(Q36564840)

15 August 2017

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title

Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms (English)

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15 August 2017

3

K Fuxe

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15 August 2017

G Mudo

1

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PubMed ID

16906354

15 August 2017

N Belluardo

series ordinal

2

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15 August 2017

17 August 2006

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Journal of Neural Transmission

15 August 2017

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15 August 2017

114

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15 August 2017

1

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15 August 2017

135-147

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https://scigraph.springernature.com/pub.10.1007/s00702-006-0561-z

15 August 2017

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Loss of nicotinic acetylcholine receptor subunits alpha4 and alpha7 in the cerebral cortex of Parkinson patients

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Drug dependence as a disorder of neural plasticity: focus on dopamine and glutamate

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Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson's disease.

21 January 2018

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Central nicotinic receptors, neurotrophic factors and neuroprotection

21 January 2018

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12 December 2020

Nicotine inhibits amyloid formation by the beta-peptide.

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12 December 2020

Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture

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12 December 2020

Comparative localization of fibroblast growth factor receptor-1, -2, and -3 mRNAs in the rat brain: in situ hybridization analysis

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12 December 2020

Neuronal acetylcholine receptors that bind alpha-bungarotoxin mediate neurite retraction in a calcium-dependent manner

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12 December 2020

Evidence that tobacco smoking increases the density of (-)-[3H]nicotine binding sites in human brain.

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12 December 2020

Heightened synaptic plasticity of hippocampal CA1 neurons during a cholinergically induced rhythmic state

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12 December 2020

The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21).

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12 December 2020

Brain nicotinic receptors: structure and regulation, role in learning and reinforcement

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12 December 2020

Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain

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12 December 2020

Cellular expression of alpha7 nicotinic acetylcholine receptor protein in the temporal cortex in Alzheimer's and Parkinson's disease--a stereological approach.

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12 December 2020

Effects of single injections of nicotine on the ascending dopamine pathways in the rat: Evidence for increases of dopamine turnover in the mesostriatal and mesolimbic dopamine neurons

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12 December 2020

Neuronal nicotinic receptors: from structure to pathology

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12 December 2020

Pharmacologic treatment of Alzheimer's disease: an update

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12 December 2020

Chronic treatment of old rats with donepezil or galantamine: effects on memory, hippocampal plasticity and nicotinic receptors.

1 reference

12 December 2020

Nicotinic receptors in the development and modulation of CNS synapses.

1 reference

12 December 2020

Long-term potentiation of excitatory inputs to brain reward areas by nicotine.

1 reference

12 December 2020

Hippocampal alpha 7 and alpha 4 beta 2 nicotinic receptors and working memory

1 reference

12 December 2020

The choice of antipsychotic drugs for schizophrenia

1 reference

12 December 2020

Transcription factor gene expression profiling after acute intermittent nicotine treatment in the rat cerebral cortex.

1 reference

12 December 2020

Nicotine protects against the dexamethasone potentiation of kainic acid-induced neurotoxicity in cultured hippocampal neurons.

1 reference

12 December 2020

Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice

1 reference

12 December 2020

Molecular basis of long-term plasticity underlying addiction

1 reference

12 December 2020

Nicotine prevents experimental parkinsonism in rodents and induces striatal increase of neurotrophic factors

1 reference

12 December 2020

Nicotinic regulation of CREB activation in hippocampal neurons by glutamatergic and nonglutamatergic pathways

1 reference

12 December 2020

The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism

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12 December 2020

Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity

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12 December 2020

Nicotinic acetylcholine involvement in cognitive function in animals

1 reference

12 December 2020

Relationship between the increased cell surface alpha7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists

1 reference

12 December 2020

Distribution of alpha 2, alpha 3, alpha 4, and beta 2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat.

1 reference

12 December 2020

Role of alpha7 nicotinic receptors in nicotine dependence and implications for psychiatric illness

1 reference

12 December 2020

Protective effects of basic fibroblast growth factor against hippocampal neuronal damage following cerebral ischemia in the gerbil.

1 reference

12 December 2020

Nicotinic receptors differentially regulate N-methyl-D-aspartate damage in acute hippocampal slices

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12 December 2020

The distribution of mRNA encoded by a new member of the neuronal nicotinic acetylcholine receptor gene family (alpha 5) in the rat central nervous system.

