(Q36582396)

15 August 2017

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title

Molecular therapies for malignant glioma (English)

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15 August 2017

Markus Hutterer

1

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PubMed ID

16944367

15 August 2017

Eberhard Gunsilius

series ordinal

2

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PubMed ID

16944367

15 August 2017

Guenther Stockhammer

series ordinal

3

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15 August 2017

1 June 2006

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Wiener Medizinische Wochenschrift

15 August 2017

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15 August 2017

156

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15 August 2017

11-12

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15 August 2017

351-363

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https://scigraph.springernature.com/pub.10.1007/s10354-006-0308-3

15 August 2017

0 references

cites work

Vascular endothelial growth factor in CSF: a biological marker for carcinomatous meningitis

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10354-006-0308-3

HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival

21 January 2018

1 reference

12 December 2020

Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study

1 reference

12 December 2020

Chemotherapy for the treatment of metastatic brain tumors

1 reference

12 December 2020

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy

1 reference

12 December 2020

In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats

1 reference

12 December 2020

Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer

1 reference

12 December 2020

Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer

1 reference

12 December 2020

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

1 reference

12 December 2020

Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma

1 reference

12 December 2020

Convection-enhanced delivery of macromolecules in the brain

1 reference

12 December 2020

The epidermal growth factor receptor: from mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia

1 reference

12 December 2020

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 1: growth factor and Ras signaling pathways

1 reference

12 December 2020

Combined inhibition of vascular endothelial growth factor and platelet-derived growth factor signaling: effects on the angiogenesis, microcirculation, and growth of orthotopic malignant gliomas.

1 reference

12 December 2020

AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection

1 reference

12 December 2020

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

1 reference

12 December 2020

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.

1 reference

12 December 2020

Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence.

1 reference

12 December 2020

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

1 reference

12 December 2020

Gene therapy for glioblastoma [correction of gliobestome] multiform: in vivo tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir

1 reference

12 December 2020

Isolation of putative progenitor endothelial cells for angiogenesis

1 reference

12 December 2020

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

1 reference

12 December 2020

Oncogenes and signal transduction

1 reference

12 December 2020

Intracerebral and intrathecal infusion of the TGF-beta 2-specific antisense phosphorothioate oligonucleotide AP 12009 in rabbits and primates: toxicology and safety.

1 reference

12 December 2020

Potent bystander effect in suicide gene therapy using neural stem cells transduced with herpes simplex virus thymidine kinase gene

1 reference

12 December 2020

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas

1 reference

12 December 2020

Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors.

1 reference

12 December 2020

Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development

1 reference

12 December 2020

HSV as a gene transfer vector for the nervous system

1 reference

12 December 2020

Malignant glioma: genetics and biology of a grave matter.

1 reference

12 December 2020

The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts

1 reference

12 December 2020

National survey of patterns of care for brain-tumor patients

1 reference

12 December 2020

Gene therapy and targeted toxins for glioma

1 reference

12 December 2020

Phase II trial of gefitinib in recurrent glioblastoma

1 reference

12 December 2020

Opportunities for the use of lentiviral vectors in human gene therapy

1 reference

12 December 2020

Rat glioma cell death induced by cationic liposome-mediated transfer of the herpes simplex virus thymidine kinase gene followed by ganciclovir treatment

1 reference

12 December 2020

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis

1 reference

12 December 2020

Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma

1 reference

12 December 2020

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1 reference

12 December 2020

Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas

1 reference

12 December 2020

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

1 reference

12 December 2020

Novel iodine-124 labeled EGFR inhibitors as potential PET agents for molecular imaging in cancer

1 reference

12 December 2020

Liposome-mediated gene transfer into established CNS cell lines, primary glial cells, and in vivo

1 reference

12 December 2020

Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo

1 reference

12 December 2020

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

1 reference

12 December 2020

Current and Future Gene Therapy for Malignant Gliomas

1 reference

12 December 2020

Transforming growth factor-beta-mediated autocrine growth regulation of gliomas as detected with phosphorothioate antisense oligonucleotides.

1 reference

12 December 2020

A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group

1 reference

12 December 2020

Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography.

1 reference

12 December 2020

Phase I trial of tipifarnib in patients with recurrent malignant glioma taking enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.

1 reference

12 December 2020

Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results

1 reference

12 December 2020

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

1 reference

12 December 2020

Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.

1 reference

12 December 2020

Gene therapy of experimental brain tumors using neural progenitor cells

1 reference

12 December 2020

Lentiviruses as vectors for CNS diseases

1 reference

12 December 2020

Chemotherapy and immunotherapy of malignant glioma: molecular mechanisms and clinical perspectives

1 reference

12 December 2020

Evidence from a leukaemia model for maintenance of vascular endothelium by bone-marrow-derived endothelial cells

1 reference

12 December 2020

Imaging in gene therapy of patients with glioma.

1 reference

12 December 2020

Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors

1 reference

12 December 2020

Primary and secondary glioblastomas: from concept to clinical diagnosis

1 reference

12 December 2020

Antiangiogenic gene therapy in a rat glioma model using a dominant-negative vascular endothelial growth factor receptor 2.

1 reference

12 December 2020

Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme

1 reference

12 December 2020

Imatinib and hydroxyurea in pretreated progressive glioblastoma multiforme: a patient series

1 reference

12 December 2020

Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma

1 reference

12 December 2020

Phase I and pharmacologic study of the tyrosine kinase inhibitor SU101 in patients with advanced solid tumors

1 reference

12 December 2020

Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity

1 reference

12 December 2020

Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development

1 reference

12 December 2020

The EGFR as a target for anticancer therapy--focus on cetuximab

1 reference

12 December 2020

Monitoring antiproliferative responses to kinase inhibitor therapy in mice with 3'-deoxy-3'-18F-fluorothymidine PET.

1 reference

12 December 2020

Fifty-one kilobase HSV-1 plasmid vector can be packaged using a helper virus-free system and supports expression in the rat brain

1 reference

12 December 2020

Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

1 reference

12 December 2020

Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs.

1 reference

12 December 2020

Growth factors and cancer

1 reference

12 December 2020

Vascular endothelial growth factor (VEGF) is elevated in brain tumor cysts and correlates with tumor progression

1 reference

12 December 2020

Targeted tumor therapy with the TGF-beta 2 antisense compound AP 12009.

1 reference

12 December 2020

Expression of activated epidermal growth factor receptors, Ras-guanosine triphosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens

1 reference

12 December 2020

Molecular pathways in the formation of gliomas.

1 reference

12 December 2020

10.1007/S10354-006-0308-3

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

16944367