(Q36527927)

14 August 2017

Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness (English)

1 reference

14 August 2017

8

Valerie Speirs

0 references

Andrew M. Hanby

7

Andrew M Hanby

1 reference

14 August 2017

Alexandra Avgustinova

Alexandra Avgustinova

1

0 references

Fernando Calvo

Fernando Calvo

10

0 references

Erik Sahai

Erik Sahai

9

0 references

Clare M Isacke

Clare M Isacke

11

0 references

author name string

Marjan Iravani

2

1 reference

14 August 2017

David Robertson

3

1 reference

14 August 2017

Antony Fearns

4

1 reference

14 August 2017

Qiong Gao

5

1 reference

14 August 2017

Pamela Klingbeil

6

1 reference

14 August 2017

language of work or name

English

0 references

publication date

18 January 2016

1 reference

full work available at URL

14 August 2017

http://eprints.whiterose.ac.uk/94087

content deliverer

White Rose Research Online

copyright license

Creative Commons Attribution 4.0 International

object has role

published version

1 reference

White Rose Research Online

http://eprints.whiterose.ac.uk/94087

15 December 2018

published in

Nature Communications

1 reference

14 August 2017

7

1 reference

14 August 2017

10305

1 reference

Creative Commons Attribution 4.0 International

14 August 2017

start time

18 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4735631

inferred from PubMed Central ID database lookup

cites work

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Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

30 September 2017

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30 September 2017

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LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1.

30 September 2017

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Fibronectin regulates Wnt7a signaling and satellite cell expansion

30 September 2017

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Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts

30 September 2017

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Low ERK phosphorylation in cancer-associated fibroblasts is associated with tamoxifen resistance in pre-menopausal breast cancer

30 September 2017

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Symmetric expansion of neural stem cells from the adult olfactory bulb is driven by astrocytes via WNT7A.

30 September 2017

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Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury

30 September 2017

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Clinical and functional significance of loss of caveolin-1 expression in breast cancer-associated fibroblasts

30 September 2017

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Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

30 September 2017

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Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

30 September 2017

1 reference

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WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/β-catenin pathway.

30 September 2017

1 reference

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Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression

30 September 2017

1 reference

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Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca²⁺/Calmodulin-dependent protein kinase II

30 September 2017

1 reference

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Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

30 September 2017

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PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer

30 September 2017

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Hallmarks of cancer: interactions with the tumor stroma.

30 September 2017

1 reference

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Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer

30 September 2017

1 reference

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Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells

30 September 2017

1 reference

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Stromal myofibroblasts are drivers of invasive cancer growth

30 September 2017

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Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis

30 September 2017

1 reference

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Cancer as an overhealing wound: an old hypothesis revisited

30 September 2017

1 reference

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Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells

30 September 2017

1 reference

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Stromal gene expression predicts clinical outcome in breast cancer

30 September 2017

1 reference

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Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Endosialin (CD248) is a marker of tumor-associated pericytes in high-grade glioma

30 September 2017

1 reference

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30 September 2017

Fibroblasts in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy

30 September 2017

1 reference

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Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Wnt-7a up-regulates matrix metalloproteinase-12 expression and promotes cell proliferation in corneal epithelial cells during wound healing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

30 September 2017

1 reference

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Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.

30 September 2017

1 reference

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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

30 September 2017

1 reference

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TGFbeta and Wnt pathway cross-talk

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

30 September 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

p180, a novel recycling transmembrane glycoprotein with restricted cell type expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Signal integration in TGF-β, WNT, and Hippo pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor: heterogeneity in phenotypic stability.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Inhibition of lung colonization at two different steps in the metastatic sequence

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Counteracting stem cell expansion during wound repair: distinct roles of non-canonical Wnt and TGF-β.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Noncanonical WNT-5A signaling regulates TGF-β-induced extracellular matrix production by airway smooth muscle cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Endosialin is expressed on stromal fibroblasts and CNS pericytes in mouse embryos and is downregulated during development.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Profiling molecular targets of TGF-beta1 in prostate fibroblast-to-myofibroblast transdifferentiation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Syndecan-4 deficiency leads to high mortality of lipopolysaccharide-injected mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4735631

Observation of Antigen-Dependent CD8+ T-Cell/ Dendritic Cell Interactions in Vivo

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS10305

21 January 2018

1 reference

12 December 2020

Prognostic value of desmoplastic reaction and lymphocytic infiltration in the management of breast cancer

1 reference

PubMed

12 December 2020

Focus issue: an expanding world for TGF-beta signaling

1 reference

PubMed

12 December 2020

Identification of fibroblast heterogeneity in the tumor microenvironment

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1038/NCOMMS10305

1 reference

Dimensions Publication ID

14 August 2017

0 references

0 references

0 references

0 references

1 reference

14 August 2017

PubMed publication ID

26777421

1 reference