(Q36544889)

14 August 2017

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title

Precision-cut organ slices to investigate target organ injury (English)

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14 August 2017

Alison E M Vickers

1

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14 August 2017

Robyn L Fisher

series ordinal

2

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14 August 2017

language of work or name

English

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publication date

1 December 2005

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Expert Opinion on Drug Metabolism & Toxicology

14 August 2017

published in

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14 August 2017

volume

1

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14 August 2017

issue

4

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14 August 2017

page(s)

687-699

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Timing of new black box warnings and withdrawals for prescription medications

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Drug-induced liver injury: mechanisms and test systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Drug-induced hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Recognizing drug-induced liver injury: current problems, possible solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Heterogeneity of toxicant response: sources of human variability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Long-term culture of functional hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Modeling tissue-specific signaling and organ function in three dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

New insights into functional aspects of liver morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Role of macrophages and inflammatory mediators in chemically induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Adverse hepatic drug reactions: inflammatory episodes as consequence and contributor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Human liver quality is a dominant factor in the outcome of in vitro studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Organ slice viability extended for pathway characterization: an in vitro model to investigate fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Ultrastructural changes in hepatocytes of precision-cut rat liver slices after incubation for 24 and 48 hours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Extracellular diffusion is fast and isotropic in the stratum radiatum of hippocampal CA1 region in rat brain slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

A new technique for preparing precision-cut slices from small intestine and colon for drug biotransformation studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

An in vivo and in vitro comparison of CYP induction in rat liver and intestine using slices and quantitative RT-PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Precision-cut liver slices: characteristics and use for in vitro pharmaco-toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Uptake-toxicity relationships of a series of N-substituted N'-(4-imidazole-ethyl)thiourea in precision-cut rat liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

The applicability of rat and human liver slices to the study of mechanisms of hepatic drug uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Induction of cytochrome P450 2B6 and 3A4 expression by phenobarbital and cyclophosphamide in cultured human liver slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: correlation study with induction in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

In vitro induction of cytochrome P4503A1-mRNA and testosterone hydroxylation in precision-cut liver slices from male and female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

The use of precision-cut liver slices from male Wistar rats as a tool to study age related changes in CYP3A induction and in formation of paracetamol conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Effects of phenytoin on glutathione status and oxidative stress biomarker gene mRNA levels in cultured precision human liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Metabolism of nicotine and induction of CYP1A forms in precision-cut rat liver and lung slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Comparison of in vitro preparations for semi-quantitative prediction of in vivo drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Prediction of whole-body metabolic clearance of drugs through the combined use of slices from rat liver, lung, kidney, small intestine and colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Phase I and phase II metabolic activities are retained in liver slices from mouse, rat, dog, monkey and human after cryopreservation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Metabolic viability and pharmaco-toxicological reactivity of cryopreserved human precision-cut renal cortical slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

In vitro induction of cytochrome P450 2B1- and 3A1-mRNA and enzyme immunostaining in cryopreserved precision-cut rat liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Biotransformation activity in vitrified human liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Cryopreservation of precision-cut tissue slices for application in drug metabolism research

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Microarray analysis in human hepatocytes suggests a mechanism for hepatotoxicity induced by trovafloxacin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Assessment of hepatocytes and liver slices as in vitro test systems to predict in vivo gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Kidney slices of human and rat to characterize cisplatin-induced injury on cellular pathways and morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Identification of platform-independent gene expression markers of cisplatin nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Extended rat liver slice survival and stability monitored using clinical biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

In vitro detection of differential and cell-specific hepatobiliary toxicity induced by geldanamycin and 17-allylaminogeldanamycin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

In vitro detection of differential and cell-specific hepatobiliary toxicity induced by geldanamycin and 17-allylaminogeldanamycin using dog liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Characteristics of glutamine metabolism in human precision-cut kidney slices: a 13C-NMR study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Evaluation of cultured, precision-cut rat liver slices as a model to study drug-induced liver apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

The early allergic response in small airways of human precision-cut lung slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Biphasic culture of rat lung slices for pharmacotoxicological evaluation of complex atmospheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Tissue repair: an important determinant of final outcome of toxicant-induced injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Role of Hepatic Stellate Cells in the Early Phase of Liver Regeneration in Rat: Formation of Tight Adhesion to Parenchymal Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

PPAR Gamma and Hepatic Stellate Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.687

21 January 2018

Identifiers

DOI

10.1517/17425255.1.4.687

1 reference

14 August 2017

1 reference