(Q36597042)

English

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

scientific article published on 22 October 2012

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance (English)

1 reference

Europe PubMed Central

15 August 2017

David J. Bearss

15

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Europe PubMed Central

15 August 2017

Kevin R. Coombes

32

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15 August 2017

Ignacio I Wistuba

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object named as

Ignacio I Wistuba

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34

object named as

John V Heymach

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object named as

Roy S Herbst

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George R Blumenschein

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object named as

George R Blumenschein

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Europe PubMed Central

15 August 2017

Gordon B. Mills

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object named as

Gordon B Mills

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object named as

Scott M Lippman

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object named as

K Kian Ang

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15 August 2017

author name string

Lauren Averett Byers

1

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Europe PubMed Central

15 August 2017

Lixia Diao

2

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Europe PubMed Central

15 August 2017

Jing Wang

3

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15 August 2017

Pierre Saintigny

4

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15 August 2017

Luc Girard

5

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15 August 2017

Michael Peyton

6

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15 August 2017

Li Shen

7

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Youhong Fan

8

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Uma Giri

9

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Praveen K Tumula

10

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Monique B Nilsson

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Jayanthi Gudikote

12

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Hai Tran

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Robert J G Cardnell

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Steven L Warner

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Jason M Foulks

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Steven B Kanner

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Varsha Gandhi

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15 August 2017

Nancy Krett

20

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Steven T Rosen

21

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15 August 2017

Edward S Kim

22

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J Jack Lee

25

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Waun K Hong

29

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15 August 2017

John N Weinstein

30

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15 August 2017

John D Minna

33

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15 August 2017

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publication date

22 October 2012

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15 August 2017

Clinical Cancer Research

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15 August 2017

19

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279-290

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1

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15 August 2017

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

1 reference

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The BATTLE trial: personalizing therapy for lung cancer

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ZEB1-responsive genes in non-small cell lung cancer

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Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival

1 reference

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Epithelial-mesenchymal transitions in development and disease

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The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target

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Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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Identifiers

10.1158/1078-0432.CCR-12-1558

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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