(Q36579350)

15 August 2017

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title

Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation (English)

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15 August 2017

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Ana C D'Alessio

1

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PubMed ID

16936820

15 August 2017

Moshe Szyf

series ordinal

2

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15 August 2017

1 August 2006

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Biochemistry and Cell Biology

15 August 2017

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15 August 2017

84

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15 August 2017

4

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15 August 2017

463-476

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TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters

15 August 2017

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Concurrent replication and methylation at mammalian origins of replication

21 January 2018

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Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

21 January 2018

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Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

21 January 2018

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Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

21 January 2018

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A mammalian protein with specific demethylase activity for mCpG DNA.

21 January 2018

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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

21 January 2018

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Myc represses transcription through recruitment of DNA methyltransferase corepressor

21 January 2018

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Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process

21 January 2018

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 January 2018

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Methylated DNA-binding protein 2 antisense inhibitors suppress tumourigenesis of human cancer cell lines in vitro and in vivo

21 January 2018

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

21 January 2018

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Demethylase activity is directed by histone acetylation

21 January 2018

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The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing

21 January 2018

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Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis.

21 January 2018

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Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.

21 January 2018

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CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2

21 January 2018

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GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability.

21 January 2018

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Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

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Promoter-specific activation and demethylation by MBD2/demethylase

21 January 2018

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Valproate induces replication-independent active DNA demethylation

21 January 2018

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Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

21 January 2018

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DNA methylation models histone acetylation

21 January 2018

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Interaction of HTLV-1 Tax and methyl-CpG-binding domain 2 positively regulates the gene expression from the hypermethylated LTR.

21 January 2018

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The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease

21 January 2018

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Hypomethylation distinguishes genes of some human cancers from their normal counterparts

21 January 2018

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Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.

21 January 2018

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Demethylation of genes in animal cells.

21 January 2018

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Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

21 January 2018

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Antithetic effects of MBD2a on gene regulation

21 January 2018

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DNA methyltransferase Dnmt1 associates with histone deacetylase activity

21 January 2018

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The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

21 January 2018

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Induction of Tumors in Mice by Genomic Hypomethylation

21 January 2018

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Histone modifying and chromatin remodelling enzymes in cancer and dysplastic syndromes

21 January 2018

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Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.

21 January 2018

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DNA methyltransferase inhibitors-state of the art.

21 January 2018

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Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion

21 January 2018

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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

21 January 2018

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21 January 2018

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Epigenetics, histone H3 variants, and the inheritance of chromatin states

21 January 2018

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Mechanisms of transformation by MLL.

21 January 2018

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21 January 2018

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Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase

21 January 2018

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De novo CpG island methylation in human cancer cells

21 January 2018

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Interplay between two epigenetic marks. DNA methylation and histone H3 lysine 9 methylation

21 January 2018

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5-Methylcytosine DNA glycosylase participates in the genome-wide loss of DNA methylation occurring during mouse myoblast differentiation

21 January 2018

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Reduced mRNA expression of the DNA demethylase, MBD2, in human colorectal and stomach cancers.

21 January 2018

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Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells.

21 January 2018

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Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

21 January 2018

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A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus

21 January 2018

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

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Roles of histone acetyltransferases and deacetylases in gene regulation

21 January 2018

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The many faces of histone lysine methylation

21 January 2018

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

21 January 2018

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MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

21 January 2018

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Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

21 January 2018

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MBDin, a novel MBD2-interacting protein, relieves MBD2 repression potential and reactivates transcription from methylated promoters.

21 January 2018

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Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

21 January 2018

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B cell-specific demethylation: a novel role for the intronic kappa chain enhancer sequence

21 January 2018

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The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation.

21 January 2018

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DNA methylation in Drosophila melanogaster.

21 January 2018

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Stage-specific chromosomal association of Drosophila dMBD2/3 during genome activation.

21 January 2018

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Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

21 January 2018

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ATP-dependent chromatin remodelling: SWI/SNF and Co. are on the job.

21 January 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Active demethylation of the paternal genome in the mouse zygote

21 January 2018

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Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo

21 January 2018

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Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis

21 January 2018

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Methylation and inhibition of expression of uPA by the RAS oncogene: divergence of growth control and invasion in breast cancer cells

21 January 2018

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Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

21 January 2018

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Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

21 January 2018

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Nucleosomal anatomy--where are the histones?

21 January 2018

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Histones in functional diversification. Core histone variants

21 January 2018

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DNA methylation is a reversible biological signal

21 January 2018

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Distribution of 5-methylcytosine in chromatin

21 January 2018

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DNA Methylation and Gene Function

21 January 2018

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DNA methylation patterns. Formation and function

21 January 2018

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Variations in DNA methylation during mouse cell differentiation in vivo and in vitro

21 January 2018

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A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

21 January 2018

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Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.

21 January 2018

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

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Deficiency of Mbd2 suppresses intestinal tumorigenesis

21 January 2018

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Chromatin modifier enzymes, the histone code and cancer

21 January 2018

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Active genes are tri-methylated at K4 of histone H3

21 January 2018

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Histone variants meet their match

21 January 2018

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Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling

21 January 2018

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Trichostatin A causes selective loss of DNA methylation in Neurospora

21 January 2018

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Tumor suppressor p53 represses transcription of RECQ4 helicase

21 January 2018

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Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

21 January 2018

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The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases.

21 January 2018

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The language of covalent histone modifications

21 January 2018

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Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter

21 January 2018

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Towards a pharmacology of DNA methylation

21 January 2018

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DNA methylation and demethylation as targets for anticancer therapy

21 January 2018

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Regulation of the DNA methylation machinery and its role in cellular transformation

21 January 2018

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Cellular and viral DNA hypomethylation associated with induction of Epstein-Barr virus lytic cycle

21 January 2018

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DNA demethylation and cancer: therapeutic implications.

21 January 2018

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DNA methylation and breast cancer

21 January 2018

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Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa

21 January 2018

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Histone demethylation by a family of JmjC domain-containing proteins

21 January 2018

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The absence of detectable methylated bases in Drosophila melanogaster DNA.

21 January 2018

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The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

21 January 2018

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Epigenetic programming by maternal behavior

21 January 2018

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Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene

21 January 2018

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Chromatin disruption and modification

21 January 2018

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Lsh, a modulator of CpG methylation, is crucial for normal histone methylation

21 January 2018

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Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

21 January 2018

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Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

21 January 2018

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Acetylation of adenovirus E1A regulates binding of the transcriptional corepressor CtBP.

21 January 2018

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Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss

21 January 2018

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5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence

21 January 2018

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Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene

21 January 2018

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Lsh is involved in de novo methylation of DNA

21 January 2018

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Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O06-090

1 reference

15 August 2017

1 reference

PubMed ID

16936820