(Q36610257)

15 August 2017

High-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer (English)

1 reference

15 August 2017

1 reference

A Kallioniemi

4

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author name string

J Pärssinen

series ordinal

1

1 reference

15 August 2017

T Kuukasjärvi

series ordinal

2

1 reference

15 August 2017

R Karhu

series ordinal

3

1 reference

15 August 2017

language of work or name

English

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publication date

13 March 2007

1 reference

British Journal of Cancer

15 August 2017

1 reference

15 August 2017

96

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15 August 2017

8

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15 August 2017

1258-1264

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6603692

15 August 2017

0 references

cites work

RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes

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Breast tumor copy number aberration phenotypes and genomic instability

30 September 2017

1 reference

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Comprehensive profiling of 8p11-12 amplification in breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Amplification of Cyclin L1 is associated with lymph node metastases in head and neck squamous cell carcinoma (HNSCC)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

High-resolution analysis of gene copy number alterations in human prostate cancer using CGH on cDNA microarrays: impact of copy number on gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

30 September 2017

Chromosomal instability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

High-throughput copy number analysis of 17q23 in 3520 tissue specimens by fluorescence in situ hybridization to tissue microarrays

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Overexpressed genes/ESTs and characterization of distinct amplicons on 17q23 in breast cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

17q23 amplifications in breast cancer involve the PAT1, RAD51C, PS6K, and SIGma1B genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Multiple genes at 17q23 undergo amplification and overexpression in breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Detecting activation of ribosomal protein S6 kinase by complementary DNA and tissue microarray analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Chromosomal instability and cytoskeletal defects in oral cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

The HER-2/neu oncogene: prognostic factor, predictive factor and target for therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Analysis of genomic alterations in benign, atypical, and anaplastic meningiomas: toward a genetic model of meningioma progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Amplification of N-myc as a prognostic marker for patients with neuroblastoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Genetic aberrations detected by comparative genomic hybridization predict outcome in node-negative breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Amplification of a 280-Kilobase Core Region at the ERBB2 Locus Leads to Activation of Two Hypothetical Proteins in Breast Cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Association of 17q21-q24 gain in ovarian clear cell adenocarcinomas with poor prognosis and identification of PPM1D and APPBP2 as likely amplification targets

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

PPM1D is a potential target for 17q gain in neuroblastoma

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Primary small-cell lung carcinomas and their metastases are characterized by a recurrent pattern of genetic alterations.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Impact of DNA amplification on gene expression patterns in breast cancer

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360139

Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma

21 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6603692

Chromosomal losses of regions on 5q and lack of high-level amplifications at 8q24 are associated with favorable prognosis for ovarian serous carcinoma

21 January 2018

1 reference

12 December 2020

17q21-qter trisomy is an indicator of poor prognosis in acute myelogenous leukemia

1 reference

12 December 2020

Structural analysis of the 17q22-23 amplicon identifies several independent targets of amplification in breast cancer cell lines and tumors

1 reference

12 December 2020

New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays

1 reference

12 December 2020

Detailed gene copy number and RNA expression analysis of the 17q12-23 region in primary breast cancers

1 reference

12 December 2020

Mapping of multiple DNA gains and losses in primary small cell lung carcinomas by comparative genomic hybridization

1 reference

12 December 2020

Detection of DNA amplification in 17 primary breast carcinomas with homogeneously staining regions by a modified comparative genomic hybridization technique

1 reference

12 December 2020

Mapping of chromosomal imbalances in pancreatic carcinoma by comparative genomic hybridization

1 reference

12 December 2020

Detection of chromosomal DNA gains and losses in testicular germ cell tumors by comparative genomic hybridization

1 reference

12 December 2020

Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization

1 reference

12 December 2020

Comparative genomic hybridization (CGH) analysis of neuroblastomas--an important methodological approach in paediatric tumour pathology

1 reference

12 December 2020

Marked genetic differences between stage pTa and stage pT1 papillary bladder cancer detected by comparative genomic hybridization

1 reference

12 December 2020

Comparative genomic hybridization detects frequent overrepresentation of chromosomal material from 3q26, 8q24, and 20q13 in human ovarian carcinomas

1 reference

12 December 2020

Increased copy number at 17q22-q24 by CGH in breast cancer is due to high-level amplification of two separate regions

1 reference

12 December 2020

Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer

1 reference

12 December 2020

Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer

1 reference

12 December 2020

Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6603692

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.BJC.6603692

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

17353917

1 reference