(Q40458549)

20 September 2017

Microarray analysis in human hepatocytes suggests a mechanism for hepatotoxicity induced by trovafloxacin. (English)

1 reference

20 September 2017

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Michael J Liguori

1

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20 September 2017

Mark G Anderson

2

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20 September 2017

Stanley Bukofzer

3

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20 September 2017

James McKim

4

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20 September 2017

Jeffrey F Pregenzer

5

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20 September 2017

Jacques Retief

6

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20 September 2017

Brian B Spear

7

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20 September 2017

Jeffrey F Waring

8

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20 September 2017

language of work or name

English

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publication date

1 January 2005

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20 September 2017

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20 September 2017

41

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20 September 2017

1

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20 September 2017

177-186

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Applications of microarrays with toxicologically relevant genes (tox genes) for the evaluation of chemical toxicants in Sprague Dawley rats in vivo and human hepatocytes in vitro

20 September 2017

1 reference

Two Mitofusin Proteins, Mammalian Homologues of FZO, with Distinct Functions Are Both Required for Mitochondrial Fusion

21 January 2018

1 reference

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

21 January 2018

1 reference

7 January 2021

Idiosyncratic drug reactions: the reactive metabolite syndromes

1 reference

7 January 2021

Advances in molecular toxicology-towards understanding idiosyncratic drug toxicity

1 reference

7 January 2021

Role of mitochondrial permeability transition in diclofenac-induced hepatocyte injury in rats

1 reference

7 January 2021

Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

1 reference

7 January 2021

Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon

1 reference

7 January 2021

Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats

1 reference

7 January 2021

A review of the common properties of drugs with idiosyncratic hepatotoxicity and the "multiple determinant hypothesis" for the manifestation of idiosyncratic drug toxicity.

1 reference

7 January 2021

Identifying toxic mechanisms using DNA microarrays: evidence that an experimental inhibitor of cell adhesion molecule expression signals through the aryl hydrocarbon nuclear receptor

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7 January 2021

Development of a DNA Microarray for Toxicology Based on Hepatotoxin-Regulated Sequences.

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7 January 2021

Comparative tolerability of the newer fluoroquinolone antibacterials

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7 January 2021

The safety profile of the fluoroquinolones.

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7 January 2021

History of quinolones and their side effects

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7 January 2021

Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes

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7 January 2021

Increased toxicity of cocaine on human hepatocytes induced by ethanol: role of GSH.

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7 January 2021

Isolated human hepatocytes in culture display markedly different gene expression patterns depending on attachment status

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7 January 2021

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

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7 January 2021

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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7 January 2021

Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis

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7 January 2021

Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles

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7 January 2021

NetAffx: Affymetrix probesets and annotations

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7 January 2021

Multiple-dose pharmacokinetics and safety of trovafloxacin in healthy volunteers

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7 January 2021

The use of cultured hepatocytes to investigate the metabolism of drugs and mechanisms of drug hepatotoxicity.

1 reference

7 January 2021

Structural basis for selectivity and toxicity of ribosomal antibiotics

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7 January 2021

Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

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7 January 2021

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

1 reference

7 January 2021

The quinolone family: from antibacterial to anticancer agents

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7 January 2021

Type II topoisomerases as targets for quinolone antibacterials: turning Dr. Jekyll into Mr. Hyde

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7 January 2021

DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates

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7 January 2021

Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.20514

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20 September 2017

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