

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma (English)

1 reference

Europe PubMed Central

14 August 2017

toll-like receptor

0 references

Carol Feghali-Bostwick

13

object named as

Carol Feghali-Bostwick

1 reference

Europe PubMed Central

14 August 2017

Robert Lafyatis

object named as

Robert Lafyatis

11

0 references

Richard M. Pope

object named as

Richard M Pope

8

0 references

Gökhan M Mutlu

10

object named as

Gökhan M Mutlu

1 reference

Europe PubMed Central

14 August 2017

author name string

Swati Bhattacharyya

1

1 reference

Europe PubMed Central

14 August 2017

Kathleen Kelley

2

1 reference

Europe PubMed Central

14 August 2017

Denisa S Melichian

3

1 reference

Europe PubMed Central

14 August 2017

Zenshiro Tamaki

4

1 reference

Europe PubMed Central

14 August 2017

Feng Fang

5

1 reference

Europe PubMed Central

14 August 2017

Yunyun Su

6

1 reference

Europe PubMed Central

14 August 2017

Gilbert Feng

7

1 reference

Europe PubMed Central

14 August 2017

G R Scott Budinger

9

1 reference

Europe PubMed Central

14 August 2017

Timothy Radstake

12

1 reference

Europe PubMed Central

14 August 2017

John Varga

14

1 reference

Europe PubMed Central

14 August 2017

language of work or name

0 references

publication date

7 November 2012

1 reference

Europe PubMed Central

14 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

14 August 2017

182

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Europe PubMed Central

14 August 2017

192-205

1 reference

Europe PubMed Central

14 August 2017

1

1 reference

Europe PubMed Central

14 August 2017

Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Egr-1 induces a profibrotic injury/repair gene program associated with systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Localized expression of tenascin in systemic sclerosis-associated pulmonary fibrosis and its regulation by insulin-like growth factor binding protein 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Two signal models in innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Smad3-mediated upregulation of miR-21 promotes renal fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-β that is up-regulated in systemic sclerosis and mediates profibrotic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

MicroRNAs in idiopathic pulmonary fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Tenascin-C deficiency attenuates TGF-ß-mediated fibrosis following murine lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

DAMPening inflammation by modulating TLR signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Toll-like receptor 4: a novel signaling pathway during renal fibrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

The transcriptional cofactor nab2 is induced by tgf-Beta and suppresses fibroblast activation: physiological roles and impaired expression in scleroderma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

The role of toll-like receptors in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Human BAMBI cooperates with Smad7 to inhibit transforming growth factor-beta signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Toll-like receptors in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Essential roles for early growth response transcription factor Egr-1 in tissue fibrosis and wound healing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Transforming growth factor beta as a therapeutic target in systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

A three-dimensional view of the molecular machinery of RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

lumi: a pipeline for processing Illumina microarray

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Model-based variance-stabilizing transformation for Illumina microarray data.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

TLR4 enhances TGF-beta signaling and hepatic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

TLR4 activation mediates kidney ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

nuID: a universal naming scheme of oligonucleotides for illumina, affymetrix, and other microarrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Infectious disease, the innate immune response, and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Toll-like receptor 4 deficiency causes pulmonary emphysema.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Phylogenetic perspectives in innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

30 September 2017

TLR4 activity is required in the resolution of pulmonary inflammation and fibrosis after acute and chronic lung injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

28 June 2018

Microarray Analysis of Gene Expression Profiles in Response to Treatment with Melatonin in Lipopolysaccharide Activated RAW 264.7 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

28 June 2018

Lipopolysaccharide inhibits transforming growth factor-beta1-stimulated Smad6 expression by inducing phosphorylation of the linker region of Smad3 through a TLR4-IRAK1-ERK1/2 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

28 June 2018

Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

28 June 2018

Expression of toll-like receptors 2, 4 and 9 is increased in gingival tissue from patients with type 2 diabetes and chronic periodontitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

21 September 2018

Differential expression of toll-like receptors in patients with irritable bowel syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

21 September 2018

MicroRNA-29, a key regulator of collagen expression in systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

21 September 2018

An essential role for fibronectin extra type III domain A in pulmonary fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538029

21 September 2018

Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor ?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23141927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extra domain A of fibronectin stimulates murine mast cells via toll-like receptor 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23141927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.AJPATH.2012.09.007

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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