(Q35641225)

English

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis

scientific article published on February 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

1 reference

Europe PubMed Central

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Herbert B Newton

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

1 February 2004

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Expert Review of Anticancer Therapy

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

105-128

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Malignant glioma: genetics and biology of a grave matter.

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Growth factors and cancer

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Function and regulation of ras.

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

TOR, a central controller of cell growth

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

PKB/AKT: functional insights from genetic models

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Identification of an amplified, highly expressed gene in a human glioma

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Medulloblastoma growth inhibition by hedgehog pathway blockade

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Small molecule modulation of Smoothened activity

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Glioma invasion in the central nervous system

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Expression and distribution of vascular endothelial growth factor protein in human brain tumors

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Mechanisms and future directions for angiogenesis-based cancer therapies

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Clinical translation of angiogenesis inhibitors

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Local endostatin treatment of gliomas administered by microencapsulated producer cells

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Continuous release of endostatin from microencapsulated engineered cells for tumor therapy

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Preclinical and clinical studies of MMP inhibitors in cancer

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential.

1 reference

https://api.crossref.org/works/10.1586%2F14737140.4.1.105

21 January 2018

Identifiers

10.1586/14737140.4.1.105

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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