(Q36627204)

15 August 2017

1 reference

title

Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed? (English)

1 reference

15 August 2017

1 reference

1

Svein I Johannessen

1 reference

15 August 2017

Torbjörn Tomson

2

1 reference

15 August 2017

publication date

1 January 2006

1 reference

Clinical Pharmacokinetics

15 August 2017

published in

1 reference

15 August 2017

volume

45

1 reference

15 August 2017

issue

11

1 reference

15 August 2017

page(s)

1061-1075

1 reference

Felbamate for partial seizures: results of a controlled clinical trial

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Lamotrigine clearance during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Gestation-induced changes in lamotrigine pharmacokinetics: a monotherapy study

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

The impact of pregnancy and childbirth on the metabolism of lamotrigine.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Oral contraceptives reduce lamotrigine plasma levels

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Sodium valproate acutely inhibits lamotrigine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Lamotrigine toxicity secondary to sertraline

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

The pharmacokinetics of oxcarbazepine and its active metabolite 10-hydroxy-carbazepine in healthy subjects and in epileptic patients treated with phenobarbitone or valproic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

A double-blind, placebo-controlled interaction study between oxcarbazepine and carbamazepine, sodium valproate and phenytoin in epileptic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

A single-dose study to define tiagabine pharmacokinetics in pediatric patients with complex partial seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Randomized, concentration-controlled trial of topiramate in refractory focal epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Clinical pharmacology of vigabatrin

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Vigabatrin-induced decrease in serum phenytoin concentration does not involve a change in phenytoin bioavailability.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200645110-00002

Single-dose pharmacokinetics of felbamate in patients with renal dysfunction

21 January 2018

1 reference

12 December 2020

Population pharmacokinetics of lamotrigine monotherapy in patients with epilepsy: retrospective analysis of routine monitoring data

1 reference

12 December 2020

Comparative anticonvulsant and mechanistic profile of the established and newer antiepileptic drugs

1 reference

12 December 2020

Pharmacokinetics of lamotrigine in patients with renal impairment: influence of haemodialysis

1 reference

12 December 2020

Changes in the disposition of oxcarbazepine and its metabolites during pregnancy and the puerperium

1 reference

12 December 2020

Comparison of the steady-state pharmacokinetics of topiramate and valproate in patients with epilepsy during monotherapy and concomitant therapy

1 reference

12 December 2020

Is there a role for therapeutic drug monitoring of new anticonvulsants?

1 reference

12 December 2020

Vigabatrin serum concentration to dosage ratio: influence of age and associated antiepileptic drugs.

1 reference

12 December 2020

The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes

1 reference

12 December 2020

Gender aspects of pharmacokinetics of new and old AEDs: pregnancy and breast-feeding

1 reference

12 December 2020

The pharmacokinetic and pharmacodynamic consequences of the co-administration of lamotrigine and a combined oral contraceptive in healthy female subjects

1 reference

12 December 2020

Bidirectional interaction of valproate and lamotrigine in healthy subjects.

1 reference

12 December 2020

Oxcarbazepine pharmacokinetics and tolerability in children with inadequately controlled epilepsy

1 reference

12 December 2020

Efficacy, tolerability, and kinetics of lamotrigine in infants

1 reference

12 December 2020

How high can we go with phenytoin?

1 reference

12 December 2020

The influence of dosage, age, and comedication on steady state plasma lamotrigine concentrations in epileptic children: a prospective study with preliminary assessment of correlations with clinical response

1 reference

12 December 2020

Levetiracetam therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs

1 reference

12 December 2020

Topiramate serum concentration-to-dose ratio: influence of age and concomitant antiepileptic drugs and monitoring implications

1 reference

12 December 2020

Clinical pharmacology and pharmacokinetics of oxcarbazepine

1 reference

12 December 2020

The effect of renal impairment on the pharmacokinetics of oxcarbazepine and its metabolites

1 reference

12 December 2020

Lamotrigine in pregnancy: pharmacokinetics during delivery, in the neonate, and during lactation

1 reference

12 December 2020

Population pharmacokinetics of gabapentin in infants and children

1 reference

12 December 2020

Single and multiple dose pharmacokinetics of felbamate in the elderly

1 reference

12 December 2020

Topiramate in refractory epilepsy: a prospective observational study

1 reference

12 December 2020

Serum concentrations of Levetiracetam in epileptic patients: the influence of dose and co-medication

