(Q36533472)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

review article

1 reference

title

Bryostatin-1: pharmacology and therapeutic potential as a CNS drug (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

ChEBI release 2020-05-28

Miao-Kun Sun

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Daniel L Alkon

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

publication date

1 January 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

CNS Neuroscience & Therapeutics

26 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

1-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

Signal transduction abnormalities in melancholic depression

26 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Sensitization of human breast cancer cells to gemcitabine by the protein kinase C modulator bryostatin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Time domains of neuronal Ca2+ signaling and associative memory: steps through a calexcitin, ryanodine receptor, K+ channel cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

The clinical development of the bryostatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

A phase II trial of bryostatin-1 administered by weekly 24-hour infusion in recurrent epithelial ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Bryostatin-1 and IL-2 synergize to induce IFN-gamma expression in human peripheral blood T cells: implications for cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Bryostatin 1, a novel antineoplastic agent and protein kinase C activator, induces human myalgia and muscle metabolic defects: a 31P magnetic resonance spectroscopic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Protein kinase C isozymes as potential targets for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

A phase I trial of bryostatin 1 in patients with advanced malignancy using a 24 hour intravenous infusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Conventional protein kinase C (PKC)-alpha and novel PKC epsilon, but not -delta, increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Amyloid beta peptide directly inhibits PKC activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Bryostatin 1 induces biphasic activation of protein kinase D in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Chemistry and clinical biology of the bryostatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Phase II trial of the combination of bryostatin-1 and cisplatin in advanced or recurrent carcinoma of the cervix: a New York Gynecologic Oncology Group study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Imipramine and citalopram facilitate amyloid precursor protein secretion in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Altered expression and phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) in postmortem brain of suicide victims with or without depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Decreased catalytic activity and expression of protein kinase C isozymes in teenage suicide victims: a postmortem brain study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Isolation and structure of bryostatin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Phosphorylation and regulation of antidepressant-sensitive serotonin transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

PKC-independent modulation of multidrug resistance in cells with mutant (V185) but not wild-type (G185) P-glycoprotein by bryostatin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Dual effects of bryostatin-1 on spatial memory and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Protein kinase C isozymes: memory therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

The practical synthesis of a novel and highly potent analogue of bryostatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Blockade of PKC epsilon activation attenuates phorbol ester-induced increase of alpha-secretase-derived secreted form of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Validation and implementation of a method for determination of bryostatin 1 in human plasma by using liquid chromatography/tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Protein kinase C epsilon suppresses Abeta production and promotes activation of alpha-secretase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2006.00001.X

Regulation of glycogen synthase in rat hepatocytes. Evidence for multiple signaling pathways

21 January 2018

1 reference

12 December 2020

A Phase I trial of bryostatin-1 in children with refractory solid tumors: a Pediatric Oncology Group study.

1 reference

12 December 2020

A role for the beta isoform of protein kinase C in fear conditioning.

1 reference

12 December 2020

Depressed or demented: common CNS drug targets?!

1 reference

12 December 2020

Phase I and correlative study of combination bryostatin 1 and vincristine in relapsed B-cell malignancies.

1 reference

12 December 2020

Identification of a tunable site in bryostatin analogs: C20 Bryologs through late stage diversification

1 reference

12 December 2020

Role of the A-ring of bryostatin analogues in PKC binding: synthesis and initial biological evaluation of new A-ring-modified bryologs

1 reference

12 December 2020

Decreased levels of protein kinase C in Alzheimer brain

1 reference

12 December 2020

Demonstration of sub-nanomolar affinity of bryostatin 1 for the phorbol ester receptor in rat brain

1 reference

12 December 2020

Differing modulation of protein kinase C by bryostatin 1 and phorbol esters in JB6 mouse epidermal cells

1 reference

12 December 2020

Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin

1 reference

12 December 2020

The bryostatins inhibit growth of B16/F10 melanoma cells in vitro through a protein kinase C-independent mechanism: dissociation of activities using 26-epi-bryostatin 1.

1 reference

12 December 2020

Preclinical pharmacology of the natural product anticancer agent bryostatin 1, an activator of protein kinase C.

1 reference

12 December 2020

Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain

1 reference

12 December 2020

Possible role of protein kinase C in regulation of 5-hydroxytryptamine 2A receptors in rat brain

1 reference

12 December 2020

Bryostatin 1 down-regulates mdr1 and potentiates vincristine cytotoxicity in diffuse large cell lymphoma xenografts.

1 reference

12 December 2020

10.1111/J.1527-3458.2006.00001.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16834754%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

PubMed publication ID

16834754

1 reference