(Q36577620)

15 August 2017

1 reference

title

How valid are animal models to evaluate treatments for pulmonary hypertension? (English)

1 reference

15 August 2017

3

Martin C Michel

1 reference

15 August 2017

Maria E Campian

1

1 reference

PubMed ID

16932922

15 August 2017

Maxim Hardziyenka

series ordinal

2

1 reference

PubMed ID

16932922

15 August 2017

Hanno L Tan

series ordinal

4

1 reference

15 August 2017

1 September 2006

1 reference

Naunyn-Schmiedeberg's Archives of Pharmacology

15 August 2017

1 reference

15 August 2017

373

1 reference

15 August 2017

6

1 reference

15 August 2017

391-400

1 reference

https://scigraph.springernature.com/pub.10.1007/s00210-006-0087-9

15 August 2017

0 references

cites work

The effect of continued hypoxia on rat pulmonary arterial circulation. An ultrastructural study

1 reference

12 December 2020

Nitric oxide inhalation decreases pulmonary artery remodeling in the injured lungs of rat pups.

1 reference

12 December 2020

A model of embolic chronic pulmonary hypertension in the dog

1 reference

12 December 2020

Short-term hemodynamic effect of a new oral PGI2 analogue, beraprost, in primary and secondary pulmonary hypertension

1 reference

12 December 2020

Antiproliferative effect of sildenafil on human pulmonary artery smooth muscle cells

1 reference

12 December 2020

LU135252, an endothelin(A) receptor antagonist did not prevent pulmonary vascular remodelling or lung fibrosis in a rat model of myocardial infarction

1 reference

12 December 2020

Endothelin mediates pulmonary vascular remodelling in a canine model of chronic embolic pulmonary hypertension

1 reference

12 December 2020

Nonspecific endothelin-receptor antagonist blunts monocrotaline-induced pulmonary hypertension in rats

1 reference

12 December 2020

Hypoxic pulmonary hypertension in man: what minimum daily duration of hypoxaemia is required?

1 reference

12 December 2020

Protection from pulmonary hypertension with an orally active endothelin receptor antagonist in hypoxic rats

1 reference

12 December 2020

Protective effect of beraprost sodium, a stable prostacyclin analogue, in development of monocrotaline-induced pulmonary hypertension

1 reference

12 December 2020

A combination of oral endothelin-A receptor antagonist and oral prostacyclin analogue is superior to each drug alone in ameliorating pulmonary hypertension in rats

1 reference

12 December 2020

Effects of nifedipine-induced pulmonary vasodilatation on cardiac receptors and protein kinase C isoforms in the chronically hypoxic rat.

1 reference

12 December 2020

Sildenafil citrate therapy for pulmonary arterial hypertension

1 reference

12 December 2020

Fetal ductus arteriosus ligation. Pulmonary vascular smooth muscle biochemical and mechanical changes

1 reference

12 December 2020

Sildenafil inhibits altitude-induced hypoxemia and pulmonary hypertension.

1 reference

12 December 2020

Endothelial cell dysfunction correlates differentially with survival in primary and secondary pulmonary hypertension

1 reference

12 December 2020

Time course of pulmonary vascular response to microembolization

1 reference

12 December 2020

Interleukin-1 receptor antagonist treatment reduces pulmonary hypertension generated in rats by monocrotaline

1 reference

12 December 2020

A long-acting prostacyclin agonist with thromboxane inhibitory activity for pulmonary hypertension

1 reference

12 December 2020

Effects of long-term bosentan in children with pulmonary arterial hypertension.

1 reference

12 December 2020

Prevention of pulmonary vascular changes of chronic alveolar hypoxia by inhibition of angiotensin I-converting enzyme in the rat

1 reference

12 December 2020

Prolonged inhaled NO attenuates hypoxic, but not monocrotaline-induced, pulmonary vascular remodeling in rats

1 reference

12 December 2020

The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension

1 reference

12 December 2020

Angiotensin-converting enzyme inhibition delays pulmonary vascular neointimal formation

1 reference

12 December 2020

Chronic cor pulmonale. Etiology and management

1 reference

12 December 2020

Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?

