(Q36606137)

15 August 2017

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title

Hepatobiliary transporters and drug-induced cholestasis (English)

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15 August 2017

Christiane Pauli-Magnus

series ordinal

1

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PubMed ID

17006912

15 August 2017

Peter J Meier

series ordinal

2

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PubMed ID

17006912

15 August 2017

language of work or name

English

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publication date

1 October 2006

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15 August 2017

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15 August 2017

44

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15 August 2017

778-787

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15 August 2017

4

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Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate

15 August 2017

1 reference

Bile salt transporters: molecular characterization, function, and regulation

21 January 2018

1 reference

Hepatotoxicity of commonly used drugs: nonsteroidal anti-inflammatory drugs, antihypertensives, antidiabetic agents, anticonvulsants, lipid-lowering agents, psychotropic drugs.

21 January 2018

1 reference

7 January 2021

Drug-induced liver injury: mechanisms and test systems.

1 reference

7 January 2021

Criteria of drug-induced liver disorders. Report of an international consensus meeting

1 reference

7 January 2021

The sodium bile salt cotransport family SLC10

1 reference

7 January 2021

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

1 reference

7 January 2021

Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin

1 reference

7 January 2021

Identification of phalloidin uptake systems of rat and human liver

1 reference

7 January 2021

Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins

1 reference

7 January 2021

Molecular characterization and inhibition of amanitin uptake into human hepatocytes

1 reference

7 January 2021

The SLC22 drug transporter family

1 reference

7 January 2021

A family of drug transporters: the multidrug resistance-associated proteins.

1 reference

7 January 2021

Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism

1 reference

7 January 2021

The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp

1 reference

7 January 2021

Bile acid-induced negative feedback regulation of the human ileal bile acid transporter

1 reference

7 January 2021

Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression

1 reference

7 January 2021

Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1 alpha

1 reference

7 January 2021

Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor

1 reference

7 January 2021

Sodium taurocholate cotransporting polypeptide is a serine, threonine phosphoprotein and is dephosphorylated by cyclic adenosine monophosphate

1 reference

7 January 2021

Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface.

1 reference

7 January 2021

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

1 reference

7 January 2021

FIC1: another bile salt carrier within the enterohepatic circulation?

1 reference

7 January 2021

Enterohepatic bile salt transporters in normal physiology and liver disease

1 reference

7 January 2021

Bile salt transporters

1 reference

7 January 2021

The human bile salt export pump: characterization of substrate specificity and identification of inhibitors

1 reference

7 January 2021

Functional expression of the canalicular bile salt export pump of human liver

1 reference

7 January 2021

Biliary lipids, water and cholesterol gallstones

1 reference

7 January 2021

MRP2 and 3 in health and disease

1 reference

7 January 2021

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

1 reference

7 January 2021

Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

1 reference

7 January 2021

ABCG2 transports sulfated conjugates of steroids and xenobiotics

1 reference

7 January 2021

Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin

1 reference

7 January 2021

Genetic defenses against noncholesterol sterols.

1 reference

7 January 2021

The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice.

1 reference

7 January 2021

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

1 reference

7 January 2021

Farnesoid X Receptor Activates Transcription of the Phospholipid Pump MDR3

1 reference

7 January 2021

Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump

1 reference

7 January 2021

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

1 reference

7 January 2021

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

7 January 2021

St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4

1 reference

7 January 2021

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

1 reference

7 January 2021

Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

1 reference

7 January 2021

Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats

1 reference

7 January 2021

The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver

1 reference

7 January 2021

Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles

1 reference

7 January 2021

Expression and localization of the multidrug resistance proteins MRP2 and MRP3 in human gallbladder epithelia

1 reference

7 January 2021

Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties

1 reference

7 January 2021

OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia

1 reference

7 January 2021

Enterohepatic transport of bile salts and genetics of cholestasis

1 reference

7 January 2021

Vanishing bile duct syndrome in drug-induced liver disease

1 reference

7 January 2021

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

1 reference

7 January 2021

Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

1 reference

7 January 2021

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions

1 reference

7 January 2021

Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat.

1 reference

7 January 2021

MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping

1 reference

7 January 2021

Contribution of mrp2 in alterations of canalicular bile formation by the endothelin antagonist bosentan

1 reference

7 January 2021

Importance of P-glycoprotein at blood-tissue barriers

1 reference

7 January 2021

Sulindac is excreted into bile by a canalicular bile salt pump and undergoes a cholehepatic circulation in rats

1 reference

7 January 2021

Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver.

1 reference

7 January 2021

Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.

1 reference

7 January 2021

Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.

1 reference

7 January 2021

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

1 reference

7 January 2021

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

1 reference

7 January 2021

Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics

1 reference

7 January 2021

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

1 reference

7 January 2021

Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.

1 reference

7 January 2021

Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis

1 reference

7 January 2021

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

1 reference

7 January 2021

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

1 reference

7 January 2021

Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy

1 reference

7 January 2021

The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood

1 reference

7 January 2021

Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy

1 reference

7 January 2021

BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis.

1 reference

7 January 2021

Recurrent familial prolonged intrahepatic cholestasis of pregnancy associated with chronic liver disease

1 reference

7 January 2021

Hepatobiliary complications of oral contraceptives

1 reference

7 January 2021

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

7 January 2021

The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells

1 reference

7 January 2021

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

1 reference

7 January 2021

Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lymphoblastic leukemia.

1 reference

7 January 2021

Influence of functional polymorphisms of the MDR1 gene on vincristine pharmacokinetics in childhood acute lymphoblastic leukemia.

1 reference

7 January 2021

Identification of functionally variant MDR1 alleles among European Americans and African Americans

1 reference

7 January 2021

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine

1 reference

7 January 2021

No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects

1 reference

7 January 2021

ATP binding cassette transporter G5 and G8 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin

1 reference

7 January 2021

Single nucleotide polymorphisms modify the transporter activity of ABCG2.

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.21359

1 reference

15 August 2017

1 reference

PubMed ID

17006912