(Q36620445)

15 August 2017

1 reference

title

The genetic dissection of essential hypertension (English)

1 reference

15 August 2017

Allen W Cowley

1

1 reference

15 August 2017

10 October 2006

1 reference

15 August 2017

Nature Reviews Genetics

1 reference

15 August 2017

7

1 reference

15 August 2017

829-840

1 reference

15 August 2017

11

1 reference

https://scigraph.springernature.com/pub.10.1038/nrg1967

15 August 2017

0 references

cites work

Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000.

1 reference

Large-scale search for genes predisposing to essential hypertension

31 March 2020

1 reference

Genetics of hypertension: from experimental models to clinical applications

31 March 2020

1 reference

Long-term control of arterial blood pressure

31 March 2020

1 reference

The kidney, hypertension, and obesity

31 March 2020

1 reference

Circulation: overall regulation

31 March 2020

1 reference

Blood pressure control--special role of the kidneys and body fluids

31 March 2020

1 reference

Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance?

31 March 2020

1 reference

Salt sensitivity in hypertension. Renal and cardiovascular implications

31 March 2020

1 reference

Hypertension and renal dysfunction: NHANES III.

31 March 2020

1 reference

Predictors of target organ damage in hypertensive blacks and whites

31 March 2020

1 reference

31 March 2020

Hypertension in blacks

1 reference

An international comparative study of blood pressure in populations of European vs. African descent

31 March 2020

1 reference

Transfer of a salt-resistant renin allele raises blood pressure in Dahl salt-sensitive rats

31 March 2020

1 reference

Salt susceptibility maps to chromosomes 1 and 17 with sex specificity in the Sabra rat model of hypertension

31 March 2020

1 reference

Genetically defined risk of salt sensitivity in an intercross of Brown Norway and Dahl S rats

31 March 2020

1 reference

Transfer of the Rf-1 region from FHH onto the ACI background increases susceptibility to renal impairment

31 March 2020

1 reference

A major gene locus links early onset albuminuria with renal interstitial fibrosis in the MWF rat with polygenetic albuminuria.

31 March 2020

1 reference

Impact of diet on blood pressure and age-related changes in blood pressure in the US population: analysis of NHANES III.

31 March 2020

1 reference

Salt sensitivity and resistance of blood pressure. Age and race as factors in physiological responses

31 March 2020

1 reference

Molecular genetics of human blood pressure variation

31 March 2020

1 reference

Multilocus linkage of familial hyperkalaemia and hypertension, pseudohypoaldosteronism type II, to chromosomes 1q31-42 and 17p11-q21

31 March 2020

1 reference

Molecular mechanisms of human hypertension

31 March 2020

1 reference

Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch

31 March 2020

1 reference

Human hypertension caused by mutations in WNK kinases

31 March 2020

1 reference

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

31 March 2020

1 reference

A cluster of metabolic defects caused by mutation in a mitochondrial tRNA.

31 March 2020

1 reference

A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension

31 March 2020

1 reference

Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase

31 March 2020

1 reference

Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase

31 March 2020

1 reference

Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy

31 March 2020

1 reference

Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel

31 March 2020

1 reference

A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity

31 March 2020

1 reference

A new locus on chromosome 12p13.3 for pseudohypoaldosteronism type II, an autosomal dominant form of hypertension

31 March 2020

1 reference

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

31 March 2020

1 reference

Present status of genetic mechanisms in hypertension

31 March 2020

1 reference

Molecular genetics of human hypertension

31 March 2020

1 reference

Linkage mapping for hypertension susceptibility genes

31 March 2020

1 reference

Genetics of human hypertension

31 March 2020

1 reference

Human chromosome 17 in essential hypertension

31 March 2020

1 reference

beta-Adducin polymorphisms, blood pressure, and sodium excretion in three European populations

31 March 2020

1 reference

Genetic dissection of complex traits

31 March 2020

1 reference

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

31 March 2020

1 reference

Mapping the new frontier: complex genetic disorders

31 March 2020

1 reference

A haplotype map of the human genome

31 March 2020

1 reference

Power tools for human genetics.

31 March 2020

1 reference

The International HapMap Project Web site

31 March 2020

1 reference

Sodium excretion as a modulator of genetic associations with cardiovascular phenotypes in the European Project on Genes in Hypertension

31 March 2020

1 reference

Dietary protein source determines the degree of hypertension and renal disease in the Dahl salt-sensitive rat.

