(Q36616577)

15 August 2017

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title

Runx2 and dental development (English)

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15 August 2017

Simon Camilleri

1

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15 August 2017

Fraser McDonald

series ordinal

2

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15 August 2017

publication date

1 October 2006

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European Journal of Oral Sciences

15 August 2017

published in

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15 August 2017

volume

114

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15 August 2017

issue

5

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15 August 2017

page(s)

361-373

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Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

15 August 2017

cites work

1 reference

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

21 January 2018

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Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

21 January 2018

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Mutation analysis of core binding factor A1 in patients with cleidocranial dysplasia

21 January 2018

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AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

21 January 2018

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Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor

21 January 2018

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Cbfbeta interacts with Runx2 and has a critical role in bone development

21 January 2018

1 reference

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Core-binding factor beta interacts with Runx2 and is required for skeletal development

21 January 2018

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Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF.

21 January 2018

1 reference

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Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation

21 January 2018

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Osteoblasts: novel roles in orchestration of skeletal architecture

21 January 2018

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Bone Matrix Proteins: More Than Markers

21 January 2018

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Matrix proteins versus cytokines in the regulation of osteoblast function and bone formation

21 January 2018

1 reference

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

21 January 2018

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Enhanced activity of osteoblast differentiation factor (PEBP2alphaA2/CBFa1) in affected sutural osteoblasts from patients with nonsyndromic craniosynostosis

21 January 2018

1 reference

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High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage

21 January 2018

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Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

CBFA1 and topoisomerase I mRNA levels decline during cellular aging of human trabecular osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Bone morphogenetic protein-2 stimulates Runx2 acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

A molecular pathogenesis for transcription factor associated poly-alanine tract expansions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Association with the nuclear matrix and interaction with Groucho and RUNX proteins regulate the transcription repression activity of the basic helix loop helix factor Hes1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Transcriptional co-repressors of Runx2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Groucho homologue Grg5 interacts with the transcription factor Runx2-Cbfa1 and modulates its activity during postnatal growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

A twist code determines the onset of osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Cbfa1 isoform overexpression upregulates osteocalcin gene expression in non-osteoblastic and pre-osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Cbfa1 isoforms exert functional differences in osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Differential expression patterns of Runx2 isoforms in cranial suture morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Runx2 regulates FGF2-induced Bmp2 expression during cranial bone development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Type II/III Runx2/Cbfa1 is required for tooth germ development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

IRES-dependent translational control of Cbfa1/Runx2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Conservation and expression of an alternative 3' exon of Runx2 encoding a novel proline-rich C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Induction of Osteoclast Differentiation by Runx2 through Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin Regulation and Partial Rescue of Osteoclastogenesis in Runx2–/– Mice by RANKL Transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Runx-2 is not essential for the vitamin D-regulated expression of RANKL and osteoprotegerin in osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Osteoclast signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Phenotypic changes in dentition of Runx2 homozygote-null mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Role of Cbfa1 in ameloblastin gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Cleidocranial dysplasia: a light microscope, electron microscope, and crystallographic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Detection of dentin sialoprotein in rat periodontium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Differential regulation of dentin sialophosphoprotein expression by Runx2 during odontoblast cytodifferentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Differentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Altered gene expression in human cleidocranial dysplasia dental pulp cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

MEPE is downregulated as dental pulp stem cells differentiate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Tooth eruption and cementum formation in the Runx2/Cbfa1 heterozygous mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Expression of cementum-derived attachment protein in bovine tooth germ during cementogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

S100A4 inhibition by RNAi up-regulates osteoblast related genes in periodontal ligament cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Delayed tooth eruption and suppressed osteoclast number in the eruption pathway of heterozygous Runx2/Cbfa1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Somatic development in cleidocranial dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Characteristics of jaw growth in cleidocranial dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Osteoclastogenesis during mouse tooth germ development is mediated by receptor activator of NFKappa-B ligand (RANKL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

CSF-1, RANKL and OPG regulate osteoclastogenesis during murine tooth eruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Functional analysis of RUNX2 mutations in cleidocranial dysplasia: novel insights into genotype–phenotype correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Six novel mutations of the RUNX2 gene in Italian patients with cleidocranial dysplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Restriction of sonic hedgehog signalling during early tooth development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Genetic mapping of cleidocranial dysplasia and evidence of a microdeletion in one family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Mutations and promoter SNPs in RUNX2, a transcriptional regulator of bone formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Association of functionally different RUNX2 P2 promoter alleles with BMD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Tumor suppressor activity of RUNX3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Transcriptional silencing of the RUNX3 gene by CpG hypermethylation is associated with lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Promoter structure of mouse RANKL/TRANCE/OPGL/ODF gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

Cell-specific patterns of Cbfa1 mRNA and protein expression in postnatal murine dental tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0722.2006.00399.X

10.1111/J.1600-0722.2006.00399.X

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference