(Q36520715)

English

Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma

scientific article published on December 2012

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma (English)

1 reference

Europe PubMed Central

14 August 2017

author name string

Xiaosong Wu

1

1 reference

Europe PubMed Central

14 August 2017

Yi Tao

2

1 reference

Europe PubMed Central

14 August 2017

Jun Hou

3

1 reference

Europe PubMed Central

14 August 2017

Xiuqin Meng

4

1 reference

Europe PubMed Central

14 August 2017

Jumei Shi

5

1 reference

Europe PubMed Central

14 August 2017

publication date

1 December 2012

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

14

1 reference

Europe PubMed Central

14 August 2017

12

1 reference

Europe PubMed Central

14 August 2017

1178-1189

1 reference

Europe PubMed Central

14 August 2017

Latest advances and current challenges in the treatment of multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Cancer immunotherapy comes of age

1 reference

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30 September 2017

Treatment strategies in relapsed and refractory multiple myeloma: a focus on drug sequencing and 'retreatment' approaches in the era of novel agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Upregulation of NKG2D ligands and enhanced natural killer cell cytotoxicity by hydralazine and valproate.

1 reference

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Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis

1 reference

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Natural killer cell activity and killer immunoglobulin-like receptors in hematopoietic stem cell transplantation

1 reference

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30 September 2017

Proteasome regulation of ULBP1 transcription

1 reference

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30 September 2017

Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysis

1 reference

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Activation of the neuronal extracellular signal-regulated kinase 2 in the spinal cord dorsal horn is required for complete Freund's adjuvant-induced pain hypersensitivity

1 reference

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30 September 2017

Resistance to cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cells

1 reference

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The anticancer immune response: indispensable for therapeutic success?

1 reference

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30 September 2017

NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy

1 reference

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30 September 2017

The NKG2D receptor: sensing stressed cells

1 reference

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30 September 2017

Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance.

1 reference

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30 September 2017

Immunological aspects of cancer chemotherapy

1 reference

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30 September 2017

NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Tumor stress, cell death and the ensuing immune response.

1 reference

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30 September 2017

Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B ligands of NKG2D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Expression and role of MHC class I-related chain in myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Transcriptional regulation of ULBP1, a human ligand of the NKG2D receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

BCR/ABL oncogene directly controls MHC class I chain-related molecule A expression in chronic myelogenous leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

NKG2D ligands are expressed on stressed human airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Immunobiology of human NKG2D and its ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

NKG2D function protects the host from tumor initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway

1 reference

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30 September 2017

NF-kappa B regulates expression of the MHC class I-related chain A gene in activated T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.

1 reference

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30 September 2017

Ovarian carcinoma expresses the NKG2D ligand Letal and promotes the survival and expansion of CD28- antitumor T cells

1 reference

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30 September 2017

Stress management: MHC class I and class I-like molecules as reporters of cellular stress

1 reference

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30 September 2017

Roles of the NKG2D immunoreceptor and its ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

30 September 2017

Anti-tumor mechanisms of valproate: a novel role for an old drug

1 reference

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Binding of Escherichia coli adhesin AfaE to CD55 triggers cell-surface expression of the MHC class I-related molecule MICA

1 reference

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30 September 2017

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

1 reference

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30 September 2017

Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells

1 reference

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30 September 2017

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

1 reference

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30 September 2017

Human CD16 as a lysis receptor mediating direct natural killer cell cytotoxicity

1 reference

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Antitumor activity of sodium valproate in cultures of human neuroblastoma cells.

1 reference

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Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate

1 reference

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21 September 2018

ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes.

1 reference

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Nfl gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways

1 reference

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21 September 2018

Expression of the stress-related MHC class I chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients.

1 reference

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21 September 2018

Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540943

21 September 2018

PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways

1 reference

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21 September 2018

Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory

1 reference

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Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK- cell lysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23308050

12 December 2020

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Identifiers

10.1593/NEO.121236

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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