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12 December 2020

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12 December 2020

Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo

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12 December 2020

Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors

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12 December 2020

Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity.

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12 December 2020

Nerve growth factor increases nicotinic ACh receptor gene expression and current density in wild-type and protein kinase A-deficient PC12 cells

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12 December 2020

Computer-assisted mapping of basic fibroblast growth factor immunoreactive nerve cell populations in the rat brain.

1 reference

12 December 2020

Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain.

1 reference

12 December 2020

Nicotinic receptors and schizophrenia

1 reference

12 December 2020

Preventing cancer by controlling youth tobacco use.

1 reference

12 December 2020

Nicotinic receptors and cognition in Parkinson's Disease: the importance of neuronal synchrony

1 reference

12 December 2020

Chronic continuous infusion of (-)nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not of the 6-hydroxydopamine-lesioned rat

1 reference

12 December 2020

Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors.

1 reference

12 December 2020

(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization.

1 reference

12 December 2020

Neuroendocrine actions of nicotine and of exposure to cigarette smoke: medical implications

1 reference

12 December 2020

Voltage-gated channels block nicotinic regulation of CREB phosphorylation and gene expression in neurons

1 reference

12 December 2020

The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys

1 reference

12 December 2020

Desensitized nicotinic receptors in brain

1 reference

12 December 2020

Smoking and Parkinson's and Alzheimer's disease: review of the epidemiological studies

1 reference

12 December 2020

Smoking, nicotine and Parkinson's disease

1 reference

12 December 2020

Activation of alpha7 nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons.

1 reference

12 December 2020

Hippocampal synaptic transmission enhanced by low concentrations of nicotine.

1 reference

12 December 2020

Effects of nicotine on hippocampal and cingulate activity during smooth pursuit eye movement in schizophrenia

1 reference

12 December 2020

The role of neuronal nicotinic acetylcholine receptors in acute and chronic neurodegeneration.

1 reference

12 December 2020

Effects of nicotinic stimulation on cognitive performance

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12 December 2020

Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications.

1 reference

12 December 2020

Nicotine-induced protection against glutamate cytotoxicity. Nicotinic cholinergic receptor-mediated inhibition of nitric oxide formation.

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12 December 2020

Chronic nicotine treatment counteracts the disappearance of tyrosine-hydroxylase-immunoreactive nerve cell bodies, dendrites and terminals in the mesostriatal dopamine system of the male rat after partial hemitransection

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12 December 2020

Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies.

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12 December 2020

Chronic nicotine treatment partly protects against the 1-methyl-4-phenyl-2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse.

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12 December 2020

Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers

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12 December 2020

In vivo nicotine treatment regulates mesocorticolimbic CREB and ERK signaling in C57Bl/6J mice

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12 December 2020

Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease.

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12 December 2020

Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex.

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12 December 2020

Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2

1 reference

12 December 2020

Effects of chronic nerve growth factor treatment on hippocampal [3H]cytisine/nicotinic binding sites and presynaptic nicotinic receptor function following fimbrial transections

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12 December 2020

Common molecular and cellular substrates of addiction and memory

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12 December 2020

Stimulation of nigrostriatal dopamine neurones by nicotine.

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12 December 2020

Blockade of basic fibroblast growth factor retards recovery from motor cortex injury in rats.

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12 December 2020

Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture

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12 December 2020

Indicators of neuroprotection with galantamine

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12 December 2020

Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia

1 reference

12 December 2020

Regulation of alpha4beta2 nicotinic receptor desensitization by calcium and protein kinase C.

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12 December 2020

Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders

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12 December 2020

The role of neuronal growth factors in neurodegenerative disorders of the human brain

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12 December 2020

Mitogenic effect of basic fibroblast growth factor on embryonic ventral mesencephalic dopaminergic neurone precursors.

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12 December 2020

Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity

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12 December 2020

Nicotine-induced sensitization to ambulatory stimulant effect produced by daily administration into the ventral tegmental area and the nucleus accumbens in rats

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12 December 2020

Protective effect of GTS-21, a novel nicotinic receptor agonist, on delayed neuronal death induced by ischemia in gerbils.

