(Q36580238)

15 August 2017

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis (English)

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genome-wide association study

15 August 2017

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46

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69

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138

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15 August 2017

Marjo-Riitta Järvelin

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153

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56

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André Uitterlinden

76

André G Uitterlinden

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Regina Fölster-Holst

64

Regina Fölster-Holst

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15 August 2017

108

Medea Imboden

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Eskil Kreiner-Møller

32

Eskil Kreiner-Møller

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15 August 2017

8

Klaus Bønnelykke

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15 August 2017

Alexessander Couto Alves

12

Alexessander Couto Alves

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15 August 2017

131

Mads Melbye

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Juha R. Pekkanen

Juha Pekkanen

66

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Ashish Kumar

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40

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Hansjörg Baurecht

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4

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Susanne Lau

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145

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Sylvain Sébert

Sylvain Sebert

67

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Lavinia Paternoster

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1

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Mariona Bustamante

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31

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Sheila Barton

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28

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David A Hinds

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149

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Christel M Middeldorp

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100

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Alan D. Irvine

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135

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Stephan Weidinger

Stephan Weidinger

154

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Caroline L. Relton

Caroline L Relton

111

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Craig E. Pennell

Craig E Pennell

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27

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Jacob P Thyssen

13

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Adnan Custovic

Adnan Custovic

114

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Keith Godfrey

Keith M Godfrey

128

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John W. Holloway

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123

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Hans Bisgaard

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Allan Linneberg

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142

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Markus M Nöthen

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144

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George Davey Smith

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48

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Jie Zheng

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47

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Frank Geller

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Joachim Heinrich

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152

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Carol A Wang

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129

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Wenche Nystad

113

Wenche Nystad

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15 August 2017

97

Bjarke Feenstra

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130

Dorret I Boomsma

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133

Deborah Jarvis

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141

Liesbeth Duijts

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118

Erik Melén

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117

Cilla Söderhäll

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Fernando Rivadeneira

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Albert Hofman

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Jordi Sunyer

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Momoko Horikoshi

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59

Annette Peters

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60

Annette Peters

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99

Jouke Jan Hottenga

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119

Carole Ober

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15 August 2017

96

Dirkje S Postma

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15 August 2017

44

Wendy L McArdle

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15 August 2017

51

Min Ae Lee-Kirsch

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15 August 2017

6

David P Strachan

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15 August 2017

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Vincent Wv Jaddoe

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14

Herman T den Dekker

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Hakon Hakonarson

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15 August 2017

49

Franz Rüschendorf

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15 August 2017

3

Johannes Waage

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15 August 2017

103

Tim Spector

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15 August 2017

61

Andre Franke

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15 August 2017

43

Michiaki Kubo

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Nicholas G Martin

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132

Gerard H Koppelman

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62

Wolfgang Lieb

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101

Pirro Hysi

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126

Nicole M Probst Hensch

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15 August 2017

2

Marie Standl

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82

Janina S Ried

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15 August 2017

102

Veronique Bataille

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15 August 2017

26

Cristina Venturini

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15 August 2017

Maria M Groen-Blokhuis

25

Maria M Groen-Blokhuis

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15 August 2017

22

Maria Pino Yanes

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15 August 2017

115

Scott T Weiss

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105

Elisabeth Thiering

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15 August 2017

29

Albert M Levin

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37

Supinda Bunyavanich

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15 August 2017

38

Rachel A Myers

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15 August 2017

41

Joyce Y Tung

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15 August 2017

104

Carla Mt Tiesler

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112

Ronny Myhre

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127

L Keoki Williams

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10

Atsushi Takahashi

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122

Bo Jacobsson

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15

Manuel A Ferreira

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17

Patrick Ma Sleiman

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Guy B Marks

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79

Melanie C Matheson

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15 August 2017

53

Georg Homuth

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15 August 2017

55

Elisabeth Mangold

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15 August 2017

20

Ingo Marenholz

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15 August 2017

Jorge Esparza-Gordillo

11

Jorge Esparza-Gordillo

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Anja Bauerfeind

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39

Anja Matanovic

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146

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15 August 2017

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15 August 2017

95

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15 August 2017

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74

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Australian Asthma Genetics Consortium

15 August 2017

81

Australian Asthma Genetics Consortium (AAGC)

