(Q36585880)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Céline Schaeffer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Romain Perrier

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Angela Bachi

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Luca Rampoldi

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Martina Brunati

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Simone Perucca

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Ling Han

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Angela Cattaneo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Francesco Consolato

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Annapaola Andolfo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Eric Olinger

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Jianhao Peng

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Shuo Li

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Marcel Bokhove

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Edith Hummler

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Qingyu Wu

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Sara Santambrogio

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Olivier Devuyst

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

17 December 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

e08887

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

2 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4755741/fullTextXML

inferred from PubMed Central ID database lookup

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Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis

9 September 2017

1 reference

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Colon-specific deletion of epithelial sodium channel causes sodium loss and aldosterone resistance

9 September 2017

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Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membrane

9 September 2017

1 reference

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Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

9 September 2017

1 reference

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Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension

9 September 2017

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Uromodulin triggers IL-1β-dependent innate immunity via the NLRP3 inflammasome

9 September 2017

1 reference

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NIH Image to ImageJ: 25 years of image analysis

9 September 2017

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Proteolytic activation of pro-macrophage-stimulating protein by hepsin.

9 September 2017

1 reference

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Activation of the bumetanide-sensitive Na+,K+,2Cl- cotransporter (NKCC2) is facilitated by Tamm-Horsfall protein in a chloride-sensitive manner

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease.

9 September 2017

1 reference

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Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

9 September 2017

1 reference

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Atlas of gene expression in the mouse kidney: new features of glomerular parietal cells

9 September 2017

1 reference

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Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function

9 September 2017

1 reference

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Insights into egg coat assembly and egg-sperm interaction from the X-ray structure of full-length ZP3

9 September 2017

1 reference

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Progressive renal papillary calcification and ureteral stone formation in mice deficient for Tamm-Horsfall protein

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor

9 September 2017

1 reference

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A versatile viral system for expression and depletion of proteins in mammalian cells

9 September 2017

1 reference

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Calreticulin enhances B2 bradykinin receptor maturation and heterodimerization

9 September 2017

1 reference

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Multiple loci associated with indices of renal function and chronic kidney disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Urinary uromodulin carries an intact ZP domain generated by a conserved C-terminal proteolytic cleavage

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Mass spectrometric evidence that proteolytic processing of rainbow trout egg vitelline envelope proteins takes place on the egg.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Identification of hepatocyte growth factor activator inhibitor-1B as a potential physiological inhibitor of prostasin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Zona pellucida domain proteins.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

A duplicated motif controls assembly of zona pellucida domain proteins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Tamm-Horsfall glycoprotein: biology and clinical relevance

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Structural characterization of native mouse zona pellucida proteins using mass spectrometry

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

The ZP domain is a conserved module for polymerization of extracellular proteins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

A new mathematical model for relative quantification in real-time RT-PCR

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Dipeptidyl-peptidase IV (CD26)--role in the inactivation of regulatory peptides

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Urinary secretion and extracellular aggregation of mutant uromodulin isoforms.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Analysis of uromodulin polymerization provides new insights into the mechanisms regulating ZP domain-mediated protein assembly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Matrix metalloproteinase 13 (MMP13) and tissue inhibitor of matrix metalloproteinase 1 (TIMP1), regulated by the MAPK pathway, are both necessary for Madin-Darby canine kidney tubulogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Long term metabolic arrest and recovery of HEK293 spheroids involves NF-kappaB signaling and sustained JNK activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

The MUC1 SEA module is a self-cleaving domain.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Gene expression profiles in HEK-293 cells with low or high store-operated calcium entry: can regulatory as well as regulated genes be identified?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Polarized GP2 secretion in MDCK cells via GPI targeting and apical membrane-restricted proteolysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Calcium signaling-related proteins are associated with broncho-pulmonary dysplasia progression.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Role of hepsin in factor VII activation in zebrafish

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Establishment of an in vivo model facilitates B2 receptor protein maturation and heterodimerization

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Prostasin attenuates inducible nitric oxide synthase expression in lipopolysaccharide-induced urinary bladder inflammation.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

A conditional allele at the mouse channel activating protease 1 (Prss8) gene locus.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755741

The primary structure of high molecular mass urokinase from human urine. The complete amino acid sequence of the A chain

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26673890

12 December 2020

inferred from PubMed ID database lookup

Molecular basis for oviductin-mediated processing from gp43 to gp41, the predominant glycoproteins of Xenopus egg envelopes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26673890

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.7554/ELIFE.08887

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

release_oxj57wbtyre7vdg7fuwzwmyffu

2 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/oxj57wbtyre7vdg7fuwzwmyffu

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26673890%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference