(Q36563545)

14 August 2017

1 reference

title

Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation (English)

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14 August 2017

3

Fiona Powrie

1 reference

14 August 2017

Ana Izcue

1

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14 August 2017

Janine L Coombes

series ordinal

2

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14 August 2017

publication date

1 August 2006

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14 August 2017

published in

Immunological Reviews

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14 August 2017

volume

212

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14 August 2017

page(s)

256-271

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Transcription factors in autoimmunity

14 August 2017

cites work

1 reference

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CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

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21 January 2018

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Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

21 January 2018

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Acquisition of anergic and suppressive activities in transforming growth factor-beta-costimulated CD4+CD25- T cells

21 January 2018

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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

21 January 2018

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

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Regulatory T cells and mechanisms of immune system control

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Regulatory T cells: friend or foe in immunity to infection?

21 January 2018

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Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora

21 January 2018

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Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis

21 January 2018

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IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

21 January 2018

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Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

21 January 2018

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Cutting edge: CD4+CD25+ regulatory T cells impaired for intestinal homing can prevent colitis.

21 January 2018

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Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells

21 January 2018

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21 January 2018

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Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering

21 January 2018

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A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

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TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

21 January 2018

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CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

21 January 2018

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21 January 2018

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Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

21 January 2018

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T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

21 January 2018

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21 January 2018

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TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

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CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes

21 January 2018

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TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

21 January 2018

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TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes

21 January 2018

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CD28 disruption exacerbates inflammation in Tgf-beta1-/- mice: in vivo suppression by CD4+CD25+ regulatory T cells independent of autocrine TGF-beta1.

21 January 2018

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Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

1 reference

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T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

21 January 2018

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Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

21 January 2018

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21 January 2018

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21 January 2018

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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

21 January 2018

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21 January 2018

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CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

21 January 2018

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Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.

21 January 2018

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A molecular perspective of CTLA-4 function

21 January 2018

1 reference

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

21 January 2018

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CTLA-4-Ig regulates tryptophan catabolism in vivo.

21 January 2018

1 reference

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Modulation of tryptophan catabolism by regulatory T cells.

21 January 2018

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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

21 January 2018

1 reference

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Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.

21 January 2018

1 reference

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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Innate immune recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance

21 January 2018

1 reference

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Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

21 January 2018

1 reference

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Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

21 January 2018

1 reference

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

21 January 2018

1 reference

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Homing and cellular traffic in lymph nodes

21 January 2018

1 reference

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Lymphocyte homing to the gut: attraction, adhesion, and commitment

21 January 2018

1 reference

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Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ + gut intraepithelial lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Reciprocal and dynamic control of CD8 T cell homing by dendritic cells from skin- and gut-associated lymphoid tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

21 January 2018

1 reference

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Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant.

21 January 2018

1 reference

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Retinoic acid imprints gut-homing specificity on T cells

21 January 2018

1 reference

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Mechanisms of binding of cutaneous lymphocyte-associated antigen-positive and alphaebeta7-positive lymphocytes to oral and skin keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an E-cadherin-independent interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

21 January 2018

1 reference

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Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Essential role for CD103 in the T cell-mediated regulation of experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

The role of beta7 integrins in CD8 T cell trafficking during an antiviral immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00423.X

Cutting Edge: TGF- Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T Cells

21 January 2018

1 reference

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10.1111/J.0105-2896.2006.00423.X

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference