(Q36591241)

English

Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder.

scientific article published on 13 November 2012

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scholarly article

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17 February 2020

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Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder (English)

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17 February 2020

genome-wide association study

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17 February 2020

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17 February 2020

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17 February 2020

Jordan W Smoller

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17 February 2020

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P H Lee

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17 February 2020

J-Y Jung

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17 February 2020

E Rueckert

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17 February 2020

S Haddad

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17 February 2020

C E Mayerfeld

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17 February 2020

A C Heath

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17 February 2020

M L Pergadia

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17 February 2020

P A F Madden

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17 February 2020

P Sklar

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17 February 2020

S M Purcell

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17 February 2020

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13 November 2012

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17 February 2020

Translational Psychiatry

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17 February 2020

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17 February 2020

e184

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17 February 2020

https://scigraph.springernature.com/pub.10.1038/tp.2012.95

0 references

INRICH: interval-based enrichment analysis for genome-wide association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

A mega-analysis of genome-wide association studies for major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

A new lead from genetic studies in depressed siblings: assessing studies of chromosome 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

The neuronal transporter gene SLC6A15 confers risk to major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Overview of the genetics of major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Genome-wide association scan of trait depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits

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9 September 2017

Genetics of unipolar major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Poor replication of candidate genes for major depressive disorder using genome-wide association data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Genome-wide association study of recurrent early-onset major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Rapid enhancement of glutamatergic neurotransmission in bipolar depression following treatment with riluzole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Common variants in the trichohyalin gene are associated with straight hair in Europeans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Common genetic variants on 5p14.1 associate with autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Ketamine and the next generation of antidepressants with a rapid onset of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals

1 reference

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9 September 2017

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

1 reference

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9 September 2017

The molecular neurobiology of depression

1 reference

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Practical aspects of imputation-driven meta-analysis of genome-wide association studies

1 reference

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Increased anterior cingulate cortical activity in response to fearful faces: a neurophysiological biomarker that predicts rapid antidepressant response to ketamine.

1 reference

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Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

1 reference

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9 September 2017

The role of glutamate in mood disorders: results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects

1 reference

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Pathway-based approaches for analysis of genomewide association studies

1 reference

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1 reference

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1 reference

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Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence

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Epidemiology of major depressive disorder: results from the National Epidemiologic Survey on Alcoholism and Related Conditions

1 reference

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9 September 2017

Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8

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9 September 2017

Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3565768

9 September 2017

Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system

1 reference

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1 reference

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Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders

1 reference

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28 June 2018

A genome-wide significant linkage for severe depression on chromosome 3: the depression network study

1 reference

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20 September 2018

Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression.

1 reference

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20 September 2018

Genome-wide association study of major recurrent depression in the U.K. population.

1 reference

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20 September 2018

Cerebral metabolic changes in a depression-like rat model of chronic forced swimming studied by ex vivo high resolution 1H magnetic resonance spectroscopy.

1 reference

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20 September 2018

Increased levels of glutamate in brains from patients with mood disorders.

1 reference

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20 September 2018

Evaluation of the mGlu8 receptor as a putative therapeutic target in schizophrenia.

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20 September 2018

Glutamate agonists activate the hypothalamic-pituitary-adrenal axis through hypothalamic paraventricular nucleus but not through vasopressinerg neurons

1 reference

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20 September 2018

Glutamate-hypothalamic-pituitary-adrenal axis interactions: implications for mood and anxiety disorders.

1 reference

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20 September 2018

Increased anxiety-related behavior in mice deficient for metabotropic glutamate 8 (mGlu8) receptor

1 reference

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20 September 2018

Meta-analysis supports association between serotonin transporter (5-HTT) and suicidal behavior.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.95

21 January 2018

Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.95

21 January 2018

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10.1038/TP.2012.95

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149448%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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Europe PubMed Central

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17 February 2020

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Europe PubMed Central

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17 February 2020

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