(Q36535760)

14 August 2017

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title

The role of virus-induced regulatory T cells in immunopathology (English)

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14 August 2017

2

Kim J Hasenkrug

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14 August 2017

Shelly J Robertson

1

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PubMed ID

16841143

14 August 2017

language of work or name

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14 July 2006

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Seminars in Immunopathology

14 August 2017

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14 August 2017

28

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14 August 2017

51-62

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14 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s00281-006-0019-2

14 August 2017

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cites work

CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions.

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

CD4+ Tregs and immune control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Regulatory cells and infectious agents: detentes cordiale and contraire

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Cutting edge: pulmonary immunopathology mediated by antigen-specific expression of TNF-alpha by antiviral CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

The spectrum of severe acute respiratory syndrome-associated coronavirus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Regulation of murine inflammatory bowel disease by CD25+ and CD25- CD4+ glucocorticoid-induced TNF receptor family-related gene+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Cross-linking of CD45 on suppressive/regulatory T cells leads to the abrogation of their suppressive activity in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

In vitro suppression of CD8+ T cell function by Friend virus-induced regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Timed ablation of regulatory CD4+ T cells can prevent murine AIDS progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Peptide specificity of thymic selection of CD4+CD25+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Antigen-specific T cell repertoire modification of CD4+CD25+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Feline immunodeficiency virus infection phenotypically and functionally activates immunosuppressive CD4+CD25+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Depletion of regulatory T cells in HIV infection is associated with immune activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Hepatic expansion of a virus-specific regulatory CD8+ T cell population in chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0019-2

Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

21 January 2018

1 reference

12 December 2020

Analysis of successful immune responses in persons infected with hepatitis C virus

1 reference

12 December 2020

T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

1 reference

12 December 2020

Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging

1 reference

12 December 2020

HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells

1 reference

12 December 2020

Cell interactions in the induction of tolerance: the role of thymic lymphocytes

1 reference

12 December 2020

High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys

1 reference

12 December 2020

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

1 reference

12 December 2020

Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI.

1 reference

12 December 2020

Preferential feline immunodeficiency virus (FIV) infection of CD4+ CD25+ T-regulatory cells correlates both with surface expression of CXCR4 and activation of FIV long terminal repeat binding cellular transcriptional factors

1 reference

12 December 2020

Modulation of tryptophan catabolism by regulatory T cells.

1 reference

12 December 2020

CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status

1 reference

12 December 2020

Direct ex vivo kinetic and phenotypic analyses of CD8(+) T-cell responses induced by DNA immunization

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12 December 2020

Inducing and expanding regulatory T cell populations by foreign antigen

1 reference

12 December 2020

Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8 T cell-mediated, TNF-dependent immunopathology

1 reference

12 December 2020

Differential CD4(+) and CD8(+) T-cell responsiveness in hepatitis C virus infection

1 reference

12 December 2020

Analysis of a successful immune response against hepatitis C virus

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12 December 2020

Impairment of CD4(+)CD25(+) regulatory T-cells in autoimmune liver disease.

1 reference

12 December 2020

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

1 reference

12 December 2020

Predominance of type 1 (Th1) cytokine production in the liver of patients with HCV-associated mixed cryoglobulinemia vasculitis.

1 reference

12 December 2020

Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process

1 reference

12 December 2020

Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

1 reference

12 December 2020

Control of immune responses by naturally arising CD4+ regulatory T cells that express toll-like receptors

1 reference

12 December 2020

Differentiation of T regulatory cells by immature dendritic cells

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12 December 2020

Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation

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12 December 2020

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

1 reference

12 December 2020

TCRalphabeta repertoire diversity of human naturally occurring CD4+CD25+ regulatory T cells.

1 reference

12 December 2020

Characterization of novel HLA-DR11-restricted HCV epitopes reveals both qualitative and quantitative differences in HCV-specific CD4+ T cell responses in chronically infected and non-viremic patients

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12 December 2020

Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

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12 December 2020

CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion

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12 December 2020

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

1 reference

12 December 2020

Possible origin of adult T-cell leukemia/lymphoma cells from human T lymphotropic virus type-1-infected regulatory T cells

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12 December 2020

Interleukin-10 and the interleukin-10 receptor

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12 December 2020

Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis

1 reference

12 December 2020

Recruitment times, proliferation, and apoptosis rates during the CD8(+) T-cell response to lymphocytic choriomeningitis virus

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12 December 2020

Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection

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12 December 2020

Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues

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12 December 2020

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

1 reference

12 December 2020

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

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12 December 2020

Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors

1 reference

12 December 2020

Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients

1 reference

12 December 2020

The paradox of simian immunodeficiency virus infection in sooty mangabeys: active viral replication without disease progression

1 reference

12 December 2020

Origin of regulatory T cells with known specificity for antigen

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12 December 2020

Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

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12 December 2020

Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection.

