(Q36543668)

English

Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition

scientific article published on 27 November 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Leland W K Chung

12

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Leland W K Chung

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Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Shumin Zhang

1

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14 August 2017

Xu Wang

2

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14 August 2017

Shareen Iqbal

3

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14 August 2017

Yanru Wang

4

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14 August 2017

Adeboye O Osunkoya

5

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14 August 2017

Zhengjia Chen

6

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14 August 2017

Zhuo Chen

7

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14 August 2017

Dong M Shin

8

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14 August 2017

Hongwei Yuan

9

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14 August 2017

Yongqiang A Wang

10

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14 August 2017

Haiyen E Zhau

11

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14 August 2017

Chad Ritenour

13

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14 August 2017

Omer Kucuk

14

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14 August 2017

Daqing Wu

15

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14 August 2017

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publication date

27 November 2012

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14 August 2017

Journal of Biological Chemistry

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14 August 2017

288

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14 August 2017

3

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Europe PubMed Central

PMC publication ID

14 August 2017

1469-1479

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Europe PubMed Central

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14 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3548460/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548460

30 September 2017

EPLIN is a negative regulator of prostate cancer growth and invasion

1 reference

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β2-microglobulin induces epithelial to mesenchymal transition and confers cancer lethality and bone metastasis in human cancer cells

1 reference

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Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer

1 reference

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TGFβ and EGF synergistically induce a more invasive phenotype of epithelial ovarian cancer cells

1 reference

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Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells

1 reference

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ErbB/EGF signaling and EMT in mammary development and breast cancer

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Epithelial Protein Lost in Neoplasm alpha (Eplin-alpha) is transcriptionally regulated by G-actin and MAL/MRTF coactivators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548460

30 September 2017

Targeting proteins for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548460

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Global gene expression analysis of reactive stroma in prostate cancer.

1 reference

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EGFR ligand switch in late stage prostate cancer contributes to changes in cell signaling and bone remodeling

1 reference

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Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome.

1 reference

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30 September 2017

EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt

1 reference

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30 September 2017

Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins

1 reference

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30 September 2017

Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression

1 reference

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30 September 2017

Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation.

1 reference

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30 September 2017

Extracellular signal-regulated kinase/mitogen-activated protein kinase regulates actin organization and cell motility by phosphorylating the actin cross-linking protein EPLIN

1 reference

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Understanding metastatic SCCHN cells from unique genotypes to phenotypes with the aid of an animal model and DNA microarray analysis

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Prostate cancer metastasis: role of the host microenvironment in promoting epithelial to mesenchymal transition and increased bone and adrenal gland metastasis

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30 September 2017

Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice

1 reference

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The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

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Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies

1 reference

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30 September 2017

Expression of the epidermal growth factor receptor family in prostate carcinoma before and during androgen-independence

1 reference

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30 September 2017

Reactive stroma as a predictor of biochemical-free recurrence in prostate cancer

1 reference

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30 September 2017

New advances on prostate carcinogenesis and therapies: involvement of EGF-EGFR transduction system

1 reference

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30 September 2017

EPLIN regulates actin dynamics by cross-linking and stabilizing filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548460

30 September 2017

Inhibition of anchorage-independent growth of transformed NIH3T3 cells by epithelial protein lost in neoplasm (EPLIN) requires localization of EPLIN to actin cytoskeleton

1 reference

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HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

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Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

1 reference

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Characterization of the human EPLIN (Epithelial Protein Lost in Neoplasm) gene reveals distinct promoters for the two EPLIN isoforms

1 reference

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30 September 2017

EPLIN, epithelial protein lost in neoplasm

1 reference

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Androgen-repressed phenotype in human prostate cancer

1 reference

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Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

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Fibroblasts are critical determinants in prostatic cancer growth and dissemination

1 reference

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Epithelial protein lost in neoplasm (EPLIN) interacts with α-catenin and actin filaments in endothelial cells and stabilizes vascular capillary network in vitro.

1 reference

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Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts

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EPLIN-α expression in human oesophageal cancer and its impact on cellular aggressiveness and clinical outcome.

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The impact of EPLINα (Epithelial protein lost in neoplasm) on endothelial cells, angiogenesis and tumorigenesis.

1 reference

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Epidermal growth factor receptor (ErbB1) expression in prostate cancer progression: correlation with androgen independence.

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Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials

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Expression patterns of potential therapeutic targets in prostate cancer.

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Expression of epidermal growth factor receptor correlates with disease relapse and progression to androgen-independence in human prostate cancer

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Genetic Polymorphism in EGF Is Associated with Prostate Cancer Aggressiveness and Progression-Free Interval in Androgen Blockade-Treated Patients

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21 January 2018

Reprint of: Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23188829

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP-responsive element-binding protein regulates vascular endothelial growth factor expression: implication in human prostate cancer bone metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23188829

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of bone metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23188829

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.438341

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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