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15 August 2017

Melanie Hotze

5

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15 August 2017

John A Curtin

7

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15 August 2017

Chao Tian

9

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15 August 2017

Elisabeth Altmaier

16

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15 August 2017

Feng Li Xiao

18

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15 August 2017

Juan R Gonzalez

19

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15 August 2017

Birgit Kalb

21

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15 August 2017

Cheng-Jian Xu

23

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15 August 2017

Lisbeth Carstensen

24

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15 August 2017

Ivan Curjuric

30

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15 August 2017

Gabrielle A Lockett

33

1 reference

15 August 2017

Gabrielle A Lockett

34

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15 August 2017

Jonas Bacelis

35

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15 August 2017

Jonas Bacelis

36

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15 August 2017

Tomomitsu Hirota

42

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15 August 2017

A J Henderson

45

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15 August 2017

Andreas Arnold

52

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15 August 2017

Carsten O Schmidt

54

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Thomas Keil

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15 August 2017

Elke Rodríguez

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15 August 2017

Natalija Novak

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68

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15 August 2017

Niels J Elbert

75

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Philip J Thompson

78

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15 August 2017

Colin F Robertson

80

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15 August 2017

Jin Li

83

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15 August 2017

Xian Bo Zuo

84

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15 August 2017

Xiao Dong Zheng

85

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15 August 2017

Xian Yong Yin

86

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15 August 2017

Liang Dan Sun

87

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15 August 2017

Maeve A McAleer

88

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15 August 2017

Grainne M O'Regan

89

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15 August 2017

Caoimhe Mr Fahy

90

1 reference

15 August 2017

Linda E Campbell

91

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15 August 2017

Milan Macek

92

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Michael Kurek

93

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15 August 2017

Donglei Hu

94

1 reference

15 August 2017

Badri Pahukasahasram

106

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15 August 2017

James J Yang

107

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15 August 2017

Scott Huntsman

109

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15 August 2017

Natàlia Vilor-Tejedor

110

1 reference

15 August 2017

Deborah A Meyers

116

1 reference

15 August 2017

Benjamin A Raby

120

1 reference

15 August 2017

Angela Simpson

121

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15 August 2017

Wh Irwin McLean

134

1 reference

15 August 2017

Young-Ae Lee

147

1 reference

15 August 2017

Mayumi Tamari

148

1 reference

15 August 2017

Daniel Glass

150

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15 August 2017

Sara J Brown

151

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15 August 2017

language of work or name

English

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publication date

19 October 2015

1 reference

15 August 2017

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15 August 2017

47

1 reference

15 August 2017

12

1 reference

15 August 2017

1449-1456

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describes a project that uses

15 August 2017

genome-wide association study

1 reference

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

inferred from title

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

The origins and functions of dendritic cells and macrophages in the skin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Bayesian test for colocalisation between pairs of genetic association studies using summary statistics

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Genetics of rheumatoid arthritis contributes to biology and drug discovery

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

9 September 2017

1 reference

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A Nondegenerate Code of Deleterious Variants in Mendelian Loci Contributes to Complex Disease Risk

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Bayesian refinement of association signals for 14 loci in 3 common diseases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Systematic localization of common disease-associated variation in regulatory DNA

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

An integrated encyclopedia of DNA elements in the human genome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Mapping cis- and trans-regulatory effects across multiple tissues in twins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

IL-7 in human health and disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Does "autoreactivity" play a role in atopic dermatitis?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

The use of the twin model to investigate the genetics and epigenetics of skin diseases with genomic, transcriptomic and methylation data

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Selection of self-reactive T cells in the thymus

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Filaggrin mutations associated with skin and allergic diseases.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Clan genomics and the complex architecture of human disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Langerhans cells in innate defense against pathogens

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

The NIH Roadmap Epigenomics Mapping Consortium

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A large-scale, consortium-based genomewide association study of asthma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Variants of DENND1B associated with asthma in children

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Ets-1 is a negative regulator of Th17 differentiation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

The role of microorganisms in atopic dermatitis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Environmental risk factors in paediatric inflammatory bowel diseases: a population based case control study

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Evaluating empirical bounds on complex disease genetic architecture

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Environmental factors and risk of developing paediatric inflammatory bowel disease -- a population based study 2007-2009.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Transgenic overexpression of G5PR that is normally augmented in centrocytes impairs the enrichment of high-affinity antigen-specific B cells, increases peritoneal B-1a cells, and induces autoimmunity in aged female mice.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Transethnic meta-analysis of genomewide association studies

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753676

Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study

20 September 2018

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A common variant on chromosome 11q13 is associated with atopic dermatitis.

20 September 2018

1 reference

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20 September 2018

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Variation in interleukin 7 receptor α chain (IL7R) influences risk of multiple sclerosis

20 September 2018

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https://api.crossref.org/works/10.1038%2FNG.3424

21 January 2018

1 reference

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Dupilumab treatment in adults with moderate-to-severe atopic dermatitis

4 December 2018

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12 December 2020

An association between ulcerative colitis and atopic dermatitis, diseases of impaired superficial barriers

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12 December 2020

Immunologic abnormalities exhibited in IL-7 transgenic mice with dermatitis

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12 December 2020

Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease

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12 December 2020

Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

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12 December 2020

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NG.3424

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

26482879

1 reference