(Q36515453)

English

Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa

scientific article published on January 2013

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa (English)

1 reference

Europe PubMed Central

14 August 2017

1 reference

based on heuristic

inferred from title

2

object named as

Basil Rapoport

1 reference

Europe PubMed Central

14 August 2017

author name string

Sandra M McLachlan

1

1 reference

Europe PubMed Central

14 August 2017

publication date

1 January 2013

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

23

1 reference

Europe PubMed Central

14 August 2017

1

1 reference

Europe PubMed Central

14 August 2017

14-24

1 reference

Europe PubMed Central

14 August 2017

Role of self-tolerance and chronic stimulation in the long-term persistence of adenovirus-induced thyrotropin receptor antibodies in wild-type and transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Changes of TSH-Stimulation Blocking Antibody (TSBAb) and Thyroid Stimulating Antibody (TSAb) Over 10 Years in 34 TSBAb-Positive Patients with Hypothyroidism and in 98 TSAb-Positive Graves' Patients with Hyperthyroidism: Reevaluation of TSBAb and TSA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Clinical course of Hashimoto's thyroiditis and effects of levothyroxine therapy on the clinical course of the disease in children and adolescents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Thyroid hormones as modulators of immune activities at the cellular level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Significance of prediagnostic thyroid antibodies in women with autoimmune thyroid disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Orbital fibrosis in a mouse model of Graves' disease induced by genetic immunization of thyrotropin receptor cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Novel chimeric thyroid-stimulating hormone-receptor bioassay for thyroid-stimulating immunoglobulins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Enhanced response to mouse thyroid-stimulating hormone (TSH) receptor immunization in TSH receptor-knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Immunoglobulin heavy chain variable region genes contribute to the induction of thyroid-stimulating antibodies in recombinant inbred mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Evidence that shed thyrotropin receptor A subunits drive affinity maturation of autoantibodies causing Graves' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

A human monoclonal autoantibody to the thyrotropin receptor with thyroid-stimulating blocking activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

TSH-receptor autoimmunity in Graves' disease after therapy with anti-thyroid drugs, surgery, or radioiodine: a 5-year prospective randomized study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Graves' animal models of Graves' hyperthyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Remission of Graves' disease during anti-thyroid drug therapy. Time to reconsider the mechanism?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Narrow individual variations in serum T(4) and T(3) in normal subjects: a clue to the understanding of subclinical thyroid disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

A new chemiluminescent assay for the rapid detection of thyroid stimulating antibodies in Graves' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Second generation assay for thyrotropin receptor antibodies has superior diagnostic sensitivity for Graves' disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Immunoglobulin G inhibitor of thyroid-stimulating antibody is a cause of delay in the onset of neonatal Graves' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Metabolic properties of IgG subclasses in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Thyroid-stimulating antibody activity between different immunoglobulin G subclasses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Three patients who spontaneously developed persistent hypothyroidism during or following treatment with antithyroid drugs for Graves' hyperthyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Hypothyroidism as a Late Sequela in Patients with Graves' Disease Treated with Antithyroid Agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Detection and Properties of TSH-Binding Inhibitor Immunoglobulins in Patients with Graves’ Disease and Hashimoto’s Thyroiditis*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

30 September 2017

Thyrotrophin receptor antibody characteristics in a woman with long-standing Hashimoto's who developed Graves' disease and pretibial myxoedema.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

Evidence for negative cooperativity among human thyrotropin receptors overexpressed in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

In Chinese hamster ovary K1 cells dog and human thyrotropin receptors activate both the cyclic AMP and the phosphatidylinositol 4,5-bisphosphate cascades in the presence of thyrotropin and the cyclic AMP cascade in its absence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

Thyroid-stimulating immunoglobulins in Graves' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

Graves' hyperthyroidism following primary hypothyroidism: sequential changes in various activities of thyrotropin receptor antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

Graves' disease following hypothyroidism due to Hashimoto's disease: studies of eight cases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

Use of the recombinant human thyrotropin receptor (TSH-R) expressed in mammalian cell lines to assay TSH-R autoantibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

