(Q36553327)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Modulation of methuselah expression targeted to Drosophila insulin-producing cells extends life and enhances oxidative stress resistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

5

1 reference

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16 February 2020

8

Steven N Austad

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Luis E D Gimenez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Parakashtha Ghildyal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Kathleen E Fischer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Hongxiang Hu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Benjamin A Eaton

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Yimin Wu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Ravi Ranjan

9

1 reference

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16 February 2020

publication date

6 December 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

121-129

1 reference

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describes a project that uses

16 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3552032/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Interplay between FOXO, TOR, and Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Blocking O-Linked GlcNAc Cycling in Drosophila Insulin-producing Cells Perturbs Glucose-Insulin Homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

SH2B regulation of growth, metabolism, and longevity in both insects and mammals

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Molecular evolution and functional characterization of Drosophila insulin-like peptides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

The Drosophila G protein-coupled receptor, Methuselah, exhibits a promiscuous response to peptides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

The structure and function of G-protein-coupled receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Insulin and JNK: optimizing metabolic homeostasis and lifespan

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Insulin/IGF-like signalling, the central nervous system and aging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Drosophila germ-line modulation of insulin signaling and lifespan

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

FoxO transcription factors in the maintenance of cellular homeostasis during aging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Age-dependent stability of sensorimotor functions in the life-extended Drosophila mutant methuselah

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Regulation of receptor trafficking by GRKs and arrestins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Drosophila lacking microRNA miR-278 are defective in energy homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

The endocrine regulation of aging by insulin-like signals

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Extended longevity in mice lacking the insulin receptor in adipose tissue

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Adaptive evolution of a candidate gene for aging in Drosophila

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Extended life-span and stress resistance in the Drosophila mutant methuselah

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Regulation of lifespan by sensory perception in Caenorhabditis elegans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Disappearance of organochlorine residues from abdominal and egg fats of chickens, Ontario, Canada, 1969-1982.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552032

Methuselah life history in a variety of conditions, implications for the use of mutants in longevity research

28 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12027

The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12027

Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12027

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12027

Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12027

Antioxidant status and stress resistance in long- and short-lived lines of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12027

Presynaptic regulation of neurotransmission in Drosophila by the g protein-coupled receptor methuselah

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12027

Dynamics of the male germline stem cell population during aging of Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12027

21 January 2018

Identifiers

DOI

10.1111/ACEL.12027

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23121290%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

23121290

1 reference