31 March 2020

1 reference

Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree

31 March 2020

1 reference

Molecular basis of human hypertension: role of angiotensinogen

31 March 2020

1 reference

Angiotensinogen as a risk factor for essential hypertension in Japan

31 March 2020

1 reference

An association study of angiotensinogen polymorphisms with serum level and hypertension in an African-American population

31 March 2020

1 reference

Quantitative founder-effect analysis of French Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension

31 March 2020

1 reference

Identification of hypertension-related QTLs in African American sib pairs

31 March 2020

1 reference

Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study

31 March 2020

1 reference

An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians

31 March 2020

1 reference

Identification of genes for a complex trait: examples from hypertension

31 March 2020

1 reference

Genome-wide association studies for common diseases and complex traits

31 March 2020

1 reference

Statistical false positive or true disease pathway?

31 March 2020

1 reference

Whole-genome patterns of common DNA variation in three human populations

31 March 2020

1 reference

The gene encoding phosphodiesterase 4D confers risk of ischemic stroke.

31 March 2020

1 reference

Evaluation of single nucleotide polymorphisms in the phosphodiesterase 4D gene (PDE4D) and their association with ischaemic stroke in a large German cohort

31 March 2020

1 reference

Accurate multiplex polony sequencing of an evolved bacterial genome

31 March 2020

1 reference

New target regions for human hypertension via comparative genomics

31 March 2020

1 reference

Role of Genetic Factors in Susceptibility to Experimental Hypertension due to Chronic Excess Salt Ingestion

31 March 2020

1 reference

Dahl salt-susceptible and salt-resistant rats. A review

31 March 2020

1 reference

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat

31 March 2020

1 reference

Isolation of microdissection clones from rat chromosome 10.

31 March 2020

1 reference

Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat

31 March 2020

1 reference

Strain-specific deletions in exon 10 of rat K-kininogen and T1-kininogen genes allow mapping of both genes to rat chromosome 11.

31 March 2020

1 reference

Independent genetic susceptibility to cardiac hypertrophy in inherited hypertension

31 March 2020

1 reference

Genome sequence of the Brown Norway rat yields insights into mammalian evolution

31 March 2020

1 reference

Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat

31 March 2020

1 reference

Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat.

31 March 2020

1 reference

A genomic-systems biology map for cardiovascular function

31 March 2020

1 reference

Congenic strains confirm the presence of salt-sensitivity QTLs on chromosome 1 in the Sabra rat model of hypertension

31 March 2020

1 reference

Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats

31 March 2020

1 reference

Finding genes that underlie complex traits

31 March 2020

1 reference

Effect of genetic background on cosegregation of renin alleles and blood pressure in Dahl rats.

31 March 2020

1 reference

Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats

31 March 2020

1 reference

Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos

31 March 2020

1 reference

Analysing complex genetic traits with chromosome substitution strains

31 March 2020

1 reference

Genetic dissection of complex traits with chromosome substitution strains of mice.

31 March 2020

1 reference

Consomic rat model systems for physiological genomics

31 March 2020

1 reference

Application of chromosomal substitution techniques in gene-function discovery

31 March 2020

1 reference

Use of a panel of congenic strains to evaluate differentially expressed genes as candidate genes for blood pressure quantitative trait loci

31 March 2020

1 reference

Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension

31 March 2020

1 reference

The use of designer rats in the genetic dissection of hypertension

31 March 2020

1 reference

Novel integrative approaches to the identification of candidate genes in hypertension

31 March 2020

1 reference

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.

31 March 2020

1 reference

Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression.

31 March 2020

1 reference

High throughput gene expression profiling: a molecular approach to integrative physiology

31 March 2020

1 reference

Significance analysis of time course microarray experiments

31 March 2020

1 reference

Sex-specific effects of dual ET-1/ANG II receptor (Dear) variants in Dahl salt-sensitive/resistant hypertension rat model

31 March 2020

1 reference

The sex-specific genetic architecture of quantitative traits in humans

31 March 2020

1 reference

Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population

31 March 2020

1 reference

X-inactivation profile reveals extensive variability in X-linked gene expression in females

31 March 2020

1 reference

Association of Estrogen Receptor β Gene Polymorphisms With Left Ventricular Mass and Wall Thickness in Women

31 March 2020

1 reference

Sexual dimorphism in mammalian gene expression

31 March 2020

1 reference

Monosodium glutamate neurotoxicity: a sex-specific impairment of blood pressure but not vasopressin in developing rats.

31 March 2020

1 reference

Sex-specific differences in cerebral arterial myogenic tone in hypertensive and normotensive rats.

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1967

1 reference

15 August 2017

1 reference

PubMed ID

17033627