(Q36527252)

English

Comparative computational analysis of prion proteins reveals two fragments with unusual structural properties and a pattern of increase in hydrophobicity associated with disease-promoting mutations

scientific article published on December 2004

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Comparative computational analysis of prion proteins reveals two fragments with unusual structural properties and a pattern of increase in hydrophobicity associated with disease-promoting mutations (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

prion protein family

0 references

1 reference

based on heuristic

inferred from title

computational biology

1 reference

based on heuristic

inferred from title

author name string

Igor B Kuznetsov

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Shalom Rackovsky

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 December 2004

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Protein Science

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

3230-3244

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

On the properties and sequence context of structurally ambivalent fragments in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

NMR structure of the human doppel protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Mutations of the prion protein gene phenotypic spectrum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Molecular dynamics simulations of alanine rich beta-sheet oligomers: Insight into amyloid formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Structural studies of the scrapie prion protein by electron crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Crystal structure of the human prion protein reveals a mechanism for oligomerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Two different neurodegenerative diseases caused by proteins with similar structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

NMR structure of the bovine prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Application of multiple sequence alignment profiles to improve protein secondary structure prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Conformational transitions in model silk peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

NMR solution structure of the human prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Evidence for the role of PrP(C) helix 1 in the hydrophilic seeding of prion aggregates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Predicting conformational switches in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Trafficking of the cellular isoform of the prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Is protein folding hierarchic? I. Local structure and peptide folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Prion protein NMR structure and familial human spongiform encephalopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Prion Protein Biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Identification and application of the concepts important for accurate and reliable protein secondary structure prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Comparison of circumsporozoite proteins from avian and mammalian malarias: biological and phylogenetic implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Cell biology of the prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Combining evolutionary information and neural networks to predict protein secondary structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Proposed three-dimensional structure for the cellular prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Comparison of systematic search and database methods for constructing segments of protein structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Solvation energy in protein folding and binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Amino acid substitution matrices from protein blocks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

Selection of representative protein data sets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

30 September 2017

The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

28 June 2018

Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

28 June 2018

Similarity between the C-terminal domain of the prion protein and chimpanzee cytomegalovirus glycoprotein UL9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC-->PrPSc conversion process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Loopy proteins appear conserved in evolution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Intramolecular versus intermolecular disulfide bonds in prion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Prediction of amyloid fibril-forming proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Familial mutations and the thermodynamic stability of the recombinant human prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Removing near-neighbour redundancy from large protein sequence collections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Exploring the folding pathways of annexin I, a multidomain protein. II. Hierarchy in domain folding propensities may govern the folding process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Prion proteins: evolution and preservation of secondary structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Scrapie prions: a three-dimensional model of an infectious fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Incorporation of non-local interactions in protein secondary structure prediction from the amino acid sequence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

GOR method for predicting protein secondary structure from amino acid sequence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Prion protein peptides induce alpha-helix to beta-sheet conformational transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Intrinsic phi, psi propensities of amino acids, derived from the coil regions of known structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Conformational transitions in peptides containing two putative alpha-helices of the prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 September 2018

Most of the structural elements of the globular domain of murine prion protein form fibrils with predominant beta-sheet structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 October 2018

Polypeptide chain folding in the hydrophobic core of hamster scrapie prion: analysis by X-ray diffraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2287303

21 October 2018

Neighboring base effects on substitution rates in pseudogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15557265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrophobicity and structural classes in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15557265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimized representations and maximal information in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15557265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptides and proteins in neurodegenerative disease: helix propensity of a polypeptide containing helix 1 of the mouse prion protein studied by NMR and CD spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15557265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid side chain parameters for correlation studies in biology and pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/15557265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra

1 reference

https://pubmed.ncbi.nlm.nih.gov/15557265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Context-dependent secondary structure formation of a designed protein sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/15557265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1110/PS.04833404

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

0 references

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