(Q36572610)

English

The rise of PAMPA.

scientific article published on August 2005

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scholarly article

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Europe PubMed Central

15 August 2017

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Europe PubMed Central

The rise of PAMPA. (English)

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Europe PubMed Central

15 August 2017

author name string

Alex Avdeef

1

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Europe PubMed Central

15 August 2017

language of work or name

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publication date

1 August 2005

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Europe PubMed Central

15 August 2017

Expert Opinion on Drug Metabolism & Toxicology

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Europe PubMed Central

15 August 2017

1

1 reference

Europe PubMed Central

15 August 2017

2

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Europe PubMed Central

15 August 2017

325-342

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Europe PubMed Central

15 August 2017

Absorption potential: estimating the fraction absorbed for orally administered compounds

1 reference

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A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

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Quantitative biopharmaceutics classification system: the central role of dose/solubility ratio.

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Guidance in the setting of drug particle size specifications to minimize variability in absorption

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Passive diffusion of weak organic electrolytes across Caco-2 cell monolayers: uncoupling the contributions of hydrodynamic, transcellular, and paracellular barriers.

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21 January 2018

Drug absorption in vitro model: filter-immobilized artificial membranes. 2. Studies of the permeability properties of lactones in Piper methysticum Forst

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21 January 2018

Optimized conditions of bio-mimetic artificial membrane permeation assay

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21 January 2018

High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes

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21 January 2018

Molecular properties that influence the oral bioavailability of drug candidates

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21 January 2018

High throughput artificial membrane permeability assay for blood-brain barrier.

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21 January 2018

Prediction of human intestinal permeability using artificial membrane permeability

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21 January 2018

PAMPA--a drug absorption in vitro model. 5. Unstirred water layer in iso-pH mapping assays and pKa(flux)--optimized design (pOD-PAMPA).

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21 January 2018

In vitro permeability of poorly aqueous soluble compounds using different solubilizers in the PAMPA assay with liquid chromatography/mass spectrometry detection

1 reference

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21 January 2018

PAMPA--a drug absorption in vitro model 8. Apparent filter porosity and the unstirred water layer

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21 January 2018

Permeability through DOPC/dodecane membranes: measurement and LFER modelling.

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21 January 2018

PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.

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21 January 2018

Acid-base cosolvent method for determining aqueous permeability of amiodarone, itraconazole, tamoxifen, terfenadine and other very insoluble molecules

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Comparison of in vitro models for the prediction of compound absorption across the human intestinal mucosa

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Ionization, lipophilicity, and molecular modeling to investigate permeability and other biological properties of amlodipine

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Probing the mechanism of drug/lipid membrane interactions using Biacore

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Contribution of the paracellular route to the pH-dependent epithelial permeability to cationic drugs

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Exploring the role of different drug transport routes in permeability screening.

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Physicochemical profiling (solubility, permeability and charge state).

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High throughput physicochemical profiling for drug discovery

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Multivariate pharmaceutical profiling for drug discovery

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Improvement of "hit-to-lead" optimization by integration of in vitro HTS experimental models for early determination of pharmacokinetic properties

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Pharmaceutical profiling in drug discovery.

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Profiling drug-like properties in discovery research

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21 January 2018

In vitro trans-monolayer permeability calculations: often forgotten assumptions

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21 January 2018

Physicochemical profiling in drug research: a brief survey of the state-of-the-art of experimental techniques

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21 January 2018

Diffusion of Weak Acids across Lipid Bilayer Membranes: Effects of Chemical Reactions in the Unstirred Layers

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21 January 2018

Weak acid transport across bilayer lipid membrane in the presence of buffers. Theoretical and experimental pH profiles in the unstirred layers

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21 January 2018

Diffusion of ionizable solutes across planar lipid bilayer membranes: boundary-layer pH gradients and the effect of buffers.

1 reference

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21 January 2018

Human intestinal permeability

1 reference

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21 January 2018

Application of hydrogen bonding calculations in property based drug design.

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Classification analysis of P-glycoprotein substrate specificity

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Identifiers

10.1517/17425255.1.2.325

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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