(Q36576992)

15 August 2017

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title

Drug insight: Bisphosphonates for postmenopausal osteoporosis (English)

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15 August 2017

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Roland D Chapurlat

1

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15 August 2017

Pierre D Delmas

series ordinal

2

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15 August 2017

publication date

1 April 2006

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Nature Clinical Practice Endocrinology and Metabolism

15 August 2017

published in

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15 August 2017

volume

2

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15 August 2017

issue

4

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15 August 2017

page(s)

211-9; quiz following 238

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Bisphosphonates: pharmacology, mechanisms of action and clinical uses

15 August 2017

cites work

1 reference

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21 January 2018

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21 January 2018

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21 January 2018

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Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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Bisphosphonates stimulate formation of osteoblast precursors and mineralized nodules in murine and human bone marrow cultures in vitro and promote early osteoblastogenesis in young and aged mice in vivo

21 January 2018

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Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis

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21 January 2018

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21 January 2018

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21 January 2018

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Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Insufficiently dosed intravenous ibandronate injections are associated with suboptimal antifracture efficacy in postmenopausal osteoporosis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib.

21 January 2018

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Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles

21 January 2018

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Alendronate Prevents Postmenopausal Bone Loss in Women without Osteoporosis: A Double-Blind, Randomized, Controlled Trial

21 January 2018

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Inhibitory effects of bisphosphonates on growth of amoebae of the cellular slime mold Dictyostelium discoideum

21 January 2018

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7 January 2021

Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0121

7 January 2021

Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite

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7 January 2021

Treatment with alendronate prevents fractures in women at highest risk: results from the Fracture Intervention Trial

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0121

7 January 2021

Dose-proportional pharmacokinetics of risedronate on single-dose oral administration to healthy volunteers

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0121

7 January 2021

Long-term treatment of incadronate disodium accumulates microdamage but improves the trabecular bone microarchitecture in dog vertebra

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0121

7 January 2021

Identifiers

DOI

10.1038/NCPENDMET0121

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15 August 2017

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