(Q36528125)

14 August 2017

Engineering multiple properties of a protein by combinatorial mutagenesis (English)

1 reference

14 August 2017

Sandberg WS

1

1 reference

14 August 2017

Terwilliger TC

series ordinal

2

1 reference

14 August 2017

language of work or name

English

0 references

publication date

1 September 1993

1 reference

14 August 2017

5

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

14 August 2017

90

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14 August 2017

18

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14 August 2017

8367-8371

1 reference

Fluorescence studies of the complex formation between the gene 5 protein of bacteriophage M13 and polynucleotides

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Designing substrate specificity by protein engineering of electrostatic interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Functional role of aspartic acid-27 in dihydrofolate reductase revealed by mutagenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Stabilization of lambda repressor against thermal denaturation by site-directed Gly----Ala changes in alpha-helix 3.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Disulfide bonds and thermal stability in T4 lysozyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Construction of a synthetic variant of the bacteriophage f1 gene V by assembling oligodeoxynucleotides corresponding to only one strand of DNA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Isolation of a thermostable enzyme variant by cloning and selection in a thermophile

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Hydrophobic packing in T4 lysozyme probed by cavity-filling mutants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Contributions of the large hydrophobic amino acids to the stability of staphylococcal nuclease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Isolation and in vitro characterization of temperature-sensitive mutants of the bacteriophage f1 gene V protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Energetics of repacking a protein interior

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Toward a simplification of the protein folding problem: a stabilizing polyalanine alpha-helix engineered in T4 lysozyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

A new way of enhancing the thermostability of proteases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Binding of IKe gene 5 protein to polynucleotides. Fluorescence binding experiments of IKe gene 5 protein and mutual cooperativity of IKe and M13 gene 5 proteins.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Dissecting the catalytic triad of a serine protease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Lambda repressor mutations that increase the affinity and specificity of operator binding.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Cumulative effect of intragenic amino-acid replacements on the thermostability of a protein

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Influence of interior packing and hydrophobicity on the stability of a protein.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Energetics of complementary side-chain packing in a protein hydrophobic core

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Engineering subtilisin BPN' for site-specific proteolysis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Additivity of mutational effects in proteins

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Reversible denaturation of the gene V protein of bacteriophage f1.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Simple and highly efficient site-specific mutagenesis, by ligation of an oligodeoxyribonucleotide into gapped heteroduplex DNA in which the template strand contains deoxyuridine

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Engineering enzyme specificity by "substrate-assisted catalysis"

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47357

Fine structure of a membrane anchor domain

21 October 2018

1 reference

12 December 2020

Rational modification of enzyme catalysis by engineering surface charge

1 reference

12 December 2020

Proteases of enhanced stability: characterization of a thermostable variant of subtilisin

1 reference

12 December 2020

Contribution of hydrophobic interactions to protein stability

1 reference

12 December 2020

Identification of residues involved in a conformational change accompanying substitutions for glutamate-43 in staphylococcal nuclease

1 reference

12 December 2020

Combining thermostable mutations increases the stability of lambda repressor

1 reference

12 December 2020

The crystallographically determined structures of atypical strained disulfides engineered into subtilisin

1 reference

12 December 2020

Substantial increase of protein stability by multiple disulphide bonds

1 reference

12 December 2020

Specificity of the binding of bacteriophage M13 encoded gene-5 protein to DNA and RNA studied by means of fluorescence titrations

1 reference

12 December 2020

A mutant T4 lysozyme (Val 131----Ala) designed to increase thermostability by the reduction of strain within an alpha-helix

1 reference

12 December 2020

Sequence-specific 1H-NMR assignment and secondary structure of the Tyr41----His mutant of the single-stranded DNA binding protein, gene V protein, encoded by the filamentous bacteriophage M13

1 reference

12 December 2020

Gene V protein of fd bacteriophage. Dimer formation and the role of tyrosyl groups in DNA binding

1 reference

12 December 2020

Interaction of gene 5 protein of phage f1 with single and double-stranded DNA and polynucleotides

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.90.18.8367

1 reference

14 August 2017

0 references

1 reference

14 August 2017

PubMed publication ID

8378307

1 reference