(Q36148406)

12 August 2017

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title

Regulation of immunity by self-reactive T cells (English)

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12 August 2017

1

Mitchell Kronenberg

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12 August 2017

2

Alexander Rudensky

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12 August 2017

language of work or name

English

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publication date

1 June 2005

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12 August 2017

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12 August 2017

435

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12 August 2017

7042

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12 August 2017

598-604

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https://scigraph.springernature.com/pub.10.1038/nature03725

12 August 2017

0 references

cites work

Approaching the asymptote? Evolution and revolution in immunology

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Mouse CD1-specific NK1 T cells: development, specificity, and function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

CD4+ CD25+ suppressor T cells: more questions than answers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

T cell regulation as a side effect of homeostasis and competition

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Modulation of tryptophan catabolism by regulatory T cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

IDO expression by dendritic cells: tolerance and tryptophan catabolism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

An essential role for Scurfin in CD4+CD25+ T regulatory cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Peripheral autoantigen induces regulatory T cells that prevent autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Origin of regulatory T cells with known specificity for antigen

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Tolerance, not immunity, crucially depends on IL-2.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

In vivo instruction of suppressor commitment in naive T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Going both ways: immune regulation via CD1d-dependent NKT cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

NKT cells: what's in a name?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Structure-activity relationship of alpha-galactosylceramides against B16-bearing mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Toward an understanding of NKT cell biology: progress and paradoxes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Chemical structure and function of glycosphingolipids of Sphingomonas spp and their distribution among members of the alpha-4 subclass of Proteobacteria

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Recognition of bacterial glycosphingolipids by natural killer T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

NKT cells derive from double-positive thymocytes that are positively selected by CD1d

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Regulation of NKT cell development by SAP, the protein defective in XLP

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Lysosomal glycosphingolipid recognition by NKT cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Mechanism of CD1d-restricted natural killer T cell activation during microbial infection.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Natural killer T cells: natural or unnatural regulators of autoimmunity?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Cutting edge: invariant V alpha 14 NKT cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Testing the NKT cell hypothesis of human IDDM pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor beta1 production

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

The fourth way? Harnessing aggressive tendencies in the thymus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Expansion of human Valpha24+ NKT cells by repeated stimulation with KRN7000.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03725

7 January 2021

Identifiers

DOI

10.1038/NATURE03725

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Dimensions Publication ID

12 August 2017

1036265433

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Fatcat ID

release_mvbkqz7m65cdrhc3ho7bkls4ke

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mvbkqz7m65cdrhc3ho7bkls4ke

24 November 2022

mapped directly with Wikidata item

1 reference