1 reference

12 December 2020

Pharmacokinetics of tiagabine as add-on therapy in patients taking enzyme-inducing antiepilepsy drugs

1 reference

12 December 2020

Potentially reactive cyclic carbamate metabolite of the antiepileptic drug felbamate produced by human liver tissue in vitro

1 reference

12 December 2020

Oxcarbazepine: pharmacokinetic interactions and their clinical relevance

1 reference

12 December 2020

Analysis of pregabalin at therapeutic concentrations in human plasma/serum by reversed-phase HPLC.

1 reference

12 December 2020

Topiramate pharmacokinetics in children and adults with epilepsy: a case-matched comparison based on therapeutic drug monitoring data

1 reference

12 December 2020

Synthesis and in vitro reactivity of 3-carbamoyl-2-phenylpropionaldehyde and 2-phenylpropenal: putative reactive metabolites of felbamate.

1 reference

12 December 2020

Long-term follow-up using a higher target range for lamotrigine monitoring

1 reference

12 December 2020

Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action

1 reference

12 December 2020

The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy

1 reference

12 December 2020

Zonisamide enhances slow sodium inactivation in Myxicola

1 reference

12 December 2020

Clinical experience with topiramate dosing and serum levels in patients with epilepsy.

1 reference

12 December 2020

Interlaboratory variability in the quantification of new generation antiepileptic drugs based on external quality assessment data

1 reference

12 December 2020

Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?

1 reference

12 December 2020

Simultaneous stereoselective high-performance liquid chromatographic determination of 10-hydroxycarbazepine and its metabolite carbamazepine-10,11-trans-dihydrodiol in human urine

1 reference

12 December 2020

Identification of modified atropaldehyde mercapturic acids in rat and human urine after felbamate administration

1 reference

12 December 2020

The anticonvulsant zonisamide scavenges free radicals

1 reference

12 December 2020

Action of GP 47779, the active metabolite of oxcarbazepine, on the corticostriatal system. I. Modulation of corticostriatal synaptic transmission

1 reference

12 December 2020

Effects of rifampicin and cimetidine on pharmacokinetics and pharmacodynamics of lamotrigine in healthy subjects

1 reference

12 December 2020

Survey of 260 epileptic patients treated with oxcarbazepine (Trileptal) on a named-patient basis

1 reference

12 December 2020

Pharmacokinetics of lamotrigine in children in the absence of other antiepileptic drugs

1 reference

12 December 2020

A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of the lack of proportionality between increasing dose and drug levels in plasma

1 reference

12 December 2020

Anticonvulsant action of oxcarbazepine, hydroxycarbamazepine, and carbamazepine against metrazol-induced motor seizures in developing rats

1 reference

12 December 2020

Cellular and molecular actions of lamotrigine: Possible mechanisms of efficacy in bipolar disorder

1 reference

12 December 2020

Felbamate. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in epilepsy

1 reference

12 December 2020

Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy

1 reference

12 December 2020

Therapeutic experiences with 947 epileptic out-patients in oxcarbazepine treatment

1 reference

12 December 2020

Can pharmacokinetic variability be controlled for the patient's benefit? The place of TDM for new AEDs

1 reference

12 December 2020

Age and antiepileptic drugs influence topiramate plasma levels in children.

1 reference

12 December 2020

10-Hydroxycarbazepine serum concentration-to-oxcarbazepine dose ratio: influence of age and concomitant antiepileptic drugs

1 reference

12 December 2020

Effects of dextropropoxyphene on the steady-state kinetics of oxcarbazepine and its metabolites

1 reference

12 December 2020

The influence of age on the pharmacokinetics of the antiepileptic agent oxcarbazepine

1 reference

12 December 2020

Pharmacokinetics of levetiracetam

1 reference

12 December 2020

Pregabalin pharmacology and its relevance to clinical practice

1 reference

12 December 2020

Lamotrigine. An update of its pharmacology and therapeutic use in epilepsy

1 reference

12 December 2020

Discontinuation of phenytoin and carbamazepine in patients receiving felbamate

1 reference

12 December 2020

Therapeutic drug monitoring of the newer antiepileptic drugs

1 reference

12 December 2020

Topiramate. A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of epilepsy

1 reference

12 December 2020

Oxcarbazepine: an update of its efficacy in the management of epilepsy

1 reference

12 December 2020

Zonisamide monotherapy with once-daily dosing in children with cryptogenic localization-related epilepsies: clinical effects and pharmacokinetic studies

1 reference

12 December 2020

Tiagabine in the treatment of epilepsy--a clinical review with a guide for the prescribing physician

1 reference

12 December 2020

Pharmacokinetics and metabolism of gabapentin in rat, dog and man.

