(Q36591370)

English

IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro

scientific article published on 8 January 2008

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro (English)

1 reference

Europe PubMed Central

15 August 2017

0 references

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1 reference

based on heuristic

inferred from title

chronic lymphocytic leukemia

1 reference

based on heuristic

inferred from title

2

object named as

Julie Roda

1 reference

Europe PubMed Central

15 August 2017

16

object named as

John C Byrd

1 reference

Europe PubMed Central

15 August 2017

Michael A Caligiuri

13

object named as

Michael A Caligiuri

1 reference

Europe PubMed Central

15 August 2017

5

object named as

Trupti Joshi

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Europe PubMed Central

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12

object named as

Carolyn Cheney

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Europe PubMed Central

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1

object named as

Aruna Gowda

1 reference

Europe PubMed Central

15 August 2017

9

object named as

David Jarjoura

1 reference

Europe PubMed Central

15 August 2017

8

object named as

Amy Lehman

1 reference

Europe PubMed Central

15 August 2017

Susheela Tridandapani

14

object named as

Susheela Tridandapani

1 reference

Europe PubMed Central

15 August 2017

Natarajan Muthusamy

15

object named as

Natarajan Muthusamy

1 reference

Europe PubMed Central

15 August 2017

4

object named as

Asha Ramanunni

1 reference

Europe PubMed Central

15 August 2017

Wayne Kindsvogel

11

object named as

Wayne Kindsvogel

1 reference

Europe PubMed Central

15 August 2017

Syed-Rehan A Hussain

3

object named as

Syed-Rehan A Hussain

1 reference

Europe PubMed Central

15 August 2017

author name string

Susan Schmidt

6

1 reference

Europe PubMed Central

15 August 2017

Xiaoli Zhang

7

1 reference

Europe PubMed Central

15 August 2017

William E Carson

10

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Europe PubMed Central

15 August 2017

language of work or name

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publication date

8 January 2008

1 reference

Europe PubMed Central

15 August 2017

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Europe PubMed Central

15 August 2017

111

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Europe PubMed Central

15 August 2017

4723-4730

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Europe PubMed Central

15 August 2017

9

1 reference

Europe PubMed Central

15 August 2017

Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

9 September 2017

Immunostimulatory oligodeoxynucleotides induce apoptosis of B cell chronic lymphocytic leukemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

9 September 2017

STAT1: a modulator of chemotherapy-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

9 September 2017

Randomized phase 2 study of fludarabine with concurrent versus sequential treatment with rituximab in symptomatic, untreated patients with B-cell chronic lymphocytic leukemia: results from Cancer and Leukemia Group B 9712 (CALGB 9712).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

9 September 2017

Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

9 September 2017

Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

9 September 2017

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

9 September 2017

National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

9 September 2017

Interleukin-21 enhances NK cell activation in response to antibody-coated targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

30 September 2017

Effect of alemtuzumab on neoplastic B cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

30 September 2017

IL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

30 September 2017

Rituximab-mediated antibody-dependent cellular cytotoxicity against neoplastic B cells is stimulated strongly by interleukin-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

30 September 2017

Interleukin-21 is a growth and survival factor for human myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

30 September 2017

Multiparametric flow cytometric analysis of inter-patient variation in STAT1 phosphorylation following interferon Alfa immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

28 June 2018

Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

28 June 2018

Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

20 September 2018

IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343602

20 September 2018

IL-21 induces the apoptosis of resting and activated primary B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18182577

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. The French Cooperative Group on CLL

1 reference

https://pubmed.ncbi.nlm.nih.gov/18182577

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapeutic options in chronic lymphocytic leukemia: a meta-analysis of the randomized trials. CLL Trialists' Collaborative Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/18182577

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2007-07-099531

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

ResearchGate publication ID

0 references

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