1 reference

12 December 2020

Chronic nicotine treatment increases dopamine levels and reduces dopamine utilization in substantia nigra and in surviving forebrain dopamine nerve terminal systems after a partial di-mesencephalic hemitransection

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12 December 2020

Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells

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12 December 2020

The involvement of spinal Ca(2+)/calmodulin-protein kinase II in nicotine-induced antinociception in mice

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12 December 2020

Stimulation of non-alpha7 nicotinic receptors partially protects dopaminergic neurons from 1-methyl-4-phenylpyridinium-induced toxicity in culture

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12 December 2020

Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism

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12 December 2020

Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease

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12 December 2020

Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance

1 reference

12 December 2020

Alteration of hippocampal cell proliferation in mice lacking the beta 2 subunit of the neuronal nicotinic acetylcholine receptor

1 reference

12 December 2020

Cellular and synaptic mechanisms of nicotine addiction

1 reference

12 December 2020

The effects of nicotine on Parkinson's disease

1 reference

12 December 2020

The nicotinic acetylcholine receptor agonist ABT-594 increases FGF-2 expression in various rat brain regions

1 reference

12 December 2020

Tropisetron improves deficits in auditory P50 suppression in schizophrenia

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12 December 2020

Trophic factors and neuronal survival

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12 December 2020

Stimulatory role of dopamine on fibroblast growth factor-2 expression in rat striatum.

1 reference

12 December 2020

Nicotine attenuates arachidonic acid-induced overexpression of nitric oxide synthase in cultured spinal cord neurons

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12 December 2020

The paradox of nicotinic acetylcholine receptor upregulation by nicotine

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12 December 2020

Protective effects of chronic nicotine treatment on lesioned nigrostriatal dopamine neurons in the male rat

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12 December 2020

Cognitive mechanisms of nicotine on visual attention

1 reference

12 December 2020

Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain.

1 reference

12 December 2020

(-)Nicotine inhibits the activations of phospholipases A2 and D by amyloid beta peptide.

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12 December 2020

Desensitization of nicotinic ACh receptors: shaping cholinergic signaling

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12 December 2020

Involvement of alpha7 nicotinic acetylcholine receptors in activation of tyrosine hydroxylase and dopamine beta-hydroxylase gene expression in PC12 cells

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12 December 2020

Drugs of abuse and immediate-early genes in the forebrain

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12 December 2020

NMDA potentiates NGF-induced sprouting of septal cholinergic fibres.

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12 December 2020

Nicotine enhances contextual fear conditioning in C57BL/6J mice at 1 and 7 days post-training

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12 December 2020

Allosteric sensitization of nicotinic receptors by galantamine, a new treatment strategy for Alzheimer's disease

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12 December 2020

Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells

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12 December 2020

Acute intermittent nicotine treatment produces regional increases of basic fibroblast growth factor messenger RNA and protein in the tel- and diencephalon of the rat.

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12 December 2020

Effects of chronic nicotine treatment on the expression of phospholipase C isozymes and the alpha subunit of Gq/11 protein in the rat brain.

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12 December 2020

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

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12 December 2020

The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences

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12 December 2020

Protective actions of human recombinant basic fibroblast growth factor on MPTP-lesioned nigrostriatal dopamine neurons after intraventricular infusion.

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12 December 2020

Nicotinic receptor abnormalities in Alzheimer's disease

1 reference

12 December 2020

Effects of ABT-418, a novel cholinergic channel ligand, on place learning in septal-lesioned rats.

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12 December 2020

Diversity of neuronal nicotinic acetylcholine receptors: lessons from behavior and implications for CNS therapeutics

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12 December 2020

Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21.

1 reference

12 December 2020

Using animal models to test a neurodevelopmental hypothesis of schizophrenia

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12 December 2020

Protective effects of nicotine against glutamate-induced neurotoxicity in PC12 cells

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12 December 2020

alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity

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12 December 2020

Alzheimer's disease and Abeta toxicity: from top to bottom

1 reference

12 December 2020

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium.

1 reference

12 December 2020

Why does the rapid delivery of drugs to the brain promote addiction?

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12 December 2020

The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory.

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12 December 2020

Characterization of the neuroprotective and toxic effects of alpha7 nicotinic receptor activation in PC12 cells.

