(Q36544981)

14 August 2017

1 reference

title

Pharmacogenetic differences and drug-drug interactions in immunosuppressive therapy (English)

1 reference

14 August 2017

0 references

Jill S Warrington

1

1 reference

14 August 2017

Leslie M Shaw

series ordinal

2

1 reference

14 August 2017

language of work or name

English

0 references

publication date

1 October 2005

1 reference

Expert Opinion on Drug Metabolism & Toxicology

14 August 2017

published in

1 reference

14 August 2017

volume

1

1 reference

14 August 2017

issue

3

1 reference

14 August 2017

page(s)

487-503

1 reference

New concepts in organ transplantation.

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Renal transplantation in adolescents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Pharmacokinetic, pharmacodynamic, and outcome investigations as the basis for mycophenolic acid therapeutic drug monitoring in renal and heart transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Pharmacogenetics in solid organ transplantation: present knowledge and future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

From pharmacokinetics to pharmacogenomics: a new approach to tailor immunosuppressive therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Review of select transplant subpopulations at high risk of failure from standard immunosuppressive therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Population pharmacokinetics of cyclosporine in cardiopulmonary transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Mycophenolic acid pharmacokinetics in pediatric liver transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Mycophenolic acid levels in pediatric heart transplant recipients receiving mycophenolate mofetil

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Age-dependency of mycophenolate mofetil dosing in combination with tacrolimus after pediatric renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Effect of age, ethnicity, and glucocorticoid use on tacrolimus pharmacokinetics in pediatric renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Immunosuppressive drug monitoring of sirolimus and cyclosporine in pediatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Everolimus in pediatric de nova renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Utility of azathioprine metabolite measurements in post-transplant recurrent autoimmune and immune-mediated hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Pharmacokinetics of mycophenolic acid in renal insufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Population pharmacokinetics of tacrolimus in adult kidney transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Influence of hepatic impairment on everolimus pharmacokinetics: implications for dose adjustment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Effect of grapefruit juice on Sandimmun Neoral absorption among stable renal allograft recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Food-drug interaction: grapefruit juice augments drug bioavailability--mechanism, extent and relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Effect of low- and high-fat meals on tacrolimus absorption following 5 mg single oral doses to healthy human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Inhibitory effects of pomelo on the metabolism of tacrolimus and the activities of CYP3A4 and P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Exposure-response relationships and drug interactions of sirolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Effect of food on everolimus absorption: quantification in healthy subjects and a confirmatory screening in patients with renal transplants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Clinical development of an everolimus pediatric formulation: relative bioavailability, food effect, and steady-state pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

In vivo higher glucuronidation of mycophenolic acid in male than in female recipients of a cadaveric kidney allograft and under immunosuppressive therapy with mycophenolate mofetil

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Equivalent pharmacokinetics of mycophenolate mofetil in African-American and Caucasian male and female stable renal allograft recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Demographic considerations in tacrolimus pharmacokinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Population pharmacokinetics of everolimus in de novo renal transplant patients: impact of ethnicity and comedications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Thiopurine S-methyltransferase polymorphisms: efficient screening method for patients considering taking thiopurine drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Gender-dependent racial difference in disposition of cyclosporine among healthy African American and white volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Cyclosporine pharmacokinetics and pharmacodynamics in African American and white subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Racial differences in renal transplantation after immunosuppression with tacrolimus versus cyclosporine. FK506 Kidney Transplant Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Immunosuppression: towards a logical approach in liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Effect of immunosuppressive agents on long-term survival of renal transplant recipients: focus on the cardiovascular risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Cytochrome P450 3A polymorphisms and immunosuppressive drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Identification of uridine diphosphate glucuronosyltransferases involved in the metabolism and clearance of mycophenolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Clinical pharmacokinetics of everolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Azathioprine: current status and future considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Steroid withdrawal in pediatric and adult renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The value of C2 monitoring in stable renal allograft recipients on maintenance immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

New developments in the immunosuppressive drug monitoring of cyclosporine, tacrolimus, and azathioprine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Variable oral absorption of cyclosporine. A biopharmaceutical risk factor for chronic renal allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Detection of known and new mutations in the thiopurine S-methyltransferase gene by single-strand conformation polymorphism analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

CYP3A5 polymorphism and the ethnic differences in cyclosporine pharmacokinetics in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Cytochromes P450, drugs, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Increased transcriptional activity of the CYP3A4*1B promoter variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Genotype???phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Tacrolimus pharmacogenetics: the CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Glucuronidation and the UDP-glucuronosyltransferases in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Clinical pharmacokinetics of mycophenolate mofetil

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Identification of glucoside and carboxyl-linked glucuronide conjugates of mycophenolic acid in plasma of transplant recipients treated with mycophenolate mofetil

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Induction of cytokine release by the acyl glucuronide of mycophenolic acid: a link to side effects?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Transport proteins and intestinal metabolism: P-glycoprotein and cytochrome P4503A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Functional evaluation of ABCB1 (P-glycoprotein) polymorphisms: high-speed screening and structure-activity relationship analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

MDR-1 C3435T polymorphism influences cyclosporine a dose requirement in liver-transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Increased tacrolimus trough levels in association with severe diarrhea, a case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Role of transporters in the tissue-selective distribution and elimination of drugs: transporters in the liver, small intestine, brain and kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Efficient inhibition of multidrug-resistant human tumors with a recombinant bispecific anti-P-glycoprotein x anti-CD3 diabody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Effect of calcineurin inhibitor therapy on P-gp expression and function in lymphocytes of renal transplant patients: a preliminary evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Functional Distinctions between IMP Dehydrogenase Genes in Providing Mycophenolate Resistance and Guanine Prototrophy to Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Pre-transplant inosine monophosphate dehydrogenase activity is associated with clinical outcome after renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Genetic conservation of the immunophilin-binding domains of human calcineurin A1 and A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Calcineurin: not just a simple protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Effect of cyclosporin pharmacokinetics on renal allograft outcome in African-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The pharmacokinetics of mycophenolate mofetil in Thai kidney transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The effect of sevelamer on the pharmacokinetics of cyclosporin A and mycophenolate mofetil after renal transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Tacrolimus and lopinavir/ritonavir interaction in liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Concomitant human immunodeficiency virus protease inhibitor therapy markedly reduces tacrolimus metabolism and increases blood levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Sirolimus and erythromycin interaction: two cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Glucocorticoids interfere with mycophenolate mofetil bioavailability in kidney transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Alterations of cyclosporin A metabolism induced by mycophenolate mofetil

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Prospects for personalized immunosuppression: pharmacologic tools--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Sirolimus steady-state trough concentrations are not affected by bolus methylprednisolone therapy in renal allograft recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

Modulation of mdr1a and CYP3A gene expression in the intestine and liver as possible cause of changes in the cyclosporin A disposition kinetics by dexamethasone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

The Effect of CYP3A5 and MDR1 Polymorphic Expression on Cyclosporine Oral Disposition in Renal Transplant Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.487

21 January 2018

Identifiers

DOI

10.1517/17425255.1.3.487

1 reference

14 August 2017

1 reference