1 reference

12 December 2020

BMP type II receptor is required for gastrulation and early development of mouse embryos

1 reference

12 December 2020

Toxicity of pyrrolizidine alkaloids

1 reference

12 December 2020

Beneficial hemodynamic effects of oral prostacyclin (PGI2) analogue, beraprost sodium, on a patient with primary pulmonary hypertension--a case report

1 reference

12 December 2020

40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats

1 reference

12 December 2020

Acute and chronic effects of T-1032, a novel selective phosphodiesterase type 5 inhibitor, on monocrotaline-induced pulmonary hypertension in rats

1 reference

12 December 2020

Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension

1 reference

12 December 2020

Clinical classification of pulmonary hypertension

1 reference

12 December 2020

Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability

1 reference

12 December 2020

Endothelial dysfunction in pulmonary hypertension

1 reference

12 December 2020

Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension.

1 reference

12 December 2020

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

1 reference

12 December 2020

Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors

1 reference

12 December 2020

Pulmonary arteritis produced in rat by feeding Crotalaria spectabilis

1 reference

12 December 2020

Recognition and management of pulmonary hypertension

1 reference

12 December 2020

The orally active ET(A) receptor antagonist (+)-(S)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphe nyl-propionic acid (LU 135252) prevents the development of pulmonary hypertension and endothelial metabolic dysfunction in monocrotaline-trea

1 reference

12 December 2020

Inhaled nitric oxide selectively decreases pulmonary artery pressure and pulmonary vascular resistance following acute massive pulmonary microembolism in piglets

1 reference

12 December 2020

Nonarteritic ischemic optic neuropathy developing soon after use of sildenafil (viagra): a report of seven new cases

1 reference

12 December 2020

Changes of zero-stress state of rat pulmonary arteries in hypoxic hypertension

1 reference

12 December 2020

Inhaled nitric oxide for the adult respiratory distress syndrome

1 reference

12 December 2020

Angiotensin II receptor expression and inhibition in the chronically hypoxic rat lung

1 reference

12 December 2020

Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats

1 reference

12 December 2020

Amlodipine inhibits the development of right ventricular hypertrophy and medial thickening of pulmonary arteries in a rat model of pulmonary hypertension

1 reference

12 December 2020

The efficacy of bosentan in inoperable chronic thromboembolic pulmonary hypertension: a 1-year follow-up study

1 reference

12 December 2020

Sildenafil inhibits hypoxia-induced pulmonary hypertension

1 reference

12 December 2020

Effectiveness of a nonselective ET(A/B) and a selective ET(A) antagonist in rats with monocrotaline-induced pulmonary hypertension

1 reference

12 December 2020

Increased lung preproET-1 and decreased ETB-receptor gene expression in fetal pulmonary hypertension

1 reference

12 December 2020

Addition of oral sildenafil to beraprost is a safe and effective therapeutic option for patients with pulmonary hypertension

1 reference

12 December 2020

Simvastatin treatment of pulmonary hypertension: an observational case series

1 reference

12 December 2020

Nitric oxide: its identity and role in blood pressure control

1 reference

12 December 2020

Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine

1 reference

12 December 2020

An evidence-based approach to the management of pulmonary arterial hypertension

1 reference

12 December 2020

Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension

1 reference

12 December 2020

The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS

1 reference

12 December 2020

BQ123, an ETA-receptor antagonist, attenuates hypoxic pulmonary hypertension in rats.

1 reference

12 December 2020

Physiological effects of high altitude on the pulmonary circulation

1 reference

12 December 2020

Prolonged administration of L-arginine ameliorates chronic pulmonary hypertension and pulmonary vascular remodeling in rats

1 reference

12 December 2020

Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension

1 reference

12 December 2020

Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension.

1 reference

12 December 2020

Selective vasodilation by nitric oxide inhalation during sustained pulmonary hypertension following recurrent microembolism in pigs.

1 reference

12 December 2020

Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus

1 reference

12 December 2020

A combination of oral sildenafil and beraprost ameliorates pulmonary hypertension in rats

1 reference

12 December 2020

Continuous intravenous epoprostenol for chronic thromboembolic pulmonary hypertension

1 reference

12 December 2020

Pulmonary artery remodeling differs in hypoxia- and monocrotaline-induced pulmonary hypertension

1 reference

12 December 2020

Statins as a newly recognized type of immunomodulator

1 reference

12 December 2020

Aerosolized Prostacyclin and Iloprost in Severe Pulmonary Hypertension

1 reference

12 December 2020

Hypoxia-induced structural changes in the media and adventitia of the rat hilar pulmonary artery and their regression

1 reference

12 December 2020

Triptolide attenuates pulmonary arterial hypertension and neointimal formation in rats

1 reference

12 December 2020

Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.

