(Q36592753)

15 August 2017

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title

Genetic, ethnic, and gender differences in the pharmacokinetics of antiretroviral agents (English)

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15 August 2017

anti-retroviral agent

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1 reference

Chantal Csajka

2

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Amalio Telenti

series ordinal

3

object named as

Amalio Telenti

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15 August 2017

Margalida Rotger

1

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15 August 2017

1 September 2006

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15 August 2017

Current HIV/AIDS reports

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15 August 2017

3

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15 August 2017

3

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15 August 2017

118-125

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https://scigraph.springernature.com/pub.10.1007/bf02696655

15 August 2017

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cites work

Pharmacokinetic variability caused by gender: do women have higher indinavir exposure than men?

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02696655

Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissues

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02696655

Population pharmacokinetics of tenofovir in human immunodeficiency virus-infected patients taking highly active antiretroviral therapy

21 January 2018

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12 December 2020

Population pharmacokinetics and exposure-response relationship of enfuvirtide in treatment-experienced human immunodeficiency virus type 1-infected patients

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12 December 2020

Differences in plasma binding of drugs between Caucasians and Chinese subjects.

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12 December 2020

Population pharmacokinetics of nevirapine in an unselected cohort of HIV-1-infected individuals

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12 December 2020

Population pharmacokinetics and pharmacodynamics of efavirenz, nelfinavir, and indinavir: Adult AIDS Clinical Trial Group Study 398.

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Sex-based differences in saquinavir pharmacology and virologic response in AIDS Clinical Trials Group Study 359.

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Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study

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12 December 2020

Population pharmacokinetics of lopinavir in combination with ritonavir in HIV-1-infected patients

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12 December 2020

Population pharmacokinetic analysis of indinavir in HIV-infected patient treated with a stable antiretroviral therapy

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12 December 2020

Effect of coadministration of nelfinavir, indinavir, and saquinavir on the pharmacokinetics of amprenavir

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12 December 2020

A population pharmacokinetic analysis of nelfinavir mesylate in human immunodeficiency virus-infected patients enrolled in a phase III clinical trial

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Research with stored biological samples: what do research participants want?

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Nevirapine and efavirenz pharmacokinetics and covariate analysis in the 2NN study.

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12 December 2020

Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

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12 December 2020

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'Racial' differences in genetic effects for complex diseases

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12 December 2020

Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz

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12 December 2020

Population genetic structure of variable drug response

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12 December 2020

Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism

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12 December 2020

Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR

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12 December 2020

Association of the CYP3A5 A6986G (CYP3A5*3) polymorphism with saquinavir pharmacokinetics

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12 December 2020

Population pharmacokinetics of efavirenz in an unselected cohort of HIV-1-infected individuals

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12 December 2020

Influence of ABCB1, ABCC1, ABCC2, and ABCG2 haplotypes on the cellular exposure of nelfinavir in vivo

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12 December 2020

Twenty-six novel single nucleotide polymorphisms and their frequencies of the NR1I3 (CAR) gene in a Japanese population.

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12 December 2020

Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects

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12 December 2020

Population pharmacokinetics of indinavir in patients infected with human immunodeficiency virus

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12 December 2020

Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels

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12 December 2020

Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

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12 December 2020

Population pharmacokinetic meta-analysis with efavirenz

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12 December 2020

Steady-state pharmacokinetics of a double-boosting regimen of saquinavir soft gel plus lopinavir plus minidose ritonavir in human immunodeficiency virus-infected adults

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12 December 2020

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

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Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

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The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants

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Differences between blacks and whites in plasma protein binding of drugs.

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Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability

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Population pharmacokinetics of indinavir alone and in combination with ritonavir in HIV-1-infected patients

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12 December 2020

Sex differences in pharmacokinetics and pharmacodynamics

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12 December 2020

In vivo effect of alpha(1)-acid glycoprotein on pharmacokinetics of amprenavir, a human immunodeficiency virus protease inhibitor

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12 December 2020

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

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12 December 2020

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz

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12 December 2020

Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens.

1 reference

12 December 2020

A multi-investigator/institutional DNA bank for AIDS-related human genetic studies: AACTG Protocol A5128.

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12 December 2020

Oral administration of a low dose of midazolam (75 microg) as an in vivo probe for CYP3A activity

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12 December 2020

Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.

1 reference

12 December 2020

Population pharmacokinetics of nevirapine, zidovudine, and didanosine in human immunodeficiency virus-infected patients. The National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators

1 reference

12 December 2020

Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection

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12 December 2020

Frequency of C3435T polymorphism of MDR1 gene in African people

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12 December 2020

The CYP2C19 enzyme polymorphism

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12 December 2020

Pharmacokinetics of nevirapine and lamivudine in patients with HIV-1 infection

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12 December 2020

Antiviral dynamics and sex differences of zidovudine and lamivudine triphosphate concentrations in HIV-infected individuals

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12 December 2020

Identifiers

DOI

10.1007/BF02696655

1 reference

15 August 2017

1 reference

PubMed ID

16970838