(Q36521099)

English

Ablation of the Stimulatory G Protein α-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D.

scientific article published on 15 December 2015

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PMC publication ID

14 August 2017

Ablation of the Stimulatory G Protein α-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D. (English)

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14 August 2017

Isabelle Rubera

4

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9 June 2020

5

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9 June 2020

Lee S. Weinstein

7

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9 June 2020

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Murat Bastepe

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9 June 2020

Harald Jüppner

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Harald Jüppner

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9 June 2020

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Yan Zhu

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9 June 2020

Qing He

2

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9 June 2020

Cumhur Aydin

3

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9 June 2020

Min Chen

6

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9 June 2020

Vladimir Marshansky

8

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9 June 2020

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15 December 2015

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14 August 2017

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11

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9 June 2020

157

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9 June 2020

2

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9 June 2020

497-507

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9 June 2020

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11 June 2022

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Evidence of hormone resistance in a pseudo-pseudohypoparathyroidism patient with a novel paternal mutation in GNAS.

1 reference

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1 reference

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Postnatal establishment of allelic Gαs silencing as a plausible explanation for delayed onset of parathyroid hormone resistance owing to heterozygous Gαs disruption

1 reference

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Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute responses to PTH

1 reference

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Activation of a non-cAMP/PKA signaling pathway downstream of the PTH/PTHrP receptor is essential for a sustained hypophosphatemic response to PTH infusion in male mice

1 reference

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Genetics and epigenetics of parathyroid hormone resistance

1 reference

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An update on the clinical and molecular characteristics of pseudohypoparathyroidism.

1 reference

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30 September 2017

Loss of XLαs (extra-large αs) imprinting results in early postnatal hypoglycemia and lethality in a mouse model of pseudohypoparathyroidism Ib.

1 reference

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30 September 2017

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PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice

1 reference

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30 September 2017

Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo

1 reference

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30 September 2017

Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo

1 reference

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30 September 2017

Acute Down-regulation of Sodium-dependent Phosphate Transporter NPT2a Involves Predominantly the cAMP/PKA Pathway as Revealed by Signaling-selective Parathyroid Hormone Analogs

1 reference

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30 September 2017

Is caveolin involved in normal proximal tubule function? Presence in model PT systems but absence in situ.

1 reference

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30 September 2017

PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop

1 reference

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30 September 2017

Acute parathyroid hormone differentially regulates renal brush border membrane phosphate cotransporters

1 reference

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30 September 2017

Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib

1 reference

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Progressive osseous heteroplasia: a model for the imprinting effects of GNAS inactivating mutations in humans

1 reference

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30 September 2017

Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts

1 reference

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30 September 2017

Recent advances in renal phosphate handling

1 reference

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30 September 2017

Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23.

1 reference

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A global double-fluorescent Cre reporter mouse

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Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice

1 reference

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30 September 2017

Alternative Gnas gene products have opposite effects on glucose and lipid metabolism.

1 reference

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30 September 2017

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

1 reference

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30 September 2017

Regulation of the murine renal vitamin D receptor by 1,25-dihydroxyvitamin D3 and calcium

1 reference

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30 September 2017

Parathyroid hormone regulates 25-hydroxyvitamin D(3)-24-hydroxylase mRNA by altering its stability

1 reference

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30 September 2017

Endocrine manifestations of stimulatory G protein alpha-subunit mutations and the role of genomic imprinting

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Positive and negative regulations of the renal 25-hydroxyvitamin D3 1alpha-hydroxylase gene by parathyroid hormone, calcitonin, and 1alpha,25(OH)2D3 in intact animals

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Variable and tissue-specific hormone resistance in heterotrimeric Gs protein alpha-subunit (Gsalpha) knockout mice is due to tissue-specific imprinting of the gsalpha gene

1 reference

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Pseudohypoparathyroidism: defective excretion of 3',5'-AMP in response to parathyroid hormone

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In VivoEvidence for the Intermediary Role of 3′,5′-Cyclic AMP in Parathyroid Hormone-Induced Stimulation of lα,25-Dihydroxy vitamin D3Synthesis in Rats

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1 reference

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12 December 2020

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2015-1639

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26671181%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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Europe PubMed Central

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9 June 2020

PubMed publication ID

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Europe PubMed Central

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9 June 2020

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