(Q36577386)

15 August 2017

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title

Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis (English)

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15 August 2017

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1

Ulf Müller-Ladner

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15 August 2017

Thomas Pap

2

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15 August 2017

Renate E Gay

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3

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15 August 2017

Michel Neidhart

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4

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15 August 2017

Steffen Gay

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5

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15 August 2017

1 December 2005

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Nature Clinical Practice Rheumatology

15 August 2017

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15 August 2017

1

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15 August 2017

2

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15 August 2017

102-110

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Early growth response factor-1 mediates prostaglandin E2-dependent transcriptional suppression of cytokine-induced tumor necrosis factor-alpha gene expression in human macrophages and rheumatoid arthritis-affected synovial fibroblasts

15 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity: evidence of a link between an increased myofibroblast-like phenotype and high-inflammation synovitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Evolving concepts of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Targeting IL-15 receptor-bearing cells with an antagonist mutant IL-15/Fc protein prevents disease development and progression in murine collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Elevated CXCL16 expression by synovial macrophages recruits memory T cells into rheumatoid joints.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

The different stages of synovitis: acute vs chronic, early vs late and non-erosive vs erosive

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin alpha5beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Discrepancy between mRNA and protein expression of tumour suppressor maspin in synovial tissue may contribute to synovial hyperplasia in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Activation of synovial fibroblasts in rheumatoid arthritis: lack of Expression of the tumour suppressor PTEN at sites of invasive growth and destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Therapeutic strategies for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Synovial fluid CD146 (MUC18), a marker for synovial membrane angiogenesis in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Adenoviral delivery of soluble VEGF receptor 1 (sFlt-1) abrogates disease activity in murine collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Autocrine/paracrine role of the angiopoietin-1 and -2/Tie2 system in cell proliferation and chemotaxis of cultured fibroblastic synoviocytes in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Plasminogen activation/plasmin in rheumatoid arthritis: matrix degradation and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Reduction of arthritis severity in protease-activated receptor-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Expression and localisation of the new metalloproteinase inhibitor RECK (reversion inducing cysteine-rich protein with Kazal motifs) in inflamed synovial membranes of patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Galectin-3 is induced in rheumatoid arthritis synovial fibroblasts after adhesion to cartilage oligomeric matrix protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Clinical Aspects of Immune Neuroendocrine Mechanisms in Rheumatic Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

The angiogenic pathway ?vascular endothelial growth factor/flk-1(KDR)-receptor? in rheumatoid arthritis and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

Identification of differentially expressed genes in rheumatoid arthritis by a combination of complementary DNA array and RNA arbitrarily primed-polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

The RANK/RANKL/osteoprotegerin system in rheumatoid arthritis: new insights from animal models

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https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Lymphoid neogenesis in rheumatoid synovitis

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https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

CXCL13 neutralization reduces the severity of collagen-induced arthritis

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https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Interleukin-16, produced by synovial fibroblasts, mediates chemoattraction for CD4+ T lymphocytes in rheumatoid arthritis

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https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Fibroblast-like synoviocytes from rheumatoid arthritis patients express functional IL-15 receptor complex: endogenous IL-15 in autocrine fashion enhances cell proliferation and expression of Bcl-x(L) and Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

FLICE-inhibitory protein expression in synovial fibroblasts and at sites of cartilage and bone erosion in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Osteoprotegerin (OPG) acts as an endogenous decoy receptor in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of fibroblast-like synovial cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Differential expression pattern of membrane-type matrix metalloproteinases in rheumatoid arthritis

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https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Adipocytokines in synovial fluid

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https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Resistin, an adipokine with potent proinflammatory properties

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https://api.crossref.org/works/10.1038%2FNCPRHEUM0047

7 January 2021

Identifiers

DOI

10.1038/NCPRHEUM0047

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15 August 2017

1 reference