1 reference

12 December 2020

Single-dose pharmacokinetics of lamotrigine in children: influence of age and antiepileptic comedication.

1 reference

12 December 2020

Nuclear magnetic resonance detection of increased cortical GABA in vigabatrin-treated rats in vivo.

1 reference

12 December 2020

Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy

1 reference

12 December 2020

Pharmacokinetic interactions of topiramate

1 reference

12 December 2020

Pharmacokinetics and safety of tiagabine in subjects with various degrees of hepatic function

1 reference

12 December 2020

Serum concentrations and effects of gabapentin and vigabatrin: observations from a dose titration study

1 reference

12 December 2020

Pharmacokinetic profile of levetiracetam: toward ideal characteristics

1 reference

12 December 2020

The clinical pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine

1 reference

12 December 2020

Ethinyl estradiol, not progestogens, reduces lamotrigine serum concentrations.

1 reference

12 December 2020

Pharmacokinetic drug interactions in children taking oxcarbazepine

1 reference

12 December 2020

Pharmacokinetics of W-554 (ADD 03055) in epileptic patients.

1 reference

12 December 2020

Plasma gabapentin concentrations in children with epilepsy: influence of age, relationship with dosage, and preliminary observations on correlation with clinical response

1 reference

12 December 2020

Influence of oxcarbazepine and methsuximide on lamotrigine concentrations in epileptic patients with and without valproic acid comedication: results of a retrospective study

1 reference

12 December 2020

The new generation of GABA enhancers. Potential in the treatment of epilepsy

1 reference

12 December 2020

Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex

1 reference

12 December 2020

The effect of age on the apparent clearance of felbamate: a retrospective analysis using nonlinear mixed-effects modeling

1 reference

12 December 2020

Felbamate levels in patients with epilepsy

1 reference

12 December 2020

Enantioselective pharmacokinetics of 10-hydroxycarbazepine after oral administration of oxcarbazepine to healthy Chinese subjects

1 reference

12 December 2020

Lack of clinically significant pharmacokinetic interactions between zonisamide and lamotrigine at steady state in patients with epilepsy

1 reference

12 December 2020

Clinical pharmacology and therapeutic drug monitoring of zonisamide.

1 reference

12 December 2020

If a well-stabilized epileptic patient has a subtherapeutic antiepileptic drug level, should the dose be increased? A randomized prospective study

1 reference

12 December 2020

Association between patient age and gabapentin serum concentration-to-dose ratio: a preliminary multivariate analysis

1 reference

12 December 2020

Influence of dosage, age, and co-medication on plasma topiramate concentrations in children and adults with severe epilepsy and preliminary observations on correlations with clinical response

1 reference

12 December 2020

Use of levetiracetam in special populations

1 reference

12 December 2020

Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII)

1 reference

12 December 2020

Lamotrigine serum concentration-to-dose ratio: influence of age and concomitant antiepileptic drugs and dosage implications

1 reference

12 December 2020

Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part II. Phenytoin, carbamazepine, sulthiame, lamotrigine, vigabatrin, oxcarbazepine and felbamate

1 reference

12 December 2020

Absence of interaction between oxcarbazepine and erythromycin

1 reference

12 December 2020

Pharmacokinetic Interactions Between Lamotrigine and Other Antiepileptic Drugs in Children with Intractable Epilepsy

1 reference

12 December 2020

Tiagabine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of epilepsy

1 reference

12 December 2020

Pregabalin: as adjunctive treatment of partial seizures

1 reference

12 December 2020

10.2165/00003088-200645110-00002

Identifiers

DOI

1 reference

Dimensions Publication ID

15 August 2017

1006604454

0 references

1 reference