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12 December 2020

1 reference

12 December 2020

Immunosuppression by CD4+ regulatory T cells induced by chronic retroviral infection

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12 December 2020

Molecular analysis of the hotspot of recombination in the murine major histocompatibility complex.

1 reference

12 December 2020

CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1.

1 reference

12 December 2020

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

1 reference

12 December 2020

Productive human immunodeficiency virus-1 infection of megakaryocytic cells is enhanced by tumor necrosis factor-alpha

1 reference

12 December 2020

CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes

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12 December 2020

Natural regulatory T cells in infectious disease

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12 December 2020

Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance

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12 December 2020

Foxp3: a critical regulator of the development and function of regulatory T cells

1 reference

12 December 2020

Peripheral generation and function of CD4+CD25+ regulatory T cells

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12 December 2020

Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance

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12 December 2020

Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

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12 December 2020

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

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12 December 2020

T cell activation and disease severity in HIV infection

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12 December 2020

The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells

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12 December 2020

Broad Specificity of Virus-Specific CD4+ T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection

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12 December 2020

CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons

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12 December 2020

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

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12 December 2020

Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects

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12 December 2020

T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections

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12 December 2020

An essential role for Scurfin in CD4+CD25+ T regulatory cells

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12 December 2020

Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma

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12 December 2020

HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation

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12 December 2020

Compromised lymphocytes infiltrate hepatocellular carcinoma: the role of T-regulatory cells

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12 December 2020

Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.

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12 December 2020

Regulatory T cells in the control of immune pathology.

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12 December 2020

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

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12 December 2020

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals

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12 December 2020

Pathologic features of lung biopsy specimens from influenza pneumonia cases

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12 December 2020

Regulation of murine chronic colitis by CD4+CD25- programmed death-1+ T cells

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12 December 2020

Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C

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12 December 2020

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

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12 December 2020

Control of regulatory T cell development by the transcription factor Foxp3

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12 December 2020

TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes

1 reference

12 December 2020

CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses

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12 December 2020

Whither T-suppressors: if they didn't exist would we have to invent them?

1 reference

12 December 2020

Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection

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12 December 2020

The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen

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12 December 2020

Mechanisms of suppression by suppressor T cells

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12 December 2020

CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?

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12 December 2020

Role of the specific T-cell response for clearance and control of hepatitis C virus

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12 December 2020

CD8+ T-cell dysfunction due to cytolytic granule deficiency in persistent Friend retrovirus infection

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12 December 2020

Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

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12 December 2020

Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection.

1 reference

12 December 2020

Quantitative and qualitative assessment of human immunodeficiency virus type 1 (HIV-1)-specific CD4+ T cell immunity to gag in HIV-1-infected individuals with differential disease progression: reciprocal interferon-gamma and interleukin-10 responses

1 reference

12 December 2020

IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

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12 December 2020

Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with hepatitis B virus infection

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12 December 2020

CD4(+) CD25(+) regulatory T cell selection

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12 December 2020

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

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12 December 2020

Cytopathic killing of peripheral blood CD4(+) T lymphocytes by human immunodeficiency virus type 1 appears necrotic rather than apoptotic and does not require env.

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12 December 2020

Cell mediated immune response to the hepatitis C virus.

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12 December 2020

Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection

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12 December 2020

Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens

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12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

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12 December 2020

Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift

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12 December 2020

Recovery from a viral respiratory infection. I. Influenza pneumonia in normal and T-deficient mice

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12 December 2020

Virus-stimulated plasmacytoid dendritic cells induce CD4+ cytotoxic regulatory T cells

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12 December 2020

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

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12 December 2020

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

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12 December 2020

Effect of CD4+ CD25+ regulatory T-cells on CD8 T-cell function in patients with autoimmune hepatitis

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12 December 2020

IL-10-producing T cells suppress immune responses in anergic tuberculosis patients

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12 December 2020

Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers

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12 December 2020

Regulatory T cells are expanded in blood and disease sites in patients with tuberculosis

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12 December 2020

Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussi

1 reference

12 December 2020

An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

1 reference

12 December 2020

CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis.

1 reference

12 December 2020

Regulatory T cells: friend or foe in immunity to infection?

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12 December 2020

Identification of a CD4+CD25+ T?cell subset committedin vivoto suppress antigen-specific T?cell responses without additional stimulation

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12 December 2020

Low levels of perforin expression in CD8+ T lymphocyte granules in lymphoid tissue during acute human immunodeficiency virus type 1 infection

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12 December 2020

Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection

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12 December 2020

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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12 December 2020

Pre-seroconversion immune status predicts the rate of CD4 T cell decline following HIV infection.

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12 December 2020

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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12 December 2020

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

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12 December 2020

Circulating CD8 T lymphocytes in human immunodeficiency virus-infected individuals have impaired function and downmodulate CD3 zeta, the signaling chain of the T-cell receptor complex.

1 reference

12 December 2020

10.1007/S00281-006-0019-2

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16841143