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12 December 2020

NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis

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12 December 2020

Chronic nicotine reverses working memory deficits caused by lesions of the fimbria or medial basalocortical projection.

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12 December 2020

Nicotinic receptors in the rat prefrontal cortex: increase in glutamate release and facilitation of mediodorsal thalamo-cortical transmission.

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12 December 2020

The molecular biology of memory storage: a dialogue between genes and synapses

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12 December 2020

Allosteric nicotinic receptors, human pathologies.

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12 December 2020

Nicotine and epibatidine triggered prolonged rise in calcium and TH gene transcription in PC12 cells

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12 December 2020

AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats.

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12 December 2020

Nicotine self-administration impairs hippocampal plasticity.

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12 December 2020

Mu-opioid receptor and CREB activation are required for nicotine reward

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12 December 2020

Increased tyrosine phosphorylation and novel cis-acting element mediate activation of the fibroblast growth factor-2 (FGF-2) gene by nicotinic acetylcholine receptor. New mechanism for trans-synaptic regulation of cellular development and plasticity

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12 December 2020

Survival of Adult Basal Forebrain Cholinergic Neurons After Loss of Target Neurons

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12 December 2020

Nicotine upregulates its own receptors through enhanced intracellular maturation

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12 December 2020

The prefrontal cortex and the integration of sensory, limbic and autonomic information

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12 December 2020

Development of nicotinic drug therapy for cognitive disorders.

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12 December 2020

Nicotine and its interaction with beta-amyloid protein: a short review

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12 December 2020

Tyrosine kinases are required for catecholamine secretion and mitogen-activated protein kinase activation in bovine adrenal chromaffin cells.

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12 December 2020

Facilitation of learning and state dependency with nicotine

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12 December 2020

Galantamine for treatment-resistant schizophrenia

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12 December 2020

Synaptic plasticity and nicotine addiction

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12 December 2020

Effects of protracted nicotine exposure and withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat brain

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12 December 2020

Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo

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12 December 2020

The alpha7 nicotinic acetylcholine receptor in neuronal plasticity

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12 December 2020

Molecular studies of the neuronal nicotinic acetylcholine receptor family

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12 December 2020

Inhibition and disinhibition of pyramidal neurons by activation of nicotinic receptors on hippocampal interneurons.

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12 December 2020

Effects of local and repeated systemic administration of (-)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex

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12 December 2020

Nicotine modulates the expression of a diverse set of genes in the neuronal SH-SY5Y cell line

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12 December 2020

Chronic nicotine treatment counteracts nigral cell loss induced by a partial mesodiencephalic hemitransection: an analysis of the total number and mean volume of neurons and glia in substantia nigra of the male rat

1 reference

12 December 2020

The nicotinic acetylcholine receptor agonist (+/-)-epibatidine increases FGF-2 mRNA and protein levels in the rat brain

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12 December 2020

Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity

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12 December 2020

Acute and chronic nicotine exposure reverse age-related declines in the induction of long-term potentiation in the rat hippocampus.

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12 December 2020

Overview of nicotinic receptors and their roles in the central nervous system

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12 December 2020

4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A): a novel cognitive enhancer with selectivity for neuronal nicotinic acetylcholine receptors

1 reference

12 December 2020

A functional role for nicotine in Bcl2 phosphorylation and suppression of apoptosis

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12 December 2020

Therapeutic implications of a selective alpha7 nicotinic receptor abnormality in schizophrenia.

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12 December 2020

Pharmacological characterization of nicotinic receptor-mediated acetylcholine release in rat brain--an in vivo microdialysis study.

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12 December 2020

Nicotinic treatment of Alzheimer's disease

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12 December 2020

Increases in dopamine utilization in certain limbic dopamine terminal populations after a short period of intermittent exposure of male rats to cigarette smoke

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12 December 2020

Modulatory effect of ginseng total saponin on dopamine release and tyrosine hydroxylase gene expression induced by nicotine in the rat

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12 December 2020

Properties and plasticity of excitatory synapses on dopaminergic and GABAergic cells in the ventral tegmental area.

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12 December 2020

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

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12 December 2020

10.1007/S00702-006-0561-Z

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

16906354