The IgG subclass distribution of TSH receptor blocking antibodies in primary hypothyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

28 June 2018

Monoclonal autoantibodies to the TSH receptor, one with stimulating activity and one with blocking activity, obtained from the same blood sample

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

Elevation of serum immunoglobulin G in Hashimoto's thyroiditis and decrease after treatment with L-thyroxine in hypothyroid patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

Down-regulation of the auto-aggressive processes in patients with hypothyroid Hashimoto's thyroiditis following substitutive treatment with L-thyroxine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

Transient Graves' hyperthyroidism during pregnancy in a patient with Hashimoto's hypothyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

Affinity-enrichment of thyrotropin receptor autoantibodies from Graves' patients and normal individuals provides insight into their properties and possible origin from natural antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

Low-dose immunization with adenovirus expressing the thyroid-stimulating hormone receptor A-subunit deviates the antibody response toward that of autoantibodies in human Graves' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

Human monoclonal thyroid stimulating autoantibody.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

Evidence for a simplified view of autoantibody interactions with the thyrotropin receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

One-year prophylactic treatment of euthyroid Hashimoto's thyroiditis patients with levothyroxine: is there a benefit?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

21 September 2018

Levothyroxine in Euthyroid Autoimmune Thyroiditis and Type 1 Diabetes: A Randomized, Controlled Trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3539254

4 December 2018

A sensitive and practical assay for thyroid-stimulating antibodies using crude immunoglobulin fractions precipitated with polyethylene glycol

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A receptor assay for the measurement of TSH receptor antibodies in unextracted serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyroid hormones influence human dendritic cells' phenotype, function, and subsets distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Graves’ IgG stimulation of continuously cultured rat thyroid cells: a sensitive and potentially useful clinical assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial Neonatal Transient Hypothyroidism Due to Maternal TSH-Binding Inhibitor Immunoglobulins

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluctuating thyroid function depending on the balance between stimulating and blocking types of TSH receptor antibodies: a case report

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of regulatory capacity of CD4+CD25+ regulatory T cells mediated by dendritic cell polarization and hyperthyroidism in Graves' disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient postpartum hypothyroidism caused by thyroid-stimulation-blocking antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new in vitro assay for human thyroid stimulator using cultured thyroid cells: effect of sodium chloride on adenosine 3',5'-monophosphate increase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of serum TSH receptor autoantibody concentration and affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in stimulating and blocking TSH receptor antibodies in a patient undergoing three cycles of transition from hypo to hyper-thyroidism and back to hypothyroidism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human thyroid adenyl cyclase-stimulating activity in immunoglobulin G of patients with Graves' disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of spontaneous hypothyroidism in patients with Graves' disease after antithyroid drug treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient neonatal hypothyroidism: characterization of maternal antibodies to the thyrotropin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the levels of TSH-binding inhibitor immunoglobulins in goitrous and agoitrous autoimmune thyroiditis after twelve months of L-thyroxine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyroid-stimulating immunoglobulin bioassay using cultured human thyroid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A change from stimulatory to blocking antibody activity in Graves' disease during pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbimazole and the Autoimmune Response in Graves' Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-thyroxine therapy induces a fall of thyroid microsomal and thyroglobulin antibodies in idiopathic myxedema and in hypothyroid, but not in euthyroid Hashimoto's thyroiditis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive transfer of antithyrotropin receptor (TSHR) autoimmunity from TSHR knockout mice to athymic nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyroid-stimulating antibody (TSab) detected in sera of Graves' patients using human thyroid cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of spontaneous hypothyroidism in patients with Graves' disease treated with antithyroidal drugs: clinical, immunological, and histological findings in 26 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of hyperthyroidism following primary hypothyroidism: a case report with changes in thyroid-related antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of fragments with thyroid stimulating activity from thyroid stimulation blocking antibodies-IgG molecules by papain digestion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of thyroid-stimulating hormone receptor autoantibodies by ELISA

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TSH receptor antibody (TRAb) assays based on the human monoclonal autoantibody M22 are more sensitive than bovine TSH based assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/23025526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/THY.2012.0374

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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