1 reference

12 December 2020

ETA-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in rat.

1 reference

12 December 2020

Response to bosentan in children with pulmonary hypertension

1 reference

12 December 2020

Failure of postnatal adaptation of the pulmonary circulation after chronic intrauterine pulmonary hypertension in fetal lambs

1 reference

12 December 2020

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study

1 reference

12 December 2020

Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans

1 reference

12 December 2020

Sequence of echocardiographic changes during development of right ventricular failure in rat

1 reference

12 December 2020

Pressure-induced connective tissue synthesis in pulmonary artery segments is dependent on intact endothelium

1 reference

12 December 2020

Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.

1 reference

12 December 2020

Clinical pharmacology of bosentan, a dual endothelin receptor antagonist

1 reference

12 December 2020

Attenuation of pulmonary vascular hypertension and cardiac hypertrophy with sitaxsentan sodium, an orally active ET(A) receptor antagonist

1 reference

12 December 2020

Ligating the ductus arteriosus before birth causes persistent pulmonary hypertension in the newborn lamb.

1 reference

12 December 2020

Attenuation of chronic hypoxic pulmonary hypertension by simvastatin

1 reference

12 December 2020

Sildenafil improves alveolar growth and pulmonary hypertension in hyperoxia-induced lung injury

1 reference

12 December 2020

Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.

1 reference

12 December 2020

Pulmonary vascular remodelling in hypoxic rats: effects of amlodipine, alone and with perindopril

1 reference

12 December 2020

Distribution of obstructive intimal lesions and their cellular phenotypes in chronic pulmonary hypertension. A morphometric and immunohistochemical study

1 reference

12 December 2020

Effects of vasodilators on hypoxic pulmonary vasoconstriction in normal man

1 reference

12 December 2020

Inhibition of tissue angiotensin-converting enzyme with quinapril reduces hypoxic pulmonary hypertension and pulmonary vascular remodeling

1 reference

12 December 2020

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

1 reference

12 December 2020

The orally active nonpeptide endothelin A-receptor antagonist A-127722 prevents and reverses hypoxia-induced pulmonary hypertension and pulmonary vascular remodeling in Sprague-Dawley rats

1 reference

12 December 2020

The structural basis of persistent pulmonary hypertension of the newborn infant

1 reference

12 December 2020

Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats

1 reference

12 December 2020

Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension

1 reference

12 December 2020

Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene.

1 reference

12 December 2020

Continuous low-dose NO inhalation does not prevent monocrotaline-induced pulmonary hypertension in rats

1 reference

12 December 2020

Effects of olmesartan medoxomil as an angiotensin II-receptor blocker in chronic hypoxic rats.

1 reference

12 December 2020

Sildenafil versus Endothelin Receptor Antagonist for Pulmonary Hypertension (SERAPH) study

1 reference

12 December 2020

Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension

1 reference

12 December 2020

Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

1 reference

12 December 2020

Aerosol gene transfer with inducible nitric oxide synthase reduces hypoxic pulmonary hypertension and pulmonary vascular remodeling in rats

1 reference

12 December 2020

Pulmonary hypertension--advances in medical and surgical interventions

1 reference

12 December 2020

Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension

1 reference

12 December 2020

Bosentan therapy for pulmonary arterial hypertension

1 reference

12 December 2020

Effects of Cilazapril, a Novel Angiotensin Converting Enzyme Inhibitor, on the Structure of Pulmonary Arteries of Rats Exposed to Chronic Hypoxia

1 reference

12 December 2020

Long-Term Treatment of Primary Pulmonary Hypertension with Aerosolized Iloprost, a Prostacyclin Analogue

1 reference

12 December 2020

Clinical classification of pulmonary hypertension.

1 reference

12 December 2020

Persistent pulmonary hypertension of the newborn infant

1 reference

12 December 2020

Partial reversibility of chronic pulmonary hypertension caused by pulmonary thromboembolic disease.

1 reference

12 December 2020

Involvement of cytochrome P450 3A in the metabolism and covalent binding of 14C-monocrotaline in rat liver microsomes.

1 reference

12 December 2020

The effects of chronic prostacyclin therapy on cardiac output and symptoms in primary pulmonary hypertension.

1 reference

12 December 2020

Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines.

1 reference

12 December 2020

Antithrombotic profile of iloprost in experimental models of in vivo platelet aggregation and thrombosis.

1 reference

12 December 2020

10.1007/S00210-006-0087-9

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

16932922