(Q36512526)

14 August 2017

1 reference

title

Strong-arming immune regulation: suppressing regulatory T-cell function to treat cancers (English)

1 reference

14 August 2017

Keith L Knutson

1

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PubMed ID

16787118

14 August 2017

language of work or name

English

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publication date

1 June 2006

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14 August 2017

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14 August 2017

2

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14 August 2017

3

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14 August 2017

379-389

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Central tolerance: learning self-control in the thymus

14 August 2017

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Regulating the immune system: the induction of regulatory T cells in the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Peripheral tolerance of CD8 T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Regulation of immunity by self-reactive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Antigen-specific regulatory T cells--their induction and role in infection

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

CD4+CD25+-regulatory T cells from mouse to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

CD4+ regulatory T cells: mechanisms of induction and effector function.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Thymic regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Regulatory T cells: development, function and role in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

FOXP3 acts as a rheostat of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

IPEX and FOXP3: clinical and research perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

TCRalphabeta repertoire diversity of human naturally occurring CD4+CD25+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

CCR8 is expressed by antigen-elicited, IL-10-producing CD4+CD25+ T cells, which regulate Th2-mediated granuloma formation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Regulatory T cells: peace keepers in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Induction of FOXP3-expressing regulatory CD4pos T cells by human mature autologous dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Regulatory T cells and autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Modulation of tryptophan catabolism by regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Indoleamine 2,3 dioxygenase and regulation of T cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Type 1 T regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

TGF-beta: the perpetrator of immune suppression by regulatory T cells and suicidal T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Interleukin-10 and the interleukin-10 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Neuropilin-1: a surface marker of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Role of LAG-3 in regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Antigen-specific regulatory T cells--ex vivo expansion and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Cancer immunoediting: from immunosurveillance to tumor escape

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Antibody immunity to the p53 oncogenic protein is a prognostic indicator in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Pre-existing T-cell immunity against mucin-1 in breast cancer patients and healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

CD4+CD25+ regulatory T lymphocytes in malignant pleural effusion

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Basiliximab reduces acute liver allograft rejection in pediatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Improved treatment response with basiliximab immunoprophylaxis after liver transplantation: results from a double-blind randomized placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients. CHIB 201 International Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

CTLA-4: new insights into its biological function and use in tumor immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Interleukin-10 and related cytokines and receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Biodegradable nanoparticles for direct or two-step tumor immunotargeting

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Current methods for attaching targeting ligands to liposomes and nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.3.379

21 January 2018

Identifiers

DOI

10.2217/14796694.2.3.379

1 reference

14 August 2017

1 reference